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Abstracts tagged "rituximab and abatacept"

  • Abstract Number: 2368 • ACR/ARP Annual Meeting 2019

    Risk of Diverticulitis and Gastro-Intestinal Perforation in Rheumatoid Arthritis Treated with Tocilizumab Compared to Rituximab and Abatacept: A Prospective Propensity-matched Cohort Study

    Claire Rempenault1, Cédric Lukas 1, Bernard Combe 2, Isabelle Pane 3, Xavier Mariette 4, Jacques-Eric Gottenberg 5 and Jacques Morel 1, 1Department of Rheumatology, Montpellier University Hospital, Montpellier, France, Montpellier, Languedoc-Roussillon, France, 2CHU Montpellier, Montpellier University, Montpellier, France, 3Centre de Recherche en Epidémiologie et Statistiques, INSERM U1153, Centre d'Épidémiologie Clinique, Hôpital Hôtel-Dieu, Assistance Publique-Hôpitaux de Paris (AP-HP), Descartes University, Paris, France., Paris, Ile-de-France, France, 4Center for Immunology of Viral Infections and Autoimmune Diseases, Assistance Publique – Hôpitaux de Paris, Hôpitaux Universitaires Paris-Sud, Le Kremlin-Bicêtre, Université Paris Sud, INSERM, Paris, France, 5Department of Rheumatology, Strasbourg University Hospital, Strasbourg, France

    Background/Purpose: Several studies have reported an increased risk of gastro-intestinal perforation (GIP) in rheumatoid arthritis (RA) patients treated with tocilizumab (TCZ) compared to conventional synthetic…

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