ACR Meeting Abstracts
Abstract Number: 674 • ACR/ARHP Annual Meeting 2016
Gwenny M. Verstappen1, Hendrik L.F. Broekman1, Erlin A. Haacke2, Petra M. Meiners3, Fred K.L. Spijkervet3, Arjan Vissink4, Hendrika Bootsma5 and Frans G.M. Kroese1, 1Rheumatology and Clinical Immunology, University of Groningen, University Medical Center Groningen, Groningen, Netherlands, 2Pathology and Medical Biology, University of Groningen, University Medical Center Groningen, Groningen, Netherlands, 3Oral and Maxillofacial Surgery, University of Groningen, University Medical Center Groningen, Groningen, Netherlands, 4Department of Oral and Maxillofacial Surgery, University of Groningen, University Medical Center Groningen, Groningen, Netherlands, 5Rheumatology and Clinical Immunology, University of Groningen, University Medical Center Groningen, The Netherlands, Groningen, Netherlands
Background/Purpose: Interleukin-21 plays a central role in plasma cell differentiation and germinal center (GC) formation and is likely involved in the pathogenesis of primary Sjögren’s…