ACR Meeting Abstracts

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Abstracts tagged "risk assessment"

  • Abstract Number: 1445 • ACR Convergence 2023

    SLESIS-R: An Improved Score for Prediction of Serious Infection in Patients with Systemic Lupus Erythematosus Based on the RELESSER Prospective Cohort

    Iñigo Rúa-Figueroa1, Maria Jesus Garcia de Yebenes2, JULIA MARTINEZ BARRIO3, Maria Galindo-Izquierdo4, Jaime Calvo- Alén5, Antonio Fernandez-Nebro6, Raúl Menor-Almagro7, Eva Tomero Muriel8, Mercedes Freire González9, Clara Sanguesa Gomez10, Loreto Horcada11, Ricardo Blanco12, Esther Uriarte Isacelaya13, Maria J. García-Villanueva14, Javier Narvaez15, Jose Rosas16, Silvia Gómez-Sabater17, Clara Moriano Morales18, Jose Luis Andreu-Sánchez19, Vicente Torrente-Segarra20, Elena Aurrecoechea Aguinaga21, Ana Pérez Gómez22, Javier Novoa Medina23, Eva Salgado-Pérez24, Nuria Lozano Rivas25, Carlos Montilla-Morales26, maria esther ruiz-lucea27, Marta Arévalo Salaet28, Carlota Iñíguez29, Lorena Expósito30, Mónica Ibáñez-Barceló31, Gema Bonilla32, Irene Carrión-Barberà33, Celia Erausquin34, Angela Pecondon-Español35, Francisco Javier Toyos Sáenz de Miera36, Tatiana Cobo37, Alejandro Muñoz38, Jorge Juan Fragio39, Jose Eloy Oller40, Beatriz Tejera Segura23 and Jose-Maria Pego-Reigosa41, 1Rheumatology, Hospital de Gran Canaria Doctor Negrin, Las Palmas de Gran Canaria, Spain, 2InMusc, Madrid, Spain, 3Rheumatology, Gregorio Marañon University Hospital, Madrid, Spain, 4Rheumatology, University Hospital of 12 de Octubre, Madrid, Spain, 5Rheumatology, Bioaraba Research Unit, Hospital Universitario Araba, Vitoria, Spain, 6Hospital Regional Universitario de Málaga, Malaga, Spain, 7Rheumatology, Hospital Jerez, Puerto De Santa María, Spain, 8Rheumatology, Hospital La Princesa, Madrid, Spain, 9Rheumatology department, Complexo Hospitalario Universitario A Coruña (CHUAC). Instituto de Investigación Biomédica A Coruña (INIBIC), A Coruña, Spain, 10Severo Ochoa Hospital, Madrid, Spain, 11Hospital de Navarra, Pamplona, Spain, 12Hospital Universitario Marqués de Valdecilla, IDIVAL, Santander, Spain, 13Rheumatology, University Hospital of Donosti, San Sebastián, Spain, 14Hospital Ramón y Cajal, Madrid, Spain, 15Hospital Universitario de Bellvitge, Barcelona, Spain, 16Hospital Marina Baixa, Alicante, Spain, 17Rheumatology Department, Dr. Balmis University General Hospital, Alicante. Institute for Health and Biomedical Research (ISABIAL), Alicante, Spain, 18Rheumatology, Hospital Universitario de León, León, Spain, 19Rheumatology, Hospital Universitario Puerta de Hierro, Majadahonda, Spain, 20Department of Rheumatology, Hospital de Sant Joan Despí Moises Broggi,, Sant Joan Despí, Spain, 21Department of Rheumatology, Hospital Sierrallana, Torrelavega, Spain, 22Rheumatology, Hospital Principe de Asturias, Alcalá de Henares, Spain, 23Complejo Hospitalario Universitario Insular de Gran Canaria, Las Palmas de Gran Canaria, Spain, 24Department of Rheumatology, University Hospital of Ourense, Ourense, Spain, 25Department of Rheumatology, Hospital Clínico Universitario Virgen de la Arrixaca, Murcia, Spain, 26Rheumatology, University Hospital of Salamanca, Salamanca, Spain, 27Hospita de Basurto, Bilbao, Spain, 28Rheumatology Department University Hospital Parc Taulí, Sabadell, Spain, 29Hospital Lucus Augusti, Lugo, Spain, 30Rheumatology Unit, Hospital Universitario de Canarias, San Cristóbal de La Laguna, Spain, 31Rheumatology, Hospital Universitari Son Llàtzer, Palma de Mallorca, Spain, 32Department of Rheumatology, Hospital Clínico Universitario La Paz, Madrid, Spain, 33Hospital del Mar, Barcelona, Spain, 34Rheumatology Department Hospital Universitario de Gran Canaria Doctor Negrín, Las Palmas de Gran Canaria, Spain, 35Hospital Miguel Servet, Zaragoza, Spain, 36Hospital Virgen Macarena, Sevilla, Spain, 37Department of Rheumatology, Hospital Universitario Infanta Sofía, Universidad Europea, Madrid, Spain, 38Hospital universitario Virgen del Rocío, El Viso de Alcor, Spain, 39Hospital General Universitario Valencia, Valencia, Spain, 40Hospital Doctor Peset, Valencia, Spain, 41Rheumatology, Hospital do Meixoeiro, Vigo, Spain

