Abstracts tagged "ROS and systemic lupus erythematosus (SLE)"

Abstract Number: 2098 • ACR/ARHP Annual Meeting 2018
NRF2 Downregulates Inflammation and Protects Against Autoimmune Lung Disease in Experimental Lupus
Shuhong Han¹, Haoyang Zhuang¹, Pui Lee², Lijun Yang³ and Westley Reeves^1,4, ¹Medicine, University of Florida, Gainesville, FL, ²Harvard Medical School, Boston, MA, ³Pathology, Immunology and laboratory medicine, University of Florida, Gainesville, FL, ⁴Division of Rheumatology & Clinical Immunology, University of Florida, Gainesville, FL
Background/Purpose: The transcription factor nuclear factor erythroid 2-related factor (Nrf2) is a master regulator of genes involved in cellular defense against oxidative and electrophilic stresses.…