Abstracts tagged "Sjogren’s syndrome and salivary hypofunction"

Abstract Number: 530 • ACR/ARHP Annual Meeting 2014
Downregulation of Microrna-183 in Sjogren’s Syndrome Minor Salivary Glands. Implications in Control of Ezrin Expression and Salivary Gland Function
Paola Perez Riveros¹, Mayank Tandon¹, Salman Kazmi², Alessia Gallo², Gabor G. Illei³ and Ilias Alevizos⁴, ¹Sjogren's Clinic, NIDCR, Bethesda, MD, ²NIH, Bethesda, MD, ³Sjogren's Clinic, NIDCR/ NIH, Bethesda, MD, ⁴Sjogren's Clinic, NIDCR/ NIH #10 1N110, Bethesda, MD
Background/Purpose Sjogren’s syndrome (SS) is an exocrinopathy, which is mainly characterized by salivary glands (SG) hypofunction. SGs from SS patients present dilated lumen in acini…
Abstract Number: 529 • ACR/ARHP Annual Meeting 2014
IP3R3 Deficit Underlies the Loss of Fluid Secretion in Salivary Glands from Sjögren’s Syndrome Patients
Leyla Y Teos¹, Bill Swaim², Margaret Grisius³, Ana Paola Cotrim¹, Shyh-Ing Jang⁴, Lolita Bebris³, David Yule⁵, Gabor G. Illei⁶, Indu Ambudkar⁷ and Ilias Alevizos⁸, ¹NIDCR, NIH, Bethesda, MD, ²Mptb, NIH/NIDCR, Bethesda, MD, ³NIH, Bethesda, MD, ⁴Molecular Physiology and Therapeutics Branch, NIDCR, Bethesda, MD, ⁵Pharmacology and Physiology,, University of Rochester, Rpochester, NY, ⁶Sjogren's Clinic, NIDCR/ NIH, Bethesda, MD, ⁷NIDCR, MPTB, NIH, Bethesda, MD, ⁸Sjogren's Clinic, NIDCR/ NIH #10 1N110, Bethesda, MD
Background/Purpose Sjögren’s syndrome (SS) is a chronic autoimmune disease with unknown etiology. Affecting from 0.2% to 3.0% of the total population, with a 9:1 female…