Abstracts tagged "scleroderma and statins"

Abstract Number: 1508 • 2012 ACR/ARHP Annual Meeting
Simvastatin Attenuates Pulmonary Fibrosis in a Murine Model of Systemic Sclerosis
Gianluca Bagnato¹, Alessandra Bitto², Natasha Irrera², Gabriele Pizzino², Donatella Sangari¹, Maurizio Cinquegrani³, Neal Roberts⁴, Gianfilippo Bagnato¹, Francesco Squadrito² and Antonino Saitta³, ¹Rheumatology, University of Messina, Messina, Italy, ²Pharmacology, University of Messina, Messina, Italy, ³Internal Medicine, University of Messina, Messina, Italy, ⁴Medical College of Virginia, Richmond, VA
Background/Purpose: Simvastatin is best known for its antilipidemic action due to its inhibition of 3-hydroxy-3-methylglutaryl CoenzymeA (HMG CoA) reductase. Inhibition of biological precursors in this pathway also…

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Abstracts tagged "scleroderma and statins"

Simvastatin Attenuates Pulmonary Fibrosis in a Murine Model of Systemic Sclerosis