Abstracts tagged "Sjogren’s syndrome and polymorphism"

Abstract Number: 2090 • ACR/ARHP Annual Meeting 2014
Contribution of MTHFR Gene Polymorphisms in Sjogren’s Syndrome Related Lymphomagenesis
Sofia Fragkioudaki¹, Adrianos Nezos², Aristea Papageorgiou³, Michael Voulgarelis³, Mary K. Crow⁴, Haralampos M. Moutsopoulos³ and Clio Mavragani¹, ¹Department of Physiology, School of Medicine, University of Athens, Athens, Greece, ²Department of Physiology, School of Medicine, University of Athens, Athens, Greece, ³Department of Pathophysiology, School of Medicine, University of Athens, Athens, Greece, ⁴Department of Medicine, Hospital for Special Surgery, New York, NY
Background/Purpose: Sjogren’s syndrome (SS) exhibits the highest susceptibility, among systemic autoimmune diseases, to non-Hodgkin lymphoma (NHL) development. Genetic instability and DNA methylation have been previously…