Abstract Number: 1069 • 2017 ACR/ARHP Annual Meeting
Significantly Elevated Serum Protein-Adduction with 4-Hydroxy-2-Nonenal but Not Malondialdehyde in Sjogren’s Syndrome
Background/Purpose: Sjögren’s syndrome (SS) is a chronic inflammatory, autoimmune disorder characterized by diminished lacrimal and salivary gland secretion resulting in keratoconjunctivitis sicca and xerostomia. Autoantibodies,…Abstract Number: 1795 • 2017 ACR/ARHP Annual Meeting
IL-7 in Primary Sjogren Syndrome (pSS) Is Secreted By Salivary Gland Epithelial Cells after IFN Stimulation and Is Associated with B-Cell Activation
Background/Purpose : pSS is characterized by a strong IFN signature, ectopic germinal centers formation and a chronic blood lymphopenia. IL-7 plays a central part in…Abstract Number: 565 • 2017 ACR/ARHP Annual Meeting
Fatigue in Primary Sjögren’s Syndrome (pSS) Is Associated with Lower Levels of Proinflammatory Cytokines: A Validation Study
Background/Purpose: Primary Sjögren’s syndrome (pSS) is a chronic autoimmune rheumatic disease causing various symptoms including dryness, fatigue and pain. Previous work by our group has…Abstract Number: 1479 • 2017 ACR/ARHP Annual Meeting
Difference in Clinical Presentation between Female and Male Patients with Primary Sjogren’s Syndrome at Diagnosis and in Long-Term Follow-up
Background/Purpose: Despite men being less prone to develop autoimmune diseases, male sex has been associated with a more severe disease course in several systemic autoimmune…Abstract Number: 2022 • 2017 ACR/ARHP Annual Meeting
Diagnostic and Prognostic VALUE of Salivary GLAND Ultrasonography in Primary Sjögren’s Syndrome: a Preliminary Study
Background/Purpose: In recent years, salivary gland ultrasonography (SGUS) has emerged as a promising tool for the diagnosis and prognostic stratification of patiens with primary Sjögren’s…Abstract Number: 566 • 2017 ACR/ARHP Annual Meeting
Immune Response to Seasonal Flu Vaccination in Patients with Primary Sjogren’s Syndrome
Background/Purpose: Vaccination of rheumatic patients has been reported to induce lower antibody titers than in healthy individuals. However, studies have primarily included patients treated with…Abstract Number: 1480 • 2017 ACR/ARHP Annual Meeting
Risk of Ischemic Stroke in Sjögren’s Syndrome Patients: A Systematic Review and Meta-Analysis
Background/Purpose: Primary Sjögren’s syndrome (SS) is an autoimmune disease of the exocrine glands with lymphocytic infiltration into lacrimal and salivary glands. Autoimmune diseases increase cardiovascular…Abstract Number: 2123 • 2017 ACR/ARHP Annual Meeting
Protein-Losing Enteropathy in Patients with Systemic Autoimmune Diseases: Characterization of 263 Cases (GEAS-SEMI Spanish Cohort)
Background/Purpose: Protein-losing enteropathy (PLE) is a rare condition characterized by a loss of serum protein into the gastrointestinal tract resulting in hypoproteinemia, which can be…Abstract Number: 569 • 2017 ACR/ARHP Annual Meeting
Is the Oral Microbiome Involved in the Pathogenesis of Sjogren’s Syndrome?
Background/Purpose: Environmental factors involved in the pathogenesis of primary Sjögren’s syndrome (pSS) are still largely unknown. The oral cavity is the microbial habitat closest to…Abstract Number: 1481 • 2017 ACR/ARHP Annual Meeting
Risk of Ischemic Heart Disease in Sjögren’s Syndrome Patients: A Systematic Review and Meta-Analysis of Observational Studies
Background/Purpose: Systemic lupus erythematosus (SLE) and rheumatoid arthritis (RA) are associated with an increased risk of ischemic heart disease (IHD). The risk of IHD in…Abstract Number: 2703 • 2017 ACR/ARHP Annual Meeting
Single Cell Analysis of TCRs from CD8+ T Cells in Sjogren’s Syndrome
Background/Purpose: Sjögren’s syndrome (SS) is an autoimmune exocrinopathy characterized by focal lymphocytic infiltration of the salivary and lacrimal glands, severe dry eyes and mouth, fatigue…Abstract Number: 570 • 2017 ACR/ARHP Annual Meeting
Signalling Pathways Identified in Salivary Glands from Primary Sjögren’s Syndrome Patients Reveal Enhanced Adipose Tissue Development, As Demonstrated By Microarray Analysis, Real-Time PCR and Immunohistochemistry
Background/Purpose: : A characteristic feature of Sjögren’s syndrome (SS) is the destruction of salivary and lacrimal glands mediated by mononuclear cell infiltration. Adipocytes can also…Abstract Number: 1482 • 2017 ACR/ARHP Annual Meeting
Preliminary Population-Based Incidence and Prevalence Estimates of Primary Sjogren’s Syndrome from the Manhattan Lupus Surveillance Program
Background/Purpose: The extant epidemiologic data of Primary Sjögren’s Syndrome (pSS) remains limited with few published estimates for the general population and little data regarding racial/ethnic…Abstract Number: 2706 • 2017 ACR/ARHP Annual Meeting
T Follicular-Helper CELLS (TFH) Enrichment and T Follicular-Regulatory CELLS (TFR) Exclusion from Ectopic Germinal Centers in Salivary Glands of Sjogren’s Syndrome Patients
Background/Purpose: Lymphocytic aggregates in the salivary glands (SG) of Sjögren’s syndrome (SS) can organize in ectopic lymphoid structures (ELS) forming functional germinal centers (GCs), which…Abstract Number: 572 • 2017 ACR/ARHP Annual Meeting
Biopsy Accuracy in Sjögren’s Syndrome: Analysis of 803 Patients Presenting with Sicca Syndrome Referred to Labial Salivary Gland Biopsy
Background/Purpose: Labial salivary gland biopsy (LSGB) is a minimally invasive procedure used in the diagnostic of Sjögren's Syndrome (SS). Objectives: to describe demographic, clinical and…
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