Abstracts tagged "Sjӧgrens and autoantibodies"

Abstract Number: 576 • 2017 ACR/ARHP Annual Meeting
Immunosignature-Based Diagnosis and Prediction of Therapeutic Response Enables Retrospective Patient Stratification in a Phase IIa Clinical Trial for VAY736 in Primary Sjögren’s Syndrome
Robert Gerwien¹, Theodore M. Tarasow², Jonathan Melnick², Anna Lei³, Arvind Kinhikar⁴, Julie Doucet⁵, Remi Kazma⁵, Paul Maguire⁴, Irina Koroleva⁶, Giulio Macchiarella⁴, Alexandre Avrameas⁵, Marie-Anne Valentin⁵, Stephen Oliver⁵ and Alessandra Vitaliti⁵, ¹HealthTell, Inc, san ramon, CA, ²HealthTell, Inc., San Ramon, CA, ³Health Tell, San Ramon, CA, ⁴Novartis, Cambridge, MA, ⁵Translational Medicine, Novartis Institutes for Biomedical Research, Basel, Switzerland, ⁶Novartis Institutes for BioMedical Research, Novartis Pharma AG, Cambridge, MA
Background/Purpose: Although patient stratification can improve the success rate of clinical trials, efforts to apply this strategy to autoimmune studies such as Sjögren’s syndrome are…

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