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Abstracts tagged "risk assessment"

  • Abstract Number: 2389 • ACR Convergence 2024

    Choroidal Thickness in Active Lupus Nephritis

    Leticia Maria Kolachinski R Brandao1, Lucas Parente de Andrade2, Débora Cordeiro do Rosário3, Paula Letícia De Queiroz e Barbosa4, Francisco Formiga3, Carolina Torres Ribeiro5, Tatiana do Nascimento Pedrosa3, Maria Fernanda Abalem de Sá Carricondo6, Pedro Carlos Carricondo2, Eloisa Bonfa3 and Michelle Remiao Ugolini Lopes3, 1Rheumatology Division, Hospital das Clinicas HCFMUSP, Faculdade de Medicina, Universidade de Sao Paulo, Sao Paulo, SP, Brazil, Campinas, SP, Brazil, 2Ophthalmology Division, Hospital das Clinicas HCFMUSP, Faculdade de Medicina, Universidade de Sao Paulo, Sao Paulo, SP, Brazil, São Paulo, SP, Brazil, 3Rheumatology Division, Hospital das Clinicas HCFMUSP, Faculdade de Medicina, Universidade de Sao Paulo, Sao Paulo, SP, Brazil, São Paulo, SP, Brazil, 4Ophthalmology Division, Hospital das Clinicas HCFMUSP, Faculdade de Medicina, Universidade de Sao Paulo, Sao Paulo, SP, Brazil, São Paulo, SP, 5Faculdade de Medicina, Universidade de Sao Paulo, São Paulo, SP, Brazil, 6Ophthalmology Division, Hospital das Clinicas HCFMUSP, Faculdade de Medicina, Universidade de Sao Paulo, São Paulo, SP, Brazil

    Background/Purpose: Lupus choroidopathy was reported to be a marker of severe systemic lupus erythematosus (SLE) activity, commonly associated with nephropathy. However, it remains controversial if…
  • Abstract Number: 0695 • ACR Convergence 2024

    Prognostic Value of Serum Type I Interferon in Predicting Morbi-Mortality Outcomes in Systemic Sclerosis: Insights from the STRIKE Basket Cohort

    Stefano Di Donato1, Marco Minerba2, Enrico De Lorenzis3, Collette Hartley4, Lesley-Anne Bissell5, Rebecca Ross6 and Francesco Del Galdo4, 1Leeds Institute of Rheumatic and Musculoskeletal Medicine, Chapel Allerton Hospital, Leeds, UK, Leeds, United Kingdom, 2Campus Bio-Medico University of Rome, Taranto, United Kingdom, 3Catholic University of the Sacred Heart, Roma, Rome, Italy, 4University of Leeds, Leeds, United Kingdom, 5Leeds Teaching Hospitals NHS Trust, Leeds, United Kingdom, 6Medicine and Health, University of Leeds, Leeds, United Kingdom

    Background/Purpose: Systemic Sclerosis (SSc) encompasses limited cutaneous (lc)SSc and diffuse cutaneous (dc)SSc, with lcSSc affecting more than 60% of patients and dcSSc associated being burdened…
  • Abstract Number: 1614 • ACR Convergence 2024

    Mortality in Patients with Giant Cell Arteritis in Spain: Results from the ARTESER Registry

    Juan Molina-Collada1, Marta Domínguez-Álvaro2, Rafael Benito Melero-Gonzalez3, Eugenio De Miguel4, Maite Silva-Diaz5, Jesús Alejandro Valero6, Ismael Gonzalez7, Julio Sánchez-Martín8, Javier Narvaez-García9, Joan Calvet10, Ivette Casafont-Solé11, José A Román Ivorra12, Selene Labrada-Arrabal13, Margarida Vasques Rocha:14, Carlota L Iñiguez:15, Maria Sagrario Bustabad Reyes16, Cristina Campos-Fernández17, María Alcalde Villar:18, Antonio Juan-Mas19 and Ricardo Blanco-Alonso20, and ARTESER Project Collaborative Group, 1Hospital General Universitario Gregorio Marañón, Madrid, Spain, 2Sociedad Española de Reumatología, Madrid, Spain, 3CHU Ourense, O Carballino, Spain, 4Hospital Universitario La Paz, Madrid, Spain, 5Complejo Hospitalario Universitario A Coruña, A Coruña, Spain, 6Hospital Universitario Donosti. Donostia, Spain, Donosti, Spain, 7Complejo Asistencial Universitario de Leon, León, Spain, 8Hospital Universitario 12 de Octubre, Madrid, Spain, 9Hospital Universitario de Bellvitge, Barcelona, Spain, 10Parc Taulí Hospital Universitari. Institut d'Investigació i Innovació Parc Taulí (I3PT-CERCA) (UAB), 08208 Sabadell, Spain, Barcelona, Spain, 11Hospital Universitari Germans Trias i Pujol, Badalona, Barcelona, Spain, Barcelona, Spain, 12Hospital Universitari i Politècnic La Fe, Valencia, Spain, Valencia, Spain, 13Hospital del Mar, Barcelona, Spain, 14Hospital Universitario Araba, Vitoria, Spain, 15Hospital Universitario Lucus Augusti, Galicia, Spain, Galicia, Spain, 16Hospital Universitario de Canarias, La Laguna - Tenerife, Spain, 17Consorci Hospital General Universitari de València, Comunitat Valenciana, Spain, Valencia, Spain, 18Hospital Universitario Severo Ochoa Leganés, Madrid, Spain, Madrid, Spain, 19Hospital Universitari Son Llàtzer, Mallorca, Spain, 20Division of Rheumatology, Hospital Universitario Marqués de Valdecilla. IDIVAL, Immunopathology group, Santander, Spain

