ACR Meeting Abstracts

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Abstracts tagged "risk assessment"

  • Abstract Number: 2245 • ACR Convergence 2025

    Add-on of Coronary Artery Calcium Score Significantly Improves the Risk Prediction of Cardiovascular Diseases in Patients with Rheumatoid Arthritis: From a Real-world Cohort Study

    Yao-Wei Zou, Ying Yang, Zhi-Ming Ouyang, Ran Shi, Tao Wu, Kui-Min Yang, Jian-Da Ma and Lie Dai, Department of Rheumatology and Immunology, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou, China (People's Republic)

    Background/Purpose: Cardiovascular diseases (CVD) are the first cause of death in patients with rheumatoid arthritis (RA). The guidelines recommend risk prediction in all RA patients.…
  • Abstract Number: 1468 • ACR Convergence 2025

    A HIPAA-Compliant LLM for Personalized Therapeutic Decision-Making in Lupus Nephritis

    Abhimanyu Amarnani1, Zaynab Marzuk2 and H Michael Belmont3, 1New York University Grossman School of Medicine, New York, NY, 2NYU Langone / FHC, brooklyn, NY, 3NYU School of Medicine, New York, NY

    Background/Purpose: Lupus nephritis (LN) is the most significant driver of morbidity and mortality in patients with systemic lupus erythematosus (SLE). The ACR 2024 lupus nephritis…
  • Abstract Number: 0490 • ACR Convergence 2025

    Infection Risks Associated with Monotherapy and Combination Therapies Using Biological or Targeted – DMARD in RA: A Systematic Review and Network Meta-analysis

    Li Liu1, Xue-Mei Zhang1, Zhi-Chun Gu1 and Jia Li2, 1Ren Ji Hospital, Shanghai Jiao Tong University School Of Medicine, Pu Dong Xin Qu, Shanghai, China (People's Republic), 2Department of Rheumatology, Renji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China (People's Republic)

    Background/Purpose: This study aimed to evaluate the infection risks in patients with rheumatoid arthritis (RA) treated with biological or targeted synthetic disease-modifying antirheumatic drugs (b/tsDMARDs),…
  • Abstract Number: 2200 • ACR Convergence 2025

    Obstetric and Neonatal Complications in Women living with Axial Spondyloarthritis: a population-based, matched cohort study

    Sinead Maguire1, John Snelgrove2, Priscila Pequeno3, Michael Paterson4, Fangyun Wu4, Laura Passalent5, Anthony Perruccio6, Dharini Mahendira7, Elie Karam8, Robert Inman9 and Nigil Haroon10, 1Our Lady's Hospital Navan, Dublin, Dublin, Ireland, 2Mount Sinai Hospital, Toronto, Canada, 3Institute for Clinical Evaluative Sciences (ICES), Toronto, Canada, 4Institute of Clinical & Evaluative Sciences, Toronto, Canada, 5Schroeder Arthritis Institute, University Health Network, Toronto, ON, Canada, 6Schroeder Arthritis Institute and Krembil Research Institute, University Health Network, Toronto, Canada, 7St Michael's Hospital, Toronto, Canada, 8Canadian Spondylitis Association, Toronto, Canada, 9University Health Network, Toronto, ON, Canada, 10Department of Medicine/Rheumatology, University Health Network, Schroeder Arthritis Institute, University of Toronto, Toronto, ON, Canada

    Background/Purpose: Women with axial spondyloarthritis (axSpA) are frequently diagnosed during their childbearing years. While studies have reported on pregnancy complications in this population, deriving generalizable…
  • Abstract Number: 1391 • ACR Convergence 2025

    Assessment of Anti-SSA/Ro Testing Across Various Commercial Laboratories in the United States to Reduce the Burden of Surveillance in Pregnant Women with No History of Fetal Atrioventricular Block (fAVB)

