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Abstracts tagged "ROS and toll-like receptors"

  • Abstract Number: 772 • ACR/ARP Annual Meeting 2019

    The Study of the Novel G87V Mutation in the TNFRSF1A Gene Identified in a Family with TNF Receptor-Associated Periodic Syndrome (TRAPS)

    Shoko Tsuji1, Hidenori Matsuzaki 2, Masanori Iseki 3, Akiko Nagasu 1, Hiroyasu Hirano 1, Katsuhiko Ishihara 4, Naoyasu Ueda 5, Yoshitaka Honda 6, Takahiko Horiuchi 7, Ryuta Nishikomori 8, Yoshitaka Morita 1 and Tomoyuki Mukai 9, 1Department of Rheumatology, Kawasaki Medical School, Kurashiki, Okayama, Japan, 2Department of Life Sciences, Faculty of Life and Environmental Sciences, Prefectural University of Hiroshima, shobara, Hiroshima, Japan, 3Department of Immunology and Molecular Genetics, Kawasaki Medical School, Kurashiki, Okayama, Japan, 4Department of Immunology and Molecular Genetics, Kurashiki, Okayama, Japan, 5Department of Internal Medicine, Miyazaki Prefectural Miyazaki Hospital, Miyazaki, Japan, 6Department of Pediatrics, Kyoto University Graduate School of Medicine, Kyoto, Japan, 7Department of Internal Medicine, Kyushu University Beppu Hospital, Beppu, Japan, Beppu, Japan, 8Department of Pediatrics and Child Health, Kurume University School of Medicine, Kurume, Fukuoka, Japan, 9Department of Rheumatology, Kawasaki medical School, Kurashiki, Okayama, Okayama, Japan

    Background/Purpose: TNF Receptor-Associated Periodic Syndrome (TRAPS) is one of the autoinflammatory diseases. TRAPS is caused by heterozygous mutations in the TNFRSF1A gene. Although more than…

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