Abstracts tagged "Sjogren’s syndrome and T cells"

Abstract Number: 2885 • 2018 ACR/ARHP Annual Meeting
Expansion of Activated PD-1+ ICOS+ T Follicular and Peripheral Helper Cells in Primary Sjögren’s Syndrome Associates with Abnormalities in B Cell Compartment
Nida Meednu¹, Jennifer Albrecht², Madhu Ramaswamy³, Jeffrey Riggs⁴, Alex Rosenberg⁵, Jamie Biear⁶, Ralf G. Thiele⁷, Andreea Coca², Gianluca Carlesso³ and Jennifer Anolik², ¹Medicine- Allergy, Immunology and Rheumatology, University of Rochester Medical Center, Rochester, NY, ²University of Rochester Medical Center, Rochester, NY, ³MedImmune LLC, Gaithersburg, MD, ⁴Respiratory, Inflammation and Autoimmunity (RIA), MedImmune LLC, Gaithersburg, MD, ⁵University of Alabama at Birmingham, Birmingham, AL, ⁶Rheumatology, University of Rochester Medical Center, Rochester, NY, ⁷Division of Rheumatology, University of Rochester Medical Center, Rochester, NY
Background/Purpose: Primary Sjögren’s syndrome (pSS) is a systemic autoimmune disease characterized by immune cell infiltration in the salivary glands resulting in ocular and oral dryness.…
Abstract Number: 561 • 2017 ACR/ARHP Annual Meeting
Comprehensive Immuno-Phenotyping of Follicular Helper T Cell and B Cell Subpopulations in Primary Sjögren’s Syndrome
Nida Meednu¹, Cécile Seifert², Jennifer Barnard³, Madhu Ramaswamy⁴, Jeffrey Riggs⁵, Alex Rosenberg⁶, Jamie Biear⁷, Gianluca Carlesso⁴, Ralf G. Thiele⁸, Andreea Coca⁹, Fanny Monneaux², Helene Dumortier², Jacques-Eric Gottenberg² and Jennifer H. Anolik¹, ¹Medicine- Allergy, Immunology and Rheumatology, University of Rochester Medical Center, Rochester, NY, ²CNRS, Immunopathologie et Chimie Thérapeutique/Laboratory of Excellence Medalis, Institut de Biologie Moléculaire et Cellulaire, Strasbourg, France, ³Medicine-Allergy, Immunology and Rheumatology, University of Rochester Medical Center, Rochester, NY, ⁴MedImmune LLC, Gaithersburg, MD, ⁵Respiratory, Inflammation and Autoimmunity (RIA), MedImmune LLC, Gaithersburg, MD, ⁶Department of Microbiology and Informatics Institute, University of Alabama at Birmingham, Birmingham, AL, ⁷Rheumatology, University of Rochester Medical Center, Rochester, NY, ⁸Medicine, University of Rochester Medical Center, Rochester, NY, ⁹University of Rochester Medical Center, Rochester, NY
Background/Purpose: Primary Sjögren’s syndrome (pSS) is a systemic autoimmune disease characterized by immune cell infiltration in the salivary glands resulting in ocular and oral dryness.…
Abstract Number: 655 • 2016 ACR/ARHP Annual Meeting
Comprehensive Immuno-Phenotyping of Follicular Helper T Cells and B Cell Subpopulations in Primary Sjögren’s Syndrome
Nida Meednu¹, Cécile Seifert², Jennifer Barnard³, Madhu Ramaswamy⁴, Jeffrey Riggs⁴, Alex Rosenberg³, Jamie Biear⁵, Gianluca Carlesso⁴, Ralf G. Thiele⁶, Andreea Coca³, Fanny Monneaux², Helene Dumortier², Jacques-Eric Gottenberg^2,7 and Jennifer H. Anolik³, ¹Medicine- Allergy, Immunology and Rheumatology, University of Rochester Medical Center, Rochester, NY, ²CNRS, Immunopathologie et Chimie Thérapeutique/Laboratory of Excellence Medalis, Institut de Biologie Moléculaire et Cellulaire, Strasbourg, France, ³University of Rochester Medical Center, Rochester, NY, ⁴MedImmune LLC, Gaithersburg, MD, ⁵Rheumatology, University of Rochester Medical Center, Rochester, NY, ⁶Medicine, University of Rochester Medical Center, Rochester, NY, ⁷Department of Rheumatology, Strasbourg University Hospital, Strasbourg, France
Background/Purpose: Primary Sjögren’s syndrome (pSS) is a systemic autoimmune disease characterized by immune cell infiltration in the salivary glands resulting in ocular and oral dryness.…
Abstract Number: 511 • 2012 ACR/ARHP Annual Meeting
A New Pathogenic Role of Salivary Gland Epithelial Cells in the Costimulation of T Lymphocytes in Primary Sjögren’s Syndrome: 0X40 Ligand Expression, T-Cell Induction of OX40 and Promotion of T-Cell Survival, Proliferation and Activation
Yazhuo Gong, Ghada Alsaleh, Jean Sibilia and Jacques-Eric Gottenberg, Université de Strasbourg, EA4438 Laboratoire Physiopathologie des Arthrites, Illkirch-Strasbourg, France
Background/Purpose: OX40/OX40L interaction is a pivotal costimulatory pathway involved in multiple autoimmune diseases. It provides a key signal for T-cell proliferation and differentiation in effector…

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