Abstract Number: 1496 • 2017 ACR/ARHP Annual Meeting
The Performance of Different Classification Criteria in Patients with Primary Sjogren’s Syndrome and Analysis of Their Contribution for Definitive Diagnosis, When Either Criteria Used Alone or in Combination
Background/Purpose: Many classification criteria sets have for primary Sjšgren's Syndrome (pSS).We aimed to compare the performance of 3 classification criteria sets for pSS, to determine…Abstract Number: 2877 • 2017 ACR/ARHP Annual Meeting
Premature Senescence of Naive CD4+ T-Cells in Primary Sjogren’s Syndrome
Background/Purpose: Lymphopenia is a frequent finding in primary Sjögren’s syndrome (pSS) affecting mostly the CD4+ T-cell population. Here we examine possible underlying defects in thymic…Abstract Number: 556 • 2017 ACR/ARHP Annual Meeting
Identification and Validation of S100 Salivary Proteins As Putative Biomarkers for Different Subsets of Primary Sjögren’s Syndrome Patients
Background/Purpose: S100 A proteins are multifunctional proteins expressed predominantly by myeloid cells, with a regulatory role in a variety of cellular processes including inflammation. Recently,…Abstract Number: 877 • 2017 ACR/ARHP Annual Meeting
Modification of the Classification Criteria for Primary Sjögren Syndrome: An International Vignette Survey
Background/Purpose: The common classification criteria sets of primary Sjogren syndrome, did not considered the ultrasonography (US) of the major salivary glands as a useful item.…Abstract Number: 1498 • 2017 ACR/ARHP Annual Meeting
Long-Term Cohort of Patients with a Clinical Diagnosis of Sjogren’s Syndrome: Activity Index and Patient Reported Outcome Performance
Background/Purpose: There have been three classification proposals for Sjögren´s Syndrome (SS) over the past 15 years (1-3). The 2016 criteria require a diagnostic work-up which…Abstract Number: 557 • 2017 ACR/ARHP Annual Meeting
Enhanced Expression of NLRP3 Inflammasome-Related Inflammation in Peripheral Blood Mononuclear Cells in Sjögren’s Syndrome
Background/Purpose: Sjögren's syndrome is a systemic autoimmune disease characterized by lymphocyte infiltration and subsequent dysfunction of exocrine glands, finally leading to dryness in the exocrine…Abstract Number: 878 • 2017 ACR/ARHP Annual Meeting
Diagnosis of Salivary Gland Lymphoma in Sjogren’s Syndrome Utilizing Ultrasound-Guided Core Needle Biopsies
Background/Purpose: Ultrasound (US)-guided core needle biopsy (CNB) with or without concomitant fine needle aspiration (FNA) is a standard method for pre-operative evaluation of salivary gland…Abstract Number: 1499 • 2017 ACR/ARHP Annual Meeting
Major Salivary Gland Ultrasonography Bed-Side and Still Image Scoring – a Pilot Comparison in Juvenile Sjögren’s Syndrome
Background/Purpose: Adding major salivary gland ultrasonography (SGUS) improves the diagnostics of primary Sjögren’s syndrome (pSS). Juvenile Sjögren’s syndrome (jSS) is a rare, poorly defined disease.…Abstract Number: 560 • 2017 ACR/ARHP Annual Meeting
Clinical Relevance of Serum Free Light Chain Level As Biomarker in Primary Sjögren′s Syndrome
Background/Purpose: During immunoglobulin synthesis in B-cells, kappa and lambda light chains are produced in excess compared to heavy chains, and the surplus of light chains…Abstract Number: 1064 • 2017 ACR/ARHP Annual Meeting
Characterization of Human Tolerogenic Dendritic Cells Generated with Protein Kinase C Inhibitor and Induction from Patients with Autoimmune Diseases
Background/Purpose: Tolerogenic dendritic cells (tDCs) are a promising therapeutic tool for specific induction of immunological tolerance. Human tDCs can be generated ex vivo using various…Abstract Number: 1500 • 2017 ACR/ARHP Annual Meeting
Longitudinal Analysis of Different Therapeutic Strategies in Patients with Primary Sjögren’s Syndrome
Background/Purpose: Primary Sjögren’s syndrome (pSS) is a systemic autoimmune rheumatic disease characterised by sicca features and systemic manifestations such as pain and fatigue. The classic…Abstract Number: 562 • 2017 ACR/ARHP Annual Meeting
Anti-Muscarinic Receptor 3 Antibodies – a Cross Reactive Result of Ro60 Immunization
Background/Purpose: Sjogren’s syndrome (SS) is a chronic autoimmune inflammatory disease characterized by impaired function of salivary and lacrimal glands leading to dry mouth and dry…Abstract Number: 1069 • 2017 ACR/ARHP Annual Meeting
Significantly Elevated Serum Protein-Adduction with 4-Hydroxy-2-Nonenal but Not Malondialdehyde in Sjogren’s Syndrome
Background/Purpose: Sjögren’s syndrome (SS) is a chronic inflammatory, autoimmune disorder characterized by diminished lacrimal and salivary gland secretion resulting in keratoconjunctivitis sicca and xerostomia. Autoantibodies,…Abstract Number: 1795 • 2017 ACR/ARHP Annual Meeting
IL-7 in Primary Sjogren Syndrome (pSS) Is Secreted By Salivary Gland Epithelial Cells after IFN Stimulation and Is Associated with B-Cell Activation
Background/Purpose : pSS is characterized by a strong IFN signature, ectopic germinal centers formation and a chronic blood lymphopenia. IL-7 plays a central part in…Abstract Number: 565 • 2017 ACR/ARHP Annual Meeting
Fatigue in Primary Sjögren’s Syndrome (pSS) Is Associated with Lower Levels of Proinflammatory Cytokines: A Validation Study
Background/Purpose: Primary Sjögren’s syndrome (pSS) is a chronic autoimmune rheumatic disease causing various symptoms including dryness, fatigue and pain. Previous work by our group has…
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