Abstracts tagged "signal transduction and spondylarthritis"

Abstract Number: 2702 • ACR/ARHP Annual Meeting 2016
Taking Fly for Understanding the Molecular Role of HLA-B27/hB2m in Spondyloarthritis
Nadège Jah¹, Benjamin Grandon², Aurore Rincheval-Arnold³, Isabelle Guénal³, Sébastien Gaumer³, Claudine André⁴, Maxime A. Breban⁵ and Gilles Chiocchia^6,7, ¹Infection and inflammation, INSERM UMR1173, Montigny-le-Bretonneux, France, ²Inserm UMR 1173 and LGBC, 78180 Saint Quentin en Yvelines, France, ³Laboratory of Genetic and Cellular Biology, Faculty of Health Sciences Simone Veil, Montigny-le-Bretonneux,, 78180 SAINT QUENTIN EN YVELINES, France, ⁴UMR 1173, 78180 Saint-Quentin en Yvelines, France, ⁵Rheumatology Division, Ambroise Paré Hospital (AP-HP), and Versailles Saint Quentin en Yvelines University, Boulogne-Billancourt, France, ⁶Infection and Inflammation, INSERM-U1173, University of Versailles Saint-Quentin-en-Yvelines, France, Montigny-le-Bretonneux, France, ⁷Service d'Immunologie, Ambroise Paré Hospital, University of Versailles Saint-Quentin-en-Yvelines, Boulogne, France, Boulogne-Billancourt, France
Background/Purpose: After more than 40 years of researches, the mechanisms underlying the association of HLA-B27 with spondyloarthritis (SpA) remain poorly understood. The Drosophila has been…