Abstracts tagged "single cell rna seq"

Abstract Number: 2809 • 2019 ACR/ARP Annual Meeting
Single-Cell RNA Sequencing of Murine Neutrophils Identifies a Transcriptional Continuum (“Neutrotime”) Across Biological Compartments
Ricardo Grieshaber-Bouyer¹, Giuseppina Stifano ², Pierre Cunin ³, Anaïs Levescot ⁴, Nathan Nelson-Maney ⁴, Rachel Blaustein ⁵, Paul Monach ⁶, Peter Nigrovic ⁷ and ImmGen Consortium ⁸, ¹Department of Medicine, Division of Rheumatology, Immunology and Allergy, Brigham and Women’s Hospital, Harvard Medical School, Boston, MA, USA; Department of Orthopedics, Heidelberg University Hospital, Heidelberg, Germany, Boston, MA, ²Department of Medicine, Division of Rheumatology, Immunology and Allergy, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA, Boston, ³Department of Medicine, Division of Rheumatology, Immunology and Allergy, Brigham and Women’s Hospital, Harvard Medical School, Boston, MA, ⁴Division of Rheumatology, Immunology and Allergy, Brigham and Women’s Hospital, Boston, MA, ⁵Brigham and Women's Hospital, Boston, ⁶Brigham and Women's Hospital, Boston, MA, ⁷Department of Medicine, Division of Rheumatology, Immunology and Allergy, Brigham and Women’s Hospital, Harvard Medical School, Boston, MA, USA ; Department of Medicine, Division of Immunology, Boston Children’s Hospital, Harvard Medical School, Boston, MA, USA., Boston, ⁸Harvard Medical School, Boston
Background/Purpose: Neutrophils are key first responders of innate immunity, participating in both defense and inflammatory disease. Phenotypic heterogeneity is recognized but the existence of bone…

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