    Background/Purpose: Patients with systemic lupus erythematosus (SLE) have an increased risk of serious infections that varies with the severity of the disease, use of immunosuppressives,…
  • Abstract Number: 0292 • ACR Convergence 2023

    Comparison of Cardiovascular Risk of Myositis Patients and the General Population

    Sabina Oreska1, Hana Storkanova1, Jaroslav Kudlicka2, Vladimir Tuka2, Ondrej Mikes2, Zdislava Krupickova2, Martin Satny2, Eva Chytilova2, Jan Kvasnicka2, Maja Spiritovic3, Barbora Hermankova4, Petr Cesak5, Marian Rybar6, Karel Pavelka1, Ladislav Senolt7, Herman Mann8, Jiri Vencovsky1, Michal Vrablik2 and Michal Tomcik1, 1Institute of Rheumatology, Prague, Czech Republic, Department of Rheumatology, 1st Faculty of Medicine, Charles University, Prague, Czech Republic, 23rd Department of Internal Medicine, General University Hospital and 1st Faculty of Medicine, Charles University, Prague, Czech Republic, 3Institute of Rheumatology, Prague, Czech Republic, Department of Physiotherapy, Faculty of Physical Education and Sport, Charles University, Prague, Czech Republic, 4Department of Physiotherapy, Faculty of Physical Education and Sport, Charles University, Prague, Czech Republic, 5Department of Human Movement Laboratory, Faculty of Physical Education and Sport, Charles University, Prague, Czech Republic, 6Department of Biomedical Technology, Faculty of Biomedical Engineering, Czech Technical University in Prague, Kladno, Czech Republic, 7Institute of Rheumatology and Department of Rheumatology, First Faculty of Medicine, Praha, Czech Republic, 8Institute of Rheumatology, Praha 2, Czech Republic

    Background/Purpose: Cardiovascular (CV) risk due to accelerated atherosclerosis and impaired metabolism can be increased in idiopathic inflammatory myopathies (IIM) on behalf of systemic inflammation, limited…
  • Abstract Number: 1486 • ACR Convergence 2023

    Clinical Outcomes in Patients Admitted for ST-Elevation Myocardial Infarction with vs Without Systemic Lupus Erythematosus: An Analysis from National Inpatient Sample Database (2015-2018)

    Hamza Liaqat1, Muhammad Qureshi2, Awais Farooq3, Mashal Awais2, Amar Patel4 and Aisha Barlas5, 1Wah Medical College, Wah Cantt, Pakistan, 2Southeast Health Internal Medicine Residency Prog., Dothan, AL, 3University of Illinois Chicago, Chicago, IL, 4Texas Tech University Health Sciences Center, El paso, TX, 5Mercy Health, Rockford, IL

    Background/Purpose: Impact of systemic lupus erythematosus (SLE) on the clinical outcomes of patients admitted for ST-elevation myocardial infarction (STEMI).Methods: Patient data was collected for years…
  • Abstract Number: 0387 • ACR Convergence 2023

    The Association Between Inflammation, High-Sensitivity Cardiac Troponin T, and Cardiovascular Events in Rheumatoid Arthritis

