signal transduction and transforming growth factor Archives

Abstract Number: 23 • ACR/ARHP Annual Meeting 2012
Differential Effects of Bone Morphogenetic Protein 2 and 9 On Chondroprotective Transforming Growth Factor β Signaling
Arjan P. van Caam¹, Esmeralda N. Blaney Davidson¹, Elly L. Vitters², Laurie de Kroon¹, Ellen W. van Geffen³, Peter ten Dijke⁴, Wim B. van den Berg² and Peter M. van der Kraan², ¹Rheumatology Research & Advanced Therapeutics, Radboud University Nijmegen Medical Centre, Nijmegen, Netherlands, ²Rheumatology Research and Advanced Therapeutics, Radboud University Nijmegen Medical Centre, Nijmegen, Netherlands, ³Experimental Rheumatology, Radboud university medical center, Nijmegen, Netherlands, ⁴Department of Molecular Cell Biology, Leiden University Medical Center, Leiden, Netherlands
Background/Purpose: Osteoarthritis (OA) is a multifactorial disease characterized by loss of articular cartilage. TGFβ is considered as a protective factor against cartilage loss in young cartilage…

Abstracts tagged "signal transduction and transforming growth factor"