    Mala Masson1, Bettina Cuneo2, Philip Carlucci3, Peter Izmirly4, Justin Brandt5, Colin Phoon6, Ashley Roman6, Amit Saxena7, Michael Belmont5, Christina Penfield6, Young Mi Lee6, Julie Nusbaum5, Andrew Rubenstein6, Elena Sinkovskaya8, Alfred Abuhamad8, Gary Satou9, Whitnee Hogan10, Anita Moon-Grady11, Lisa Howley12, Mary Donofrio13, Stephanie Levasseur14, Miwa Geiger15, Sonal Owens16, Kristopher Cumbermack17, Jyothi Matta18, Gary Joffe19, Christopher Lindblade20, Caitlin Haxel21, Katherine Kohari22, Joshua Copel22, James Strainic23, Tam Doan24, Conisha Holloman24, Stacy Killen25, Theresa Tacy26, Michelle Kaplinski26, Nalani Sachan6, Nicola Fraser6, Robert Clancy14 and Jill Buyon6, 1NYU Langone Medical Center- Division of Rheumatology, New York, NY, 2University of Arizona College of Medicine, Tucson, AZ, 3New York University School of Medicine, New York, NY, 4New York University Grossman School of Medicine, New York, NY, 5NYU Langone Health, New York, NY, 6NYU Grossman School of Medicine, New York, NY, 7Division of Rheumatology, Department of Medicine, NYU Grossman School of Medicine, New York, NY, 8Eastern Virginia Medical School, Norfolk, VA, 9University of California Los Angeles, Los Angeles, CA, 10University of Utah, Salt Lake City, UT, 11University of California San Francisco, San Francisco, CA, 12Midwest Fetal Care Center, Children's Minnesota/Allina Health, Minneapolis, MN, 13Children's National Hospital, Washington, DC, 14Columbia University, New York, NY, 15Mount Sinai School of Medicine, New York, NY, 16University of Michigan, Ann Arbo, MI, 17University of Kentucky, Lexington, KY, 18University of Louisville, Louisville, KY, 19Perinatal Associates of New Mexico, Albuquerque, NM, 20Phoenix Children's Hospital, Phoenix, AZ, 21University of Vermont Children's Hospital, Burlington, VT, 22Yale University, New Haven, CT, 23UH Rainbow Babies, Cleveland, OH, 24Baylor College of Medicine, Houston, TX, 25Vanderbilt University, Nashville, TN, 26Stanford University, Stanford, CA

    Background/Purpose: For women with Sjögren's disease, the risk of Fetal Atrioventricular Block (fAVB) is a critical aspect in pregnancy counseling. To date, the most reliable…
  • Abstract Number: 0458 • ACR Convergence 2025

    TyG-BMI Index as a Serological Biomarker for Carotid Plaque and Cardiac Function Changes in Rheumatoid Arthritis

    Rebeca L. Polina-Lugo1, Oscar Azael Garza-Flores2, Fernanda M. Garcia-Garcia3, Esteban C. Garza-Gonzalez4, Jesus Alberto Cardenas-de la Garza5, Iris J. Colunga-Pedraza3, Jose R Azpiri-Lopez6, Dionicio A. Galarza-Delgado3, Victor M Fraga-Enriquez7 and Diego Azamat Salcedo Almanza8, 1Division of Rheumatology, University Hospital "Dr. Jose Eleuterio Gonzalez", Universidad Autonoma de Nuevo Leon, Monterrey, Nuevo León, Mexico, 2Rheumatology Service, Hospital Universitario Dr. José Eleuterio González, Universidad Autónoma de Nuevo León, Guadalupe, Mexico, 3Rheumatology Service, Hospital Universitario Dr. José Eleuterio González, Universidad Autónoma de Nuevo León, Monterrey, Mexico, 4Rheumatology Service, Hospital Universitario Dr. José Eleuterio González, Universidad Autónoma de Nuevo León, San Nicolas de los Garza, Nuevo Leon, Mexico, 5Rheumatology Service, University Hospital “Dr. José Eleuterio González”, Universidad Autónoma de Nuevo León, Monterrey, México, Monterrey, Mexico, 6Cardiology Service, Hospital Universitario Dr. José Eleuterio González, Universidad Autónoma de Nuevo León, Monterrey, Mexico, 7Cardiology Service, Hospital Universitario “Dr. Jose Eleuterio Gonzalez”, Universidad Autonoma de Nuevo Leon, Monterrey, Nuevo Leon, Mexico, 8Radiology Service, Hospital Universitario “Dr. Jose Eleuterio Gonzalez”, Universidad Autonoma de Nuevo Leon, Monterrey, Nuevo Leon, Mexico

