Abstracts tagged "Sjogren’s syndrome and dendritic cells"

Abstract Number: 658 • ACR/ARHP Annual Meeting 2016
Decreased Expression of Ten Micro-RNAs in Plasmacytoid Dendritic Cells of Patients with Primary SS Indicates Dysregulation on Multiple Levels
Maarten R. Hillen^1,2, Sofie L.M. Blokland^1,2, Elena Chouri^1,2, Aike A. Kruize¹, Marzia Rossato^1,2, Joel A.G. van Roon^1,2 and Timothy R.D.J. Radstake^1,2, ¹Department of Rheumatology & Clinical Immunology, UMC Utrecht, Utrecht, Netherlands, ²Laboratory of Translational Immunology, UMC Utrecht, Utrecht, Netherlands
Background/Purpose: Plasmacytoid dendritic cells (pDCs) are indicated to be key players in the pathogenesis of primary Sjögren’s syndrome (pSS) and important producers of type-1 interferon…
Abstract Number: 3232 • ACR/ARHP Annual Meeting 2016
Decreased Expression of Micro-RNA 130a and Micro-RNA 708 in Type-1 Classical Dendritic Cells of Patients with Primary SS Indicates Their Dysregulation
Maarten R. Hillen^1,2, Sofie L.M. Blokland^1,2, Elena Chouri^1,2, Ana Lopes^1,2, Aike A. Kruize², Marzia Rossato^1,2, Timothy R.D.J. Radstake^1,2 and Joel A.G. van Roon^1,2, ¹Laboratory of Translational Immunology, UMC Utrecht, Utrecht, Netherlands, ²Department of Rheumatology & Clinical Immunology, UMC Utrecht, Utrecht, Netherlands
Background/Purpose: cDespite the fact that especially cDC1s are candidate key players in the activation of local T and B-cells in pSS, they have rarely been…