ACR Meeting Abstracts

ACR Meeting Abstracts

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Abstracts tagged "Sjogren’s syndrome and interferons"

  • Abstract Number: 1073 • 2017 ACR/ARHP Annual Meeting

    Aberrant Cell Signaling in Peripheral Blood Mononuclear Cells upon Interferon Alpha Stimulation in Patients with Primary Sjögren’s Syndrome Associates with Type I Interferon Signature

    Richard Davies1, Daniel Hammenfors1,2, Brith Bergum1, Petra Vogelsang1, Sonia Gavasso3, Johan G. Brun2,4, Roland Jonsson5,6 and Silke Appel1, 1Broegelmann Research Laboratory, Department of Clinical Science, University of Bergen, Bergen, Norway, 2Department of Rheumatology, Haukeland University Hospital, Bergen, Norway, 3Department of Neurology, Haukeland University Hospital, Bergen, Norway, 4Department of Clinical Science, University of Bergen, Bergen, Norway, 5Broegelmann Research laboratory, Department of Clinical Science, University of Bergen, Bergen, Norway, 6Department of Rheumatology, Haukeland University Hospital, Bergen, Bergen, Norway

    Background/Purpose: Primary Sjögren’s syndrome (pSS) is a complex heterogeneous systemic autoimmune disease. Biomarkers for patient stratification are scarce. Several single nucleotide polymorphisms within type I…
  • Abstract Number: 3034 • 2016 ACR/ARHP Annual Meeting

    A Selective JAK1 Inhibitor, Filgotinib Suppresses Lymphocytic Infiltration in Salivary Gland of Non Obese Diabetic Mice Via Suppression of BAFF and Chemokine Production of Salivary Gland Epithelial Cells

    Jennifer Lee1, Seo Hwa Kim2, Haneul Kim3, Seung-Ki Kwok4, Ji Hyeon Ju5 and Sung-Hwan Park5, 1Division of Rheumatology, Department of Internal Medicine, College of Medicine, The Catholic University of Korea, Seoul, Korea, Republic of, 2Division of Rheumatology,, Division of Rheumatology, Department of Internal Medicine, College of Medicine, The Catholic University of Korea, Seoul, Korea, The Republic of, 3Division of Rheumatology, Department of Internal Medicine, College of Medicine, The Catholic University of Korea, Seoul, Korea, The Republic of, 4seungki73@catholic.ac.kr, Division of Rheumatology, Department of Internal Medicine, College of Medicine, The Catholic University of Korea, Seoul, South Korea, 5Division of Rheumatology, Department of Internal Medicine, College of Medicine, The Catholic University of Korea, Seoul, South Korea

    Background/Purpose:  Interferon(IFN) signatures are upregulated in patients with primary Sjogren’s syndrome (pSS) and interferons are considered to play a pathogenic role in pSS. Therefore, Janus…
  • Abstract Number: 1054 • 2015 ACR/ARHP Annual Meeting

    A Potential Role of Type III Interferon in the Glandular Involvement of Sjögren’s Syndrome

    Tania Mora1, Felipe Alonso Masso Rojas2, Araceli Paez2, Mariana Patlan3, Misael Gómez-Mondragón2, Alberto Aranda-Frausto4, Maya Chacón Pérez5 and Luis M. Amezcua-Guerra6,7, 1Rheumatology, National Institute of Cardiology, Mexico City, Mexico, 2Department of Cell Physiology, National Institute of Cardiology, Mexico City, Mexico, 3Department of Immunology, National Institute of Cardiology, Mexico City, Mexico, 4Department of Pathology, National Institute of Cardiology, Mexico City, Mexico, 5National Institute of Cardiology, Mexico City, Mexico, 6Immunology, National Institute of Cardiology, Mexico City, Mexico, 7Mexican Accreditation Council of Rheumatology, A.C., Mexico City, Mexico

    Background/Purpose: Primary Sjögren's syndrome (pSS) is an autoinmune disorder characterized by lymphocytic infiltration of salivary and lachrymal glands. Recently, it has been showed that plasmacytoid…
  • Abstract Number: 1047 • 2014 ACR/ARHP Annual Meeting

    Type I and II Interferon Signatures in Sjogren’s Syndrome: Contributions in Distinct Clinical Phenotypes and Sjogren’s Related Lymphomagenesis

    Adrianos Nezos1, Fotini Gravani2, Efstathia K. Kapsogeorgou3, Michael Voulgarelis4, Haralampos M. Moutsopoulos4, Mary K. Crow5 and Clio Mavragani6, 1Department of Physiology, School of Medicine, University of Athens, Athens, Greece, 2Department of Rheumatology, General Hospital of Athens "G.Gennimatas", Athens, Greece, 3Pathophysiology, School of Medicine, National University of Athens, Greece, Athens, Greece, 4Department of Pathophysiology, School of Medicine, University of Athens, Athens, Greece, 5Department of Medicine, Hospital for Special Surgery, New York, NY, 6Department of Physiology, School of Medicine, University of Athens, Athens, Greece

    Background/Purpose: Both type I and II interferons (IFNs) have been implicated in the pathogenesis of Sjogren’s syndrome (SS). We aimed to explore the contribution of…
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ACR Convergence: Where Rheumatology Meets. All Virtual. November 5-9.

ACR Pediatric Rheumatology Symposium 2020

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