Abstracts tagged "Sjogren’s syndrome and inflammasome activation"

Abstract Number: 3030 • ACR/ARHP Annual Meeting 2016
Evidence of Inflammasome Activation in the Peripheral Blood and Salivary Gland Tissues of Primary Sjögren’s Syndrome Patients: Correlation with Clinical Indices of Severe Disease and Lymphoma Development
Aglaia G Vakrakou^1,2, Sorina Boiu^3,4 and Menelaos N Manoussakis^1,5, ¹Hellenic Pasteur Institute, Athens, Greece., Hellenic Pasteur Institute, Athens, Greece, Athens, Greece, ²Department of Pathophysiology, Department of Pathophysiology, School of Medicine, University of Athens, Greece, Athens, Greece, ³Department of Pathophysiology, School of Medicine, University of Athens, Greece, Athens, Greece, ⁴Hellenic Pasteur Institute, Athens, Greece, Athens, Greece, ⁵Department of Pathophysiology, School of Medicine, University of Athens, Greece, Department of Pathophysiology, School of Medicine, University of Athens, Greece, Athens, Greece
Background/Purpose: Inflammasomes are intracellular multiprotein complexes that sense pathogenic microorganisms, as well as danger signals released following tissue injury. Such activation of inflammasome leads to…