    Brittany Weber1, Dana Weisenfeld1, Mary Jeffway1, Jonathan Coblyn1, Michael Weinblatt2, Nancy Shadick3, Marcelo DiCarli1 and Katherine Liao1, 1Brigham and Women's Hospital, Boston, MA, 2Harvard Medical School, Waban, MA, 3Brigham and Women's Hospital, Boston, MA

    Background/Purpose: Patients with rheumatoid arthritis (RA) have a 1.5x excess risk of cardiovascular (CV) disease compared to the general population, attributed to chronic inflammation. In…
  • Abstract Number: 1604 • ACR Convergence 2023

    First and Recurrent Thrombosis Risk After 4,454 Patient-Years of Follow-Up: Prospective Results from the AntiPhospholipid Syndrome Alliance for Clinical Trials and InternatiOnal Networking (APS ACTION) Clinical Database and Repository (“Registry”)

    Jonathan Thaler1, Yasaman Ahmadzadeh2, Danieli Andrade3, leslie skeith4, Maria Tektonidou5, Savino Sciascia6, Vittorio Pengo7, Jose Pardos-Gea8, Guillermo Ruiz-Irastorza9, Chary Lopez-Pedrera10, H Michael Belmont11, Kello Nina12, Paul R. Fortin13, Denis WAHL14, Maria Gerosa15, Guilherme De Jesús16, Zhuoli Zhang17, Tatsuya Atsuma18, Maria Efthymiou19, D. Ware Branch20, Laura Andreoli21, Esther Rodriguez almaraz22, Michelle Petri23, Giulia Pazzola24, Ricard Cervera25, Bahar Artim Esen26, Hui Shi27, Jason Knight27, Guillermo Pons-Estel28, Rohan Willis29, Ali Duarte-Garcia30, Maria Laura Bertolaccini31, Hannah Cohen32, Doruk Erkan1 and On Behalf Of APS ACTION33, 1Hospital for Special Surgery, New York, NY, 2Roger Williams Medical Center, Providence, RI, 3University of São Paulo, São Paulo, Brazil, 4University of Calgary, Calgary, AB, Canada, 5Joint Academic Rheumatology Program, First Department of Propedeutic and Internal Medicine, National and Kapodistrian University of Athens, Athens, Greece, 6University of Turin, Torino, Italy, 7Department of Cardiac-Thoracic-Vascular Sciences and Public Health University of Padova, Padova, Italy, 8Vall d'Hebron University Hospital, Barcelona, Spain, 9Hospital Universitario Cruces, Barakaldo, Spain, 10IMIBIC - Reina Sofia Hospital, Córdoba, Spain, 11NYU School of Medicine, New York, NY, 12Northwell Health, Brooklyn, NY, 13Centre ARThrite - CHU de Québec - Université Laval, Quebec City, QC, Canada, 14University of Lorraine, Nancy, France, 15University of Milan, Milano, Italy, 16Universidade do Estado do Rio de Janeiro, Rio De Janeiro, Brazil, 17Peking University First Hospital, Rheumatology and Immunology Department, Beijing, China, 18Hokkaido University, Department of Rheumatology, Endocrinology and Nephrology, Sapporo, Japan, 19University College London, London, United Kingdom, 20University of Utah, Salt Lake City, UT, 21University of Brescia, Brescia, Italy, 22Hospital Universitario 12 de Octubre, Madrid, Spain, 23Department of Medicine, Division of Rheumatology, Johns Hopkins University School of Medicine, Timonium, MD, 24Azienda Ospedaliera Santa Maria Nuova di Reggio Emilia, Reggio Emilia, Italy, 25Hospital Clínic de Barcelona, Barcelona, Spain, 26Istanbul University, Istanbul Faculty of Medicine, Department of Internal Medicine, Division of Rheumatology, Istanbul, Turkey, 27University of Michigan, Ann Arbor, MI, 28CREAR, Rosario, Argentina, 29University of Texas Medical Branch, Galveston, TX, 30Mayo Clinic, Rochester, MN, 31King's College London, London, United Kingdom, 32University College London Hospitals NHS Foundation Trust, London, United Kingdom, 33on behalf of APS ACTION, New York, NY

