Abstracts tagged "rituximab and systemic sclerosis"

Abstract Number: 1110 • 2018 ACR/ARHP Annual Meeting
Characterization of CD20+ T Cells in Patients with Systemic Sclerosis
Monica D'Orazio¹, Elisabeth Fliesser², Florentine Moazedi-Fürst³, Martin Stradner⁴, Sonja Kielhauser³, Johannes Fessler⁵ and Hans-Peter Brezinschek¹, ¹Internal Medicine/Division of Rheumatoloy and Immunology, Rheumatology and Immunology, Medical University Graz, Austria, Graz, Austria, ²Div. of Rheumatology and Immunology, Medical University of Graz, Graz, Austria, ³Rheumatology and Immunology, Medical University Graz, Austria, Graz, Austria, ⁴Department of Rheumatology and Immunology, Medical University of Graz, Graz, Austria, ⁵Department of Neurology, Harvard Medical School, Boston, MA
Background/Purpose: Recently, it has been demonstrated that a subset of T cells expresses the B-cell marker CD20. It has been postulated that in rheumatoid arthritis…
Abstract Number: 1723 • 2018 ACR/ARHP Annual Meeting
Intensified B-Cell Depletion Therapy in Progressive Systemic Sclerosis Patients: 24 Months Follow-up
Daniela Rossi¹, Irene Cecchi², Massimo Radin³, Elena Rubini⁴, Savino Sciascia⁵ and Dario Roccatello⁶, ¹Department of Medicine and Experimental Oncology, CMID - Center of Research of Immunopathology and Rare Diseases, Turin, Italy, ²Center of Research of Immunopathology and Rare Diseases- Coordinating Center of Piemonte and Valle d’Aosta Network for Rare Diseases, Department of Clinical and Biological Sciences, University of Turin, Italy, Turin, Italy, ³Department of Clinical and Biological Sciences, Center of Research of Immunopathology and Rare Diseases- Coordinating Center of Piemonte and Valle d’Aosta Network for Rare Diseases, Department of Clinical and Biological Sciences, University of Turin, Italy, Turin, Italy, ⁴Center of Research of Immunopathology and Rare Diseases- Coordinating Center of Piemonte and Valle d’Aosta Network for Rare Diseases, Department of Clinical and Biological Sciences, University of Turin and S. Giovanni Bosco Hospital, Turin, Italy., Turin, Italy, ⁵Center of Research of Immunopathology and Rare Diseases- Coordinating Center of Piemonte and Valle d’Aosta Network for Rare Diseases, Department of Clinical and Biological Sciences, University of Turin, Italy, Center of Research of Immunopathology and Rare Diseases- Coordinating Center of Piemonte and Valle d’Aosta Network for Rare Diseases, Department of Clinical and Biological Sciences, University of Turin, Italy, Torino, Italy, ⁶Center of Research of Immunopathology and Rare Diseases- Coordinating Center of Piemonte and Valle d’Aosta Network for Rare Diseases, Department of Clinical and Biological Sciences, University of Turin and S. Giovanni Bo, Turin, Italy
Background/Purpose:Systemic sclerosis (SSc) is a connective tissue autoimmune disease with systemic involvement and a serious medical condition with a high rate of mortality, especially due…
Abstract Number: 2886 • 2017 ACR/ARHP Annual Meeting
Safety and Efficacy of Long-Time Intensified Rituximab Treatment in Patients with Systemic Sclerosis
Hans-Peter Brezinschek¹, Sonja Kielhauser², Winfried Graninger³ and Florentine Moazedi-Fürst², ¹Internal Medicine/Division of Rheumatoloy and Immunology, Rheumatology and Immunology, Medical University Graz, Austria, Graz, Austria, ²Rheumatology and Immunology, Medical University Graz, Austria, Graz, Austria, ³Rheumatology and Immunology, Medical University of Graz, Graz, Austria
Background/Purpose: Rituximab (RTX), a monoclonal B cell depleting antibody, is one of the few new drugs that has been shown to have beneficial effects on…
Abstract Number: 2894 • 2016 ACR/ARHP Annual Meeting
Efficacy of Rituximab in Systemic Sclerosis with Interstitial Lung Disease
Ahmet Mesut Onat¹, Orhan Zengin¹, Savas Aksoy¹, Mustafa Erkut Onder¹, Koray Gorkem Sacıntı² and Bunyamin Kisacik¹, ¹Rheumatology, Gaziantep University School of Medicine, Gaziantep, Turkey, ²Gaziantep University, School of Medicine, Gaziantep, Turkey
Background/Purpose: Systemic sclerosis (SSc) is a progressive fibrotic and autoimmune disease, which results to severe systemic complications. Rituximab (Rtx), an anti CD-20 antibody, has recently…
Abstract Number: 615 • 2015 ACR/ARHP Annual Meeting
Rituximab Non Responders Fail to Down Regulated CD19 on Naive B Cells
Hans-Peter Brezinschek¹, Florentine Fürst-Moazedi¹, Sonja Kielhauser², Martin Stradner³ and Winfried Graninger⁴, ¹Internal Medicine/Division of Rheumatology, Medical University Graz, Graz, Austria, ²Internal Medicine/Division of Rheumatology and Immunology, Medical University Graz, Graz, Austria, ³Department of Rheumatology and Immunology, Medical University Graz, Graz, Austria, ⁴Rheumatology and Immunology, Medical University of Graz, Graz, Austria
Background/Purpose: CD19 is a membrane glycoprotein of the immunoglobulin superfamily and part of the hetero-oligomeric complex comprising the complement receptor type 2, which positively regulates…
Abstract Number: 836 • 2015 ACR/ARHP Annual Meeting
Influence of B Cell Depletion By Monoclonal Anti CD20 Antibodies in Systemic Sclerosis: Results of a Randomized Placebo Controlled Trial
Samira Ben Said-Bouyeri¹, Jessica Meijs¹, Nina Ajmone Marsan², Anne A. Schouffoer¹, Maarten K. Ninaber³, Hans Ulrich Scherer⁴, Femke Bonte-Mineur⁵, T. W. J. Huizinga¹ and Jeska K. de Vries-Bouwstra¹, ¹Rheumatology, Leiden University Medical Center, Leiden, Netherlands, ²Cardiology, Leiden University Medical Center, Leiden, Netherlands, ³Pulmonology, Leiden University Medical Center, Leiden, Netherlands, ⁴Department of Rheumatology, Leiden University Medical Center, Leiden, Netherlands, ⁵Maasstad Hospital, Rotterdam, Rotterdam, Netherlands
Background/Purpose: Systemic sclerosis (SSc) is a severe, systemic auto-immune disease with limited treatment options. Previous observational studies showed possible efficacy of Rituximab (RTX), a monoclonal…

All abstracts accepted to ACR Convergence are under media embargo once the ACR has notified presenters of their abstract’s acceptance. They may be presented at other meetings or published as manuscripts after this time but should not be discussed in non-scholarly venues or outlets. The following embargo policies are strictly enforced by the ACR.

Accepted abstracts are made available to the public online in advance of the meeting and are published in a special online supplement of our scientific journal, Arthritis & Rheumatology. Information contained in those abstracts may not be released until the abstracts appear online. In an exception to the media embargo, academic institutions, private organizations, and companies with products whose value may be influenced by information contained in an abstract may issue a press release to coincide with the availability of an ACR abstract on the ACR website. However, the ACR continues to require that information that goes beyond that contained in the abstract (e.g., discussion of the abstract done as part of editorial news coverage) is under media embargo until 10:00 AM ET on November 14, 2024. Journalists with access to embargoed information cannot release articles or editorial news coverage before this time. Editorial news coverage is considered original articles/videos developed by employed journalists to report facts, commentary, and subject matter expert quotes in a narrative form using a variety of sources (e.g., research, announcements, press releases, events, etc.).

Violation of this policy may result in the abstract being withdrawn from the meeting and other measures deemed appropriate. Authors are responsible for notifying colleagues, institutions, communications firms, and all other stakeholders related to the development or promotion of the abstract about this policy. If you have questions about the ACR abstract embargo policy, please contact ACR abstracts staff at [email protected].