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Abstracts tagged "Sjogren’s syndrome and hydroxychloroquine"

  • Abstract Number: L10 • 2018 ACR/ARHP Annual Meeting

    Clinical Efficacy of Leflunomide/Hydroxychloroquine Combination Therapy in Patients with Primary Sjogren’s Syndrome: Results of a Placebo-Controlled Double-Blind Randomized Clinical Trial

    Timothy R.D.J. Radstake1, Eefje H.M. van der Heijden2, Frederique M. Moret3, Maarten R. Hillen4, Ana P. Lopes5, Toine Rosenberg6, Nard Janssen6, Aike A. Kruize7 and Joel A.G. van Roon3, 1Department of Rheumatology & Clinical Immunology, University Medical Center Utrecht, Utrecht, Netherlands, 2Department of Rheumatology and Clinical Immunology, Laboratory of Translational Immunology, University Medical Center Utrecht, Utrecht, Netherlands, 3Rheumatology & Clinical Immunology/ Laboratory of Translational Immunology, University Medical Center Utrecht, Utrecht, Netherlands, 4Rheumatology & Clinical Immunology, University Medical Center Utrecht, Utrecht, Netherlands, 5Laboratory of Translational Immunology, University Medical Center Utrecht, Utrecht, Netherlands, 6Department of Oral-Maxillofacial Surgery, University Medical Center Utrecht, Utrecht, Netherlands, 7Department of Rheumatology and Clinical Immunology, University Medical Center Utrecht, Utrecht, Netherlands

    Background/Purpose: Primary Sjogren’s syndrome (pSS) is a systemic, progressive autoimmune disease characterized by secretory gland dysfunction which lacks effective therapy. Clinical trials in patients with…
  • Abstract Number: 2674 • 2016 ACR/ARHP Annual Meeting

    Primary Sjögren’s Syndrome: Extraglandular Manifestations and Hydroxychloroquine Therapy

    Julia Demarchi1, Silvia Beatriz Papasidero2, María Alejandra Medina3, Diana Klajn4, Rafael Chaparro del Moral2, Oscar Luis Rillo5, María Victoria Martire6, Gloria Crespo7, Anastasia Secco8, Antonio Catalan Pellet6, Cristina Amitrano9, Catherine Crow10, Cecilia Asnal9, Paula Pucci9, Francisco Caeiro11, Nadia Benzaquén11, Juan Pablo Pirola11, Marcela Colazo11, M. Mayer12, F. Zazzetti12, S. Velez12, J. C. Barreira13, Natalia Tamborenea14, M. L. Santiago14 and Laura Raiti15, 1Rheumatology Deparment, Hospital General de Agudos Dr. Enrique Tornú, Buenos Aires, Argentina, 2Rheumatology Department, Rheumatology Unit, Hospital General de Agudos Dr. E. Tornú, Buenos Aires, Argentina, 3Rheumatology Department, Hospital General de Agudos Dr. Enrique Tornú, Buenos Aires, Argentina, 4Research Committee, Research Committee, Hospital General de Agudos Dr. E. Tornú, Buenos Aires, Argentina, 5Rheumatology Department, Hospital General de Agudos “Dr. Ignacio Pirovano”, Buenos Aires, Argentina, Buenos Aires, Argentina, 6Rheumatology, Hospital Bernardino Rivadavia, Buenos Aires, Argentina, 7Hospital Bernardino Rivadavia, Ciudad Autónoma de Buenos Aires, Argentina, 8Hospital Bernardino Rivadavia, Buenos Aires, Argentina, 9Rheumatology, Hospital Alemán, Buenos Aires, Argentina, 10Rheumatology, Hospital Alemán, Buenos aires, Argentina, 11Rheumatology, Hospital Privado Centro Médico de Córdoba, Córdoba, Argentina, 12Hospital Británico, Buenos Aires, Argentina, 13Rheumatology Service, Hospital Británico, Buenos Aires, Buenos Aires, Argentina, 14Rheumatology, OMI, Buenos Aires, Argentina, 15Clínica Bessone, San Miguel, Argentina

    Background/Purpose: The use of Hydroxychloroquine (HCQ) in Primary Sjögren's Syndrome (PSS) has been assessed in different studies over the last years, with conflicting results regarding…
  • Abstract Number: L9 • 2012 ACR/ARHP Annual Meeting

    Inefficacy of Hydroxychoroquine in Primary Sjögren’s Syndrome: Results of the Joquer Randomized Placebo-Controlled Trial in Primary Sjögren’s Syndrome

    Jacques-Eric Gottenberg1, Philippe Ravaud2, Xavier Puechal3, Véronique Le Guern4, Jean Sibilia5, Vincent Goeb6, C. Larroche7, JJ Dubost8, Stephanie RIST9, Alain Saraux10, Jacques Morel11, Gilles Hayem12, Eric Hachulla13, Aleth Perdriger14, D. Sene14, Charles Zarnitsky15, Elodie Perrodeau16, D. Batouche17, V. Furlan18, Joelle Benessiano19, Raphaèle Seror20 and Xavier Mariette18, 1Strasbourg University Hospital, Strasbourg, France, 2Epidemiology, Hopital Hotel Dieu, Paris Descartes University, Paris, France, 3Internal Medicine, Hôpital Cochin, Paris, France, 4Department of Internal Medicine, Cochin Hospital, Paris, France, 5Rheumatology, CHU Hautepierre, Strasbourg, France, 6Rheumatology, Rouen University Hospital, Rouen, France, 7Hospital University Bobigny, bobigny, France, 8Rheumatology, CHU CLERMONT-FERRAND, Clermont-Ferrand, France, 9Orleans, Rhumatologie, 10Department of rheumatology and unit of immunology (EA 2216), Université Brest Occidentale, Brest, France, 11Dpartment of Rheumatology, Lapeyronie Hospital, Montpellier, France, 12Rheumatology Unit, Bichat Hospital, Paris, France, 13Department of Internal Medicine, Claude Huriez University Hospital, Lille, France, 14Rheumatology, Hôpital Sud, Rennes, France, 15Rheumatology, Le Havre General Hospital, Le Havre, France, 16Epidemiologist, Paris, France, 17Paris, 18Rheumatology, Université Paris-Sud, Le Kremlin Bicetre, France, 19Rheumatology, Paris Unervisity Hospital BICHAT, Paris, France, 20Rheumatology, Bicetre university hospital, LE Kremlin-Bicetre, France

    Background/Purpose: Hydroxychloroquine (HQ, Plaquenil) is often prescribed in patients with primary Sjögren’s syndrome (pSS), notably for arthralgias, synovitis or purpura, but also only for dryness…
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