    Background/Purpose: The APS ACTION Registry was created to study the natural course of disease over 10 years in persistently antiphospholipid antibody (aPL)-positive patients with or…
  • Abstract Number: 0388 • ACR Convergence 2023

    Left Ventricular Geometry Abnormalities Are Related to Higher Clinical Activity in Rheumatoid Arthritis Patients

    Victor Beltran1, Iris Colunga2, Dionicio A. Galarza-Delgado2, José Ramón Azpiri-López2, Jesus Alberto Cardenas-De la Garza3, Rosa Arvizu-Rivera4, Valeria Gonzalez-Gonzalez5 and Angel Arias Peralta6, 1Rheumatology Service Hospital Universitario "Dr. José Eleuterio González", Monterrey, Mexico, 2Hospital Universitario UANL, Monterrey, Mexico, 3Hospital Universitario "Dr. José Eleuterio González", San Nicolas, Mexico, 4Hospital Universitario "Dr. José Eleuterio Gonzalez", Escobedo, Mexico, 5Universidad Autónoma de Nuevo León, Monterrey, Mexico, 6Medicine Faculty, Universidad Autonoma De Nuevo Leon, Monterrey, Mexico

    Background/Purpose: Rheumatoid arthritis (RA) leading cause of death is cardiovascular (CV) disease. RA patients can develop silent myocardial tissue alterations, which result in changes in…
  • Abstract Number: 1682 • ACR Convergence 2023

    Prospective Evaluation of Anti-SSA/Ro Pregnancies Supports the Utility of High Titer Antibodies and Fetal Home Monitoring for the Detection of Fetal Atrioventricular Block

    Bettina Cuneo1, Mala Masson2, Colin Phoon3, Ashley Roman3, Peter Izmirly4, Amit Saxena5, Michael Belmont6, Christina Penfield3, Young Mi Lee3, Julie Nusbaum7, Ruben Acherman8, Elena Sinkovskaya9, Alfred Abuhamad10, Majd Makhoul11, Gary Satou12, Whitnee Hogan13, Nelangi Pinto13, Anita Moon-Grady14, Lisa Howley15, Mary Donofrio16, Anita Krishnan16, Homa Ahmadzia17, Stephanie Levasseur18, Erin Paul19, Sonal Owens20, Kristopher Cumberback21, Jyothi Matta22, Gary Joffe23, Christopher Lindblade24, Andrew Rubenstein25, Caitlin Haxel26, Katherine Kohari27, Joshua Copel27, James Strainic28, Tam Doan29, Karla Bermudez-Wagner29, Shreya Sheth29, Stacy Killen30, Theresa Tacy31, Michelle Kaplinski31, Lisa Hornberger32, Nicola Fraser3, Robert Clancy3 and Jill Buyon33, 1University of Colorado, Denver, Denver, CO, 2New York University, New York, NY, 3NYU Grossman School of Medicine, New York, NY, 4New York University School of Medicine, New York, NY, 5NYU Langone, New York, NY, 6New York University Langone Medical Center, New York, NY, 7NYU Long Island School of Medicine, Mineola, NY, 8Children's Heart Center, Las Vegas, NV, 9East Virginia Medical School, East Virginia Medical School, VA, 10East Virginia Medical School, Norfolk, VA, 11Atrium Health Levine Children's Hospital, Charlotte, NC, 12University of California Los Angeles, Los Angeles, CA, 13University of Utah, Salt Lake City, UT, 14University of California San Francisco, San Francisco, CA, 15Midwest Fetal Care Center, Children's Minnesota/Allina Health, Minneapolis, MN, 16Children's National Hospital, Washington, DC, 17George Washington University, Washington, DC, 18Columbia University, New York, NY, 19Mount Sinai, New York, NY, 20University of Michigan, Ann Arbor, MI, 21University of Kentucky, Lexington, KY, 22University of Louisville, Louisville, KY, 23Perinatal Associates of New Mexico, Albuquerque, NM, 24Phoenix Children's Hospital, Phoenix, AZ, 25Dignity Health, Phoenix, AZ, 26University of Vermont Children's Hospital, Burlington, VT, 27Yale University, New Haven, CT, 28UH Rainbow Babies, Cleveland, OH, 29Baylor School of Medicine, Houston, TX, 30Vanderbilt University, Nashville, TN, 31Stanford University, Stanford, CA, 32Stollery Children's Hospital, Edmonton, AB, Canada, 33Department of Medicine, NYU Grossman School of Medicine, New York, NY