    Background/Purpose: The question of survival in epidemiologic studies on giant cell arteritis (GCA) remains unclear to date, with notable heterogeneity in both the mortality rate…
  • Abstract Number: 2399 • ACR Convergence 2024

    Nationwide Analysis of Endovascular Thrombectomy in Ischemic Stroke Patients with Systemic Lupus Erythematosus and Rheumatoid Arthritis: Mortality and Healthcare Utilization

    Simran Bhimani1, Anand Maligireddy2, Shivang Chaudhary3, Yash Deshpande2, Kishan Patel4, Sameer Bhimani2, Shreyas Patel2 and Birju Bhatt5, 1The Wright Center for graduate medical education, Scranton, PA, 2The Wright Center, GME, Scranton, PA, 3Saint Louis University, St. Louis, MO, 4Riverside Community Hospital, Riverside, CA, 5Geisinger, Wilkes Barre, PA

    Background/Purpose: Ischemic stroke poses significant risks for patients with Systemic Lupus Erythematosus (SLE) and Rheumatoid Arthritis (RA), both conditions associated with heightened cardiovascular complications. Endovascular…
  • Abstract Number: 0141 • ACR Convergence 2024

    The Effect of Systemic Immunosuppressive Therapies on Cardiovascular Risk in Psoriatic Arthritis Patients

    Melody Esmaeili1, Linh Truong2, Nicole Ridolfi3, Eugenia Chen4 and Maida wong5, 1University of California, Irvine, Orange, CA, 2University of California, Los Angeles, Los Angeles, CA, 3University of California, Irvine, Newport Beach, CA, 4Long Beach VA Hospital, Irvine, CA, 5Long Beach VA Hospital, Los Angeles, CA

    Background/Purpose: Evidence demonstrates an increased prevalence of atherosclerotic cardiovascular disease (ASCVD) among psoriatic arthritis (PsA) patients. However, the relationship between immunosuppressive therapies and the development of ASCVD remains unclear.…
  • Abstract Number: 0721 • ACR Convergence 2024

    Does Serial ANCA Testing Help Predict the Risk of Relapse in Granulomatosis with Polyangiitis? A Single-center Cohort Study

    Xavier Puéchal1, Michele Iudici1, Elodie Perrodeau2, Claire Goulvestre3, Pascal cohen4, Alexis Régent1, Luc Mouthon5, Loïc Guillevin4, Raphael Porcher6 and Benjamin Terrier7, 1National Referral Center For Rare Systemic Autoimmune Diseases, Paris, France, 2Hôtel-Dieu, Paris, France, 3Laboratoire d'immunologie, Hôpital Cochin, AP-HP, Paris, Ile-de-France, France, 4National Referral Center For Rare Systemic Autoimmune Diseases, Paris, Ile-de-France, France, 5Service de Médecine Interne, Centre de Référence Maladies Systémiques Autoimmunes et Autoinflammatoires Rares d'Ile de France de l’Est et de l’Ouest, Hôpital Cochin, Assistance Publique-Hôpitaux de Paris (AP-HP), Paris, France, 6Department of Rheumatology, Bicêtre AP-HP Hôpital, Université Paris-Saclay, Paris, Ile-de-France, France, 7Service de Médecine interne, Hôpital Cochin, AP-HP, Paris, Ile-de-France, France

    Background/Purpose: ANCA-associated vasculitis (AAV) is a frequently relapsing disease for which a meta-analysis concluded that an increase or persistence of ANCA during remission is only…
  • Abstract Number: 1723 • ACR Convergence 2024

    Clustering Analysis with Unsupervised Machine Learning Process to Phenotype the Cardiovascular Risk of Patients with Rheumatoid Arthritis Beyond the 10-year Prediction Algorithm

    Fabio Cacciapaglia1, Vincenzo Venerito2, Gian Luca Erre3, Matteo Piga4, Andreina Manfredi5, Garifallia Sakellariou6, Ombretta Viapiana7, Elisa Gremese8, Elena Bartoloni Bocci9, Francesca Romana Spinelli10 and Fabiola Atzeni11, and "Cardiovascular Obesity and Rheumatic DISeases" Study Group of the Italian Society of Rheumatology, 1Rheumatology Unit DiMePRe-J, University and AOU Policlinico of Bari, Italy, Bari, Italy, 2Rheumatology Unit, DiMePRe-J University of Bari, Bari, Italy, 3Rheumatology Unit - University of Sassari, Sassari, Italy, 4Rheumatology Unit - University of Cagliari, Cagliari, Italy, 5University of Modena and Reggio Emilia, Modena, 6Department of Internal Medicine and Medical Therapy, University of Pavia, and Istituti Clinici Scientifici Maugeri IRCCS Pavia,, Pavia, Italy, 7Rheumatology Unit, University of Verona, Verona, Italy, 8Catholic University of the Sacred Heart, Rome, Rome, Italy, 9Rheumatology Unit. Department of Medicine, Perugia, Perugia, Italy, 10Sapienza University of Rome, Rome - Italy, Roma, Rome, Italy, 11University of Messina, Italy, Messina, Italy

    Background/Purpose: Rheumatoid arthritis (RA) patients are at increased cardiovascular (CV) risk, but traditional CV risk factors and available 10-year CV risk estimation models may not…
  • Abstract Number: 2418 • ACR Convergence 2024

    Identification of Co-expressed Molecular Markers That Predict Risk of Severe Flare in Patients with Systemic Lupus Erythematosus (SLE)

    Matthew Linnik1, Guilherme Rocha2, David Gemperline3, Ernst Dow3, Christoph Preuss3, Helen Masson4, Olivia Ellis4, Ana Accioly3, Maja Hojnik5, Kira Rubtsova1, Robert Benschop6, Mark Chambers7, Mark Genovese3 and Richard Higgs3, 1Eli Lilly, San Diego, CA, 2Eli Lilly, Indianapolis, IN, 3Eli Lilly and Co, Indianapolis, IN, 4Eli Lilly and Co, San Diego, CA, 5Eli Lilly and Co., Indianapolis, IN, 6Eli Lilly and Company, Indianapolis, IN, 7Eli Lilly, Zionsville, IN

    Background/Purpose: SLE flare is a clinically and regulatory relevant outcome, yet limited markers currently exist that predict its risk. We used baseline whole blood/serum samples…
  • Abstract Number: 0209 • ACR Convergence 2024

    Characteristics of Ordering Providers and Patients with Positive Antinuclear Antibodies: A Pragmatic, Risk Model Study

    Emily Grace, Sarah Green, Nikol Nikolova, Ashley Suh, Ryan Moore, Hank Domenico, Allison McCoy and April Barnado, Vanderbilt University Medical Center, Nashville, TN

    Background/Purpose: Positive antinuclear antibodies (ANAs) cause diagnostic dilemmas for clinicians across specialties. We previously developed and validated a risk model to predict risk of developing…
  • Abstract Number: 0851 • ACR Convergence 2024

    Diagnostic Ultrasound Enthesitis Tool (DUET) for Psoriatic Arthritis: The Distribution of Elementary Lesions Is Influenced by Site

    Lihi Eder1, Ricardo Acayaba de Toledo2, Fahmeen Afgani3, Catherine Bakewell4, Philippe Carron5, Basant Elnady6, Amir Haddad7, Arthur Kavanaugh8, Arnon Katz9, Minna Kohler10, josefina marin11, NZEUSSEU TOUKAP Adrien12, Marcos Rosemffet13, Ari Polachek14, Ernesto Rodriguez15, Ágnes Sarolta Szentpétery16, Abha Singh17, Maria S. Stoenoiu18, Ilaria Tinazzi19, Janeth Yinh10, Gurjit Kaeley20 and Sibel Aydin21, 1University of Toronto, Women’s College Hospital and Department of Medicine, Toronto, ON, Canada, 2FAMERP, São José do Rio Preto, Brazil, 3Women's College Hospital, Toronto, Canada, 4Intermountain Health Care, Salt Lake City, UT, 5UZ Gent, Gent, Belgium, 6Al Hada Forces Hospital, Rheumatology Department, Taif, Saudi Arabia, 7Carmel Medical Centre, Haifa, Israel, 8University of California San Diego, La Jolla, CA, 9GRAPPA - Patient Research Partner, Haifa, Israel, 10Massachusetts General Hospital, Boston, MA, 11Hospital Italiano de Buenos Aires, buenos aires, Argentina, 12Institut de Recherche Expérimentale et Clinique, Cliniques universitaires Saint-Luc, Université catholique de Louvain, St.-Lambrechts-Woluwe, Belgium, 13Instituto de Rehabilitación Psicofísica, Capital Federal, Argentina, 14Tel-Aviv Medical Center, Tel-Aviv, Israel, Petah-Tikva, Israel, 15Florida Medical Clinic, Tampa, FL, 16Uppsala University Hospital, Uppsala, Sweden, 17University of California, San Diego, San Diego, CA, 18Cliniques Universitaires Saint-Luc, Brussels, Belgium, 19Ospedale Sacro Cuore-Don Calabria, Verona, Italy, 20UF COM-J, Ponte Vedra Beach, FL, 21University of Ottawa - Ottawa, Ottawa, ON, Canada

    Background/Purpose: Enthesitis is a key domain in psoriatic arthritis (PsA). The Diagnostic Ultrasound Enthesitis Tool (DUET) study aims to develop a new PsA-specific sonographic scoring…
  • Abstract Number: 1724 • ACR Convergence 2024

    Performance of a Novel Cardiovascular Risk Calculator in Rheumatoid Arthritis

    Tate Johnson1, Halie Frideres2, Punyasha Roul3, Yangyuna Yang1, Joshua Baker4, Sauer brian5, grant Cannon6, Ted Mikuls1 and Bryant England1, 1University of Nebraska Medical Center, Omaha, NE, 2UNMC Department of Rheumatology, Omaha, NE, 3UNMC, Omaha, NE, 4University of Pennsylvania, Philadelphia, PA, 5Salt Lake City VA/University of Utah, Salt Lake City, UT, 6University of Utah and Salt Lake City VA, Salt Lake City, UT

    Background/Purpose: Existing cardiovascular disease (CVD) risk calculators have inadequately estimated CVD risk in people with rheumatoid arthritis (RA). The American Heart Association (AHA) recently developed…
  • Abstract Number: 2444 • ACR Convergence 2024

    Performance of the DETECT Algorithm and Cluster Analysis in Screening for Systemic Sclerosis Pulmonary Hypertension Groups

    Ryan Osgueritchian1, Hoda Mombeini1, Vivek Jani2, Adrianne Woods3, Steven Hsu1, Matthew Lammi4, Paul Hassoun4, Fredrick Wigley5, Laura Hummers6, Stephen Mathai7, Ami Shah8 and Monica Mukherjee1, 1Johns Hopkins University Division of Cardiology, Baltimore, MD, 2Johns Hopkins University School of Medicine, Baltimore, MD, 3Johns Hopkins University Division of Rheumatology, Baltimore, MD, 4Johns Hopkins University Division of Pulmonary and Critical Care Medicine, Baltimore, MD, 5Johns Hopkins University, Division of Rheumatology, Baltimore, MD, Baltimore, MD, 6Johns Hopkins University, Division of Rheumatology, Baltimore, MD, Ellicott City, MD, 7Johns Hopkins University Division of Pulmonary and Critical Care Medicine,, Blatimore, 8Division of Rheumatology, Johns Hopkins University, Ellicott City, MD

    Background/Purpose: Pulmonary hypertension (PH) portends poor outcomes in Systemic Sclerosis (SSc). Recent efforts for early identification and intervention in SSc patients with pulmonary arterial hypertension…
  • Abstract Number: 0293 • ACR Convergence 2024

    Assessment of Skin Cancer Risk in Autoimmune Diseases: A Multivariate Analysis Using a National Inpatient Database

    Sami Rabah and Xiangyi Kang, Lincoln Medical Center, New York, NY

    Background/Purpose: Autoimmune diseases are known to be associated with an increased risk of many types of cancers. This study investigates the association between different types…
  • Abstract Number: 0859 • ACR Convergence 2024

    Incidence of Aortic Aneurysm, Dissection, or Rupture Among Patients with Polymyalgia Rheumatica and Giant Cell Arteritis

    Kylie Carlson1, Mahmut Kaymakci2, Sebastian E. Sattui3 and Michael Putman4, 1Medical College of Wisconsin, Milwaukee, WI, 2Mayo Clinic, Rochester, MN, 3University of Pittsburgh, Pittsburgh, PA, 4The Medical College of Wisconsin, Milwaukee, WI

    Background/Purpose: Patients with polymyalgia rheumatica (PMR) may develop overt giant cell arteritis (GCA), but “subclinical” large vessel inflammation has also been reported in patients with…
  • Abstract Number: 1725 • ACR Convergence 2024

    Exploring Risks of Polymyalgia Rheumatica (PMR), Giant Cell Arteritis (GCA) and Complications While Receiving Immune Checkpoint Inhibitors: Comparative Analysis

    Irakli Tskhakaia and Arthur Lau, Jefferson Einstein Hospital, Philadelphia, PA

    Background/Purpose: Immune checkpoint inhibitors (ICIs) have transformed cancer treatment, offering significant benefits in various malignancies. However, these therapies can induce immune-related adverse events (irAEs), including…
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