Abstract Number: 2954 • 2015 ACR/ARHP Annual Meeting
Serum and CSF Biomarkers of Neuropsychiatric Involvement in Primary Sjogren Syndrome and Systemic Lupus Erythematosus
Background/Purpose: Neuropsychiatric manifestations are commonly observed in both SLE and primary Sjšgren's syndrome (pSS). However, making an accurate diagnosis can be challenging. Multiple serum and…Abstract Number: 625 • 2015 ACR/ARHP Annual Meeting
Sjögren’s Syndrome Foundation Clinical Practice Guidelines for Management of Systemic Disease
Background/Purpose: There are currently no FDA approved immunomodulating agents available for treatment of the extraglandular manifestations of Sjogren’s (SS). Clinical practice guidelines were developed for…Abstract Number: 647 • 2015 ACR/ARHP Annual Meeting
Involvement of Peripheral Nervous System in Primary Sjögren Syndrome, a Gessar Analysis
Background/Purpose: Primary Sjögren's syndrome (pSS) is an autoimmune disease characterized by dysfunction of the exocrine glands. The frequency of neurological manifestations in pSS ranges from…Abstract Number: 2282 • 2015 ACR/ARHP Annual Meeting
“Doing Every-Day Life” with Primary Sjögren’s Syndrome: Factors Predicting Difficulties Performing Daily Activities and Taking on Life Roles
Background/Purpose: Primary Sjögren’s Syndrome (pSS) is an autoimmune disease which targets secretory glands and results in dryness. In addition pSS patients frequently experience symptoms of…Abstract Number: 3200 • 2015 ACR/ARHP Annual Meeting
Characterization of Early and Progressive Autoimmunity in Sjogrens Syndrome: The Incomplete Sjogrens Syndrome Model
Background/Purpose: Autoimmune diseases are often preceded by subclinical serologic and functional abnormalities that predate diagnosis by several years. The insidious and progressive nature of these…Abstract Number: 626 • 2015 ACR/ARHP Annual Meeting
Efficacy of Belimumab and Targeting of Rheumatoid Factor Positive B-Cells in Sjögren’s Syndrome: Follow-up of the Open-Label Phase II Study
Background/Purpose: Belimumab, a monoclonal anti-B lymphocyte Stimulator (BLyS) antibody is preliminary found to be effective in Sjögren’s syndrome (SS) patients with moderate to high systemic…Abstract Number: 648 • 2015 ACR/ARHP Annual Meeting
Klinefelter’s Syndrome (47,XXY) Among Men with Sjögren’s Syndrome
Background/Purpose: Primary Sjögren’s syndrome (pSS) has a strong female bias of greater than 10 to 1. This difference in risk of disease between the sexes…Abstract Number: 2516 • 2015 ACR/ARHP Annual Meeting
Association Between Primary Sjögren’s Syndrome and Pregnancy Outcome: A Systematic Review and Meta-Analysis
Background/Purpose: Systemic autoimmune disorders may interfere with normal reproductive function resulting in negative outcome of pregnancy. Primary Sjögren's syndrome (pSS) is a common rheumatic disease…Abstract Number: 3201 • 2015 ACR/ARHP Annual Meeting
IL-7 Drives Cytokine Secretion of IL-7Rabright CCR9-Expressing T-Follicular Helper-like Cells: Potential New Axis in Lymphoid Neogenesis in Salivary Glands of Primary Sjogren s Syndrome Patients
Background/Purpose: In primary Sjögren’s syndrome (pSS) B cell hyperactivity including autoantibody secretion and lymphoma development are hallmark immunopathological features. Specific lymphoid organization (including germinal centers)…Abstract Number: 627 • 2015 ACR/ARHP Annual Meeting
Clinical Subsets and Presenting Features in Primary Sjögren’s Syndrome: Results from a Single Center Inception Cohort Study
Background/Purpose: Aim of the study was to characterize the spectrum of presenting clinical features in a single-centre inception cohort of patients with primary Sjögren’s syndrome…Abstract Number: 1051 • 2015 ACR/ARHP Annual Meeting
Serum Calprotectin As Biomarker of Carotid Atherosclerosis in Patients with Primary Sjögren’s Syndrome
Background/Purpose: The relationship between atherosclerosis, traditional risk factors, disease activity and biomarkers is not well explored. We aimed to identify the association of carotid atherosclerosis…Abstract Number: 2517 • 2015 ACR/ARHP Annual Meeting
Primary Sjögren’s Syndrome and Pregnancy: Evolution of Thyroid Function, Xerostomia, Xerophthalmia and Salivary Test for Dental Caries Risk
Background/Purpose: 1. To study the effect of pregnancy in PSS patients on oral and ocular dryness and the salivary test for dental caries activity. 2.…Abstract Number: 3202 • 2015 ACR/ARHP Annual Meeting
Functional Anti-Muscarinic Receptor-3 Monoclonal Antibodies Derived from Salivary Gland in Patients of Sjögren’s Syndrome
Background/Purpose: Sjögren's syndrome (SS) is a chronic autoimmune inflammatory disease characterized by bilateral hypofunction of lacrimal and salivary glands leading to keratoconjuctivitis and xerostomia. The…Abstract Number: 628 • 2015 ACR/ARHP Annual Meeting
Poor Prognosis of Patients with Primary Sjögren Syndrome Who Fulfilled at Diagnosis the Classification Criteria for Concomitant Cryoglobulinemic Vasculitis
Background/Purpose: To evaluate the fulfilment of classification criteria for cryoglobulinemic vasculitis (CV) at diagnosis in a large cohort of patients with primary Sjögren syndrome (SS)…Abstract Number: 1052 • 2015 ACR/ARHP Annual Meeting
Identification of Novel Sjogren’s Syndrome Risk Loci in the Regions of TNFAIP3 and PRDM1
Background/Purpose: Sjögren’s syndrome (SS) is a complex autoimmune disease with both environmental and genetic factors playing important roles in its pathophysiology. The goal of this…
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