    Background/Purpose: The management of fetuses exposed to maternal anti-SSA/Ro autoantibodies is challenging as the clinician weighs the rarity of fetal atrioventricular block (AVB) against the…
  • Abstract Number: 0446 • ACR Convergence 2023

    Review of Rheumatoid Arthritis Treatment Landscape During the COVID-19 Pandemic

    Rachel Connolly1, MamTing Thoo2, Elizabeth Baynton3 and Denise Baldock3, 1Ipsos, New York, NY, 2Ipsos SDN BHD, Kuala Lumpur, Malaysia, 3Ipsos MORI UK, London, United Kingdom

    Background/Purpose: During the COVID-19 pandemic, guidelines were amended with respect to the prescribing of biologic/tsDMARD usage to treat rheumatoid arthritis (RA). In addition, regulatory reviews…
  • Abstract Number: 1768 • ACR Convergence 2023

    The Dynamics of the Gut Microbiome in Rheumatoid Arthritis Susceptibility: A Cross-Sectional and Longitudinal Observational Study

    Christopher Rooney1, Ian Jeffery2, Kulveer Mankia3, Mark Wilcox1 and Paul Emery4, 1University of Leeds, Leeds, United Kingdom, 24D Pharma plc, Cork, Ireland, 3Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, Leeds, United Kingdom, 4Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, and NIHR Leeds Biomedical Research Centre, Leeds Teaching Hospitals NHS Trust, Leeds, United Kingdom

    Background/Purpose: Multiple compositional shifts of gut microbiota have been identified within the rheumatoid arthritis (RA) disease continuum, encompassing both established RA and at-risk individuals (including…
  • Abstract Number: 0571 • ACR Convergence 2023

    A Polygenic Risk Score for Systemic Lupus Erythematosus (SLE) Discriminates Between Patients with Lupus and Individuals Without Lupus and a Positive Antinuclear Antibody Test

    Gul Karakoc1, Ge Liu1, Jacy Zanussi2, Cecilia Chung2, Jorge Gamboa1, Jonathan Mosley1, Nancy Cox1, C. Michael Stein1 and Vivian Kawai1, 1Vanderbilt University Medical Center, Nashville, TN, 2University of Miami, Miami, FL

    Background/Purpose: A positive ANA (ANA-POS) test is present in almost all patients with SLE and is also frequently present in other autoimmune (AI) diseases and…
  • Abstract Number: 1950 • ACR Convergence 2023

    Thromboembolic Risk Associated with Intravenous Immune Globulin Use in Patients with Idiopathic Inflammatory Myopathy: A Large Database Study

    Rohan Mehta1, Mike Putman2 and Didem Saygin3, 1Medical College of Wisconsin, Milwaukee, WI, 2Division of Rheumatology, Medical College of Wisconsin, Milwaukee, WI, 3University of Pittsburgh, Pittsburgh, PA

    Background/Purpose: Intravenous immune globulin (IVIG) recently received regulatory approval for the treatment of dermatomyositis, one of the idiopathic inflammatory myopathies (IIM). The pivotal randomized trial…
  • Abstract Number: 0620 • ACR Convergence 2023

    Physical and Mental Health in Early Systemic Sclerosis: Baseline Results for Patient-Reported Outcomes Measurement Information System-29 from the Collaborative National Quality and Efficacy Registry

    Isha Lamba1, Ashima Makol2, Dinesh Khanna3, John VanBuren4, Angela Child4, Jessica Alvey4, Shervin Assassi5, Elana Bernstein6, Flavia Castelino7, Lorinda Chung8, Luke Evnin9, Tracy Frech10, Faye Hant11, Laura Hummers12, Kimberly Lakin13, Dorota Lebiedz-Odrobina14, Yiming Luo15, Jerry Molitor16, Duncan Moore17, Carrie Richardson18, Nora Sandorfi19, Ami Shah20, Ankoor Shah21, Victoria Shanmugam22, Brian Skaug23, Virginia Steen24, Elizabeth Volkmann25 and Jessica Gordon13, 1New York Presbyterian Hospital/Weill Cornell Medical Centre, New York, NY, 2Mayo Clinic, Rochester, MN, Rochester, MN, 3University of Michigan, Ann Arbor, MI, 4University of Utah, Salt Lake City, UT, 5University of Texas McGovern Medical School at Houston, Houston, TX, 6Columbia University, New York, NY, 7Massachusetts General Hospital, Boston, MA, 8Department of Medicine, Division of Immunology and Rheumatology, Stanford University School of Medicine, Woodside, CA, 9Scleroderma Research Foundation, Brisbane, CA, 10Vanderbilt University Medical Center, Nashville, TN, 11Medical University of South Carolina, Charleston, SC, 12Johns Hopkins University, Baltimore, MD, 13Hospital for Special Surgery, New York, NY, 14University of Utah, Cottonwood Heights, UT, 15Division of Rheumatology, Department of Medicine, Columbia University Irving Medical Center, New York, NY, 16University of Minnesota, Minneapolis, MN, 17Northwestern Memorial Hospital, Chicago, IL, 18Northwestern University, Riverside, IL, 19University of Pennsylvania, Philadelphia, PA, 20Department of Medicine, Division of Rheumatology, Johns Hopkins University School of Medicine, Ellicott City, MD, 21Duke University, Durham, NC, 22Victoria Shanmugam, MD, Great Falls, VA, 23Division of Rheumatology, University of Texas McGovern Medical School, Houston, TX, 24Georgetown University School of Medicine, Washington, DC, 25University of California Los Angeles, Los Angeles, CA

    Background/Purpose: Patient-Reported Outcomes Measurement Information System-29 version 2.0 (PROMIS-29v2) is a patient-centered questionnaire used to assess health-related quality of life (HRQoL). PROMIS-29v2 has shown validity…
  • Abstract Number: 1996 • ACR Convergence 2023

    Variation in Dual-energy X-ray Absorptiometry Reporting: A National Survey of Veterans Health Administration Clinics

    Karla Miller1, Melissa Steffen2, Kimberly McCoy2, Michelle Mengeling2, Heather Davila2, Shylo Wardyn2 and Samantha Solimeo2, 1University of Utah School of Medicine, Salt Lake City, UT, 2Department of Veterans Affairs, Iowa City VA HCS, Iowa City, IA

    Background/Purpose: Dual-energy x-ray absorptiometry (DXA) is an important tool to identify Veterans with osteoporosis, assess fracture risk, and monitor treatment response. Variability in DXA acquisition,…
  • Abstract Number: 0633 • ACR Convergence 2023

    Prediction of Progressive Fibrosing Interstitial Lung Disease in Systemic Sclerosis Patients: Insight from the CRDC Cohort Study

    Min Hui1, Xinwang Duan2, Jiaxin Zhou3, Mengtao Li3, Qian Wang4, Jiuliang Zhao1, Yong Hou1, Dong Xu5 and xiaofeng Zeng4, 1Department of Rheumatology, Peking Union Medical College Hospital, Beijing, China, 2Department of Rheumatology, The Second Affiliated Hospital of Nanchang University, Beijing, China, 3Peking Union Medical College Hospital, Beijing, China, 4Department of Rheumatology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China, 5Department of Rheumatology, Peking Union Medical College, Beijing, China

    Background/Purpose: Systemic sclerosis (SSc) patients can develop progressive fibrosing interstitial lung disease (PF-ILD), linked to a poor outcome. This study aims to establish a reliable…
  • Abstract Number: 2132 • ACR Convergence 2023

    Systematic Screening for Multimorbidities Leads to an Increased Use of Comorbidity-preventing Medications and Lower Hospitalization Rates

    Claire Daien1, Vera Georgescu2, Guillaume Decarriere3, Gael Mouterde3, Cedric Lukas4, Gregoire Mercier2 and JACQUES MOREL5, 1University Hospital, Montpellier, France, 2Department of Medical Information, Montpellier, France, 3Rheumatology, Montpellier, France, 4CHU Montpellier, Montpellier, France, 5Protocole thérapeutique immuno-rhumatologie, Montpellier, France

    Background/Purpose: Systematic screening for multimorbidities has been carried out since 2014 at Montpellier University Hospital in patients with chronic inflammatory rheumatism (IRD). The aim of…
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