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Abstracts tagged "Sjogren’s syndrome and genomics"

  • Abstract Number: 524 • ACR/ARHP Annual Meeting 2012

    RNA-Sequencing Identifies Novel Differentially Expressed Coding and Non-Coding Transcripts in Sjögren’s Syndrome

    Indra Adrianto1, Graham B. Wiley1, John A. Ice1, He Li1, Jennifer A. Kelly2, Astrid Rasmussen1, Stuart B. Glenn3, Kimberly Hefner4, Donald U. Stone5, Raj Gopalakrishnan6, Glen D. Houston7, David M. Lewis8, Michael Rohrer6, James A. Lessard9, Juan-Manuel Anaya10, Barbara M. Segal11, Nelson L. Rhodus12, Lida Radfar13, John B. Harley14, Judith A. James2, Courtney G. Montgomery1, R. Hal Scofield15, Patrick M. Gaffney1, Kathy Moser Sivils2 and Christopher J. Lessard16, 1Arthritis and Clinical Immunology Research Program, Oklahoma Medical Research Foundation, Oklahoma City, OK, 2Oklahoma Medical Research Foundation, Oklahoma City, OK, 3Arthritis and Clinical Immunology, Oklahoma Medical Research Foundation, Oklahoma City, OK, 4Hefner Eye Care and Optical Center, Oklahoma City, OK, 5Ophthalmology, University of Oklahoma Health Sciences Center, Oklahoma City, OK, 6Diagnostic and Biological Sciences, University of Minnesota, Minneapolis, MN, 7Collage of Denistry, University of Oklahoma Health Sciences Center, Oklahoma City, OK, 8College of Dentistry, University of Oklahoma Health Sciences Center, Oklahoma City, OK, 9Valley Bone and Joint Clinic, Grand Forks, ND, 10School of Medicine and Health Sciences, Universidad del Rosario. Center for Autoimmune Diseases Research (CREA), Bogotá, Colombia, 11Rheumatology, Hennepin County Medical Center, Minneapolis, MN, 12University of Minnesota, Minneapolis, MN, 13University of Oklahoma Health Sciences Center, Oklahoma City, OK, 14Division of Rheumatology and The Center for Autoimmune Genomics & Etiology, University of Cincinnati, Cincinnati Children's Hospital Medical Center; US Department of Veterans Affairs Medical Center, Cincinnati, OH, 15Arthritis and Clinical Immunology Program, Oklahoma Medical Research Foundation, Oklahoma City, OK, 16Arthritis and Clinical Immunology Research Program, Oklahoma Medical Research Foundation; University of Oklahoma Health Sciences Center, Oklahoma City, OK

    Background/Purpose: Sjögren’s syndrome (SS) is a common, clinically heterogeneous autoimmune disease characterized by exocrine gland dysfunction that involves both innate and adaptive immune responses.  SS…

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