    Background/Purpose: The Triglyceride-Glucose-BMI index (TyG-BMI) is a reliable method for detecting insulin resistance (IR), with effectiveness comparable to the gold standard. Elevated TyG-BMI levels have…
  • Abstract Number: 2072 • ACR Convergence 2025

    Results of an Integrated Program for Early Cancer Detection in Idiopathic Inflammatory Myopathies

    valeria cantu1, Rebeca L. Polina-Lugo1, Emmanuel Dominguez-Chapa2, Ana Cecilia Bardan Inchaustegui3, Rosa Arvizu-Rivera4, fernanda m. garcia-Carrillo5, Ericka S. Reyna-Hernandez6, Daniela A. Mejia-Rodriguez6, Jesus Alberto Cardenas-de la Garza7 and Miguel Villarreal-Alarcón8, 1Division of Rheumatology, University Hospital "Dr. Jose Eleuterio Gonzalez", Universidad Autonoma de Nuevo Leon, Monterrey, Nuevo León, Mexico, 2Universidad Autonoma de Nuevo Leon, Monterrey, Nuevo León, Mexico, 3Universidad Autónoma de Nuevo Leon, Monterrey, Nuevo León, Mexico, 4Hospital Universitario "Dr. José Eleuterio Gonzalez", Escobedo, Nuevo León, Mexico, 5Hospital Universitario "Dr. José Eleuterio González" UANL, Monterrey, Nuevo Leon, Mexico, 6Rheumatology Service, Hospital Universitario “Dr. Jose Eleuterio Gonzalez”, Universidad Autonoma de Nuevo Leon, Monterrey, Nuevo Leon, Mexico, 7Rheumatology Service, University Hospital “Dr. José Eleuterio González”, Universidad Autónoma de Nuevo León, Monterrey, México, Monterrey, Mexico, 8Hospital Universitario UANL, Monterrey, Nuevo León, Mexico

    Background/Purpose: Cancer risk is significantly increased in Idiopathic Inflammatory Myopathies (IIM), particularly within the first 3 to 5 years after diagnosis. Given that cancer represents…
  • Abstract Number: 1386 • ACR Convergence 2025

    Characterization and Progression of Localized Amyloidosis in Sjogren’s Syndrome: Evidence Long-Term (1995-2025) Follow-Up of a Cohort compared to Literature Review.

    Hoang Nguyen1, Philip Moresco2, Antoine Chiu2, Asha Patnaik3 and Peter Gorevic4, 1Stony Brook University-Renaissance School of Medicine- Department of Rheumatology, Jamaica, NY, 2Stony Brook University -Renaissance School of Medicine, Stony Brook, NY, 3Stony Brook University Hospital, Stony Brook, NY, 4Stony Brook University, Stony Brook, NY

    Background/Purpose: -Sjogren’s syndrome (SS) is a chronic autoimmune disorder, defined by keratoconjunctivitis sicca (KCS), specific serologies, and a significant risk of extra-exocrine disease manifestations and…
  • Abstract Number: 0437 • ACR Convergence 2025

    Lipid Screening in Rheumatoid Arthritis: A Retrospective Cohort Study Highlighting Gaps in Cardiovascular Risk Prevention

    Anokhi Saklecha1, Amelia Khoo2, Sierra Mendelsohn2, Abhijeet Danve3, Mei Xue Dong4 and Lisa Suter2, 1Yale University, New Haven, CT, 2Yale School of Medicine, New Haven, CT, 3Section of Rheumatology, Department of Medicine, Yale School of Medicine, New Haven, CT, 4Yale-New Haven Medical Center, new haven, CT

    Background/Purpose: Rheumatoid arthritis (RA) is associated with a 1.5 to 2 fold increased risk of cardiovascular disease (CVD) due to systemic inflammation and endothelial dysfunction.…
  • Abstract Number: 2009 • ACR Convergence 2025

    Value of New PREVENT Calculator in Detecting Cardiovascular Disease in Patients with Gout

    Patrick Williamson1, Rouhin Sen2 and Angelo Gaffo3, 1Tinsley Harrison Internal Medicine Residency, Department of Medicine, University of Alabama at Birmingham, Birmingham, 2University of Alabama at Birmingham, Department of Medicine, Division of Clinical Immunology & Rheumatology, Birmingham, 3Division of Rheumatology and Clinical Immunology, University of Alabama, Birmingham, AL, USA; Birmingham VA Medical Center, Birmingham, AL, USA, Birmingham, AL

    Background/Purpose: Gout is associated with a 50% increased risk of cardiovascular disease (CVD).1 The current recommendation for evaluating CVD risk in gout is to use…
  • Abstract Number: 1166 • ACR Convergence 2025

    Biomarkers Associated with Left Atrial Structure and Function in Individuals with Psoriasis

    Julie Borchsenius1, Maria Dons2, Morten Sengeløv3, Flemming Olsen4, Caroline Espersen4, Kristoffer Skaarup3, Mats Lassen4, Niklas Johansen4, Filip Davidovski3, Manan Pareek4, Brittany Weber5, Claus Zachariae6, Lone Skov6 and Tor Biering-Sørensen3, 1CTCPR / Center for translational cardiology and pragmatic research trials, Charlottenlund, Denmark, 2Copenhagen University Hospital Gentofte, Copenhagen, Hovedstaden, Denmark, 3Center for Translational Cardiology and Pragmatic Randomized Trials, Dep. of Cardiology, Copenhagen University Hospital - Gentofte, Copenhagen, Hovedstaden, Denmark, 4CTCPR / Center for translational cardiology and pragmatic research trials, Copenhagen, Denmark, 5Brigham and Women's Hospital, DEDHAM, MA, 6Dep. of Dermatology and Allergy, Copenhagen University Hospital – Herlev & Gentofte, Copenhagen, Hovedstaden, Denmark

    Background/Purpose: Individuals with psoriasis are at increased risk of developing heart disease. Echocardiographic parameters of impaired left atrial (LA) strain (Peak atrial contraction and longitudinal…
  • Abstract Number: 0436 • ACR Convergence 2025

    Why Do Patients with Rheumatic Disease Have MACE and Thrombotic Events?

    Andrea Mazariego and Maria Greenwald, Desert Medical Advances, Rancho Mirage, CA

    Background/Purpose: Patients with rheumatic disease have an increased risk for thrombotic events and major adverse cardiac events (MACE) due to systemic inflammation. Bleeding time is…
  • Abstract Number: 2007 • ACR Convergence 2025

    Machine Learning-Based Prediction of Gout Onset in Individuals with Asymptomatic Hyperuricemia Using a Common Data Model

    Min Jung Kim1, Sang Min Lee2, Jun Seok Kim2, Borim Ryu2 and Kichul Shin3, 1Seoul Metropolitan Government Boramae Medical center, Dongjak-gu, Seoul, South Korea, 2Center for Data Science, Biomedical Research Institute, Seoul Metropolitan Government–Seoul National University Hospital Boramae Medical Center, Seoul, Republic of Korea, 3Seoul National University, Seoul, South Korea

    Background/Purpose: Long-term hyperuricemia is essential for the development of gout. However, only 9.9% of individuals with asymptomatic hyperuricemia (AHU) develop gout within 10 years. Identifying…
  • Abstract Number: 1122 • ACR Convergence 2025

    A Retrospective Study of Adverse Cardiovascular Events in Patients Started on JAK Inhibitors at Two Major Health Systems in Northeast Ohio: Analysis of the 2019 JAK Inhibitors FDA Boxed Warning for Increased Risk of Serious Heart-Related Problems

    William Koch1, Donald Anthony2, Janeen Leon2 and Nora G. Singer2, 1University Hospitals Parma Medical Center, Parma, OH, 2The MetroHealth System at Case Western Reserve University School