Abstracts tagged "Sjogren’s syndrome and genomics"

Abstract Number: 524 • 2012 ACR/ARHP Annual Meeting
RNA-Sequencing Identifies Novel Differentially Expressed Coding and Non-Coding Transcripts in Sjögren’s Syndrome
Indra Adrianto¹, Graham B. Wiley¹, John A. Ice¹, He Li¹, Jennifer A. Kelly², Astrid Rasmussen¹, Stuart B. Glenn³, Kimberly Hefner⁴, Donald U. Stone⁵, Raj Gopalakrishnan⁶, Glen D. Houston⁷, David M. Lewis⁸, Michael Rohrer⁶, James A. Lessard⁹, Juan-Manuel Anaya¹⁰, Barbara M. Segal¹¹, Nelson L. Rhodus¹², Lida Radfar¹³, John B. Harley¹⁴, Judith A. James², Courtney G. Montgomery¹, R. Hal Scofield¹⁵, Patrick M. Gaffney¹, Kathy Moser Sivils² and Christopher J. Lessard¹⁶, ¹Arthritis and Clinical Immunology Research Program, Oklahoma Medical Research Foundation, Oklahoma City, OK, ²Oklahoma Medical Research Foundation, Oklahoma City, OK, ³Arthritis and Clinical Immunology, Oklahoma Medical Research Foundation, Oklahoma City, OK, ⁴Hefner Eye Care and Optical Center, Oklahoma City, OK, ⁵Ophthalmology, University of Oklahoma Health Sciences Center, Oklahoma City, OK, ⁶Diagnostic and Biological Sciences, University of Minnesota, Minneapolis, MN, ⁷Collage of Denistry, University of Oklahoma Health Sciences Center, Oklahoma City, OK, ⁸College of Dentistry, University of Oklahoma Health Sciences Center, Oklahoma City, OK, ⁹Valley Bone and Joint Clinic, Grand Forks, ND, ¹⁰School of Medicine and Health Sciences, Universidad del Rosario. Center for Autoimmune Diseases Research (CREA), Bogotá, Colombia, ¹¹Rheumatology, Hennepin County Medical Center, Minneapolis, MN, ¹²University of Minnesota, Minneapolis, MN, ¹³University of Oklahoma Health Sciences Center, Oklahoma City, OK, ¹⁴Division of Rheumatology and The Center for Autoimmune Genomics & Etiology, University of Cincinnati, Cincinnati Children's Hospital Medical Center; US Department of Veterans Affairs Medical Center, Cincinnati, OH, ¹⁵Arthritis and Clinical Immunology Program, Oklahoma Medical Research Foundation, Oklahoma City, OK, ¹⁶Arthritis and Clinical Immunology Research Program, Oklahoma Medical Research Foundation; University of Oklahoma Health Sciences Center, Oklahoma City, OK
Background/Purpose: Sjögren’s syndrome (SS) is a common, clinically heterogeneous autoimmune disease characterized by exocrine gland dysfunction that involves both innate and adaptive immune responses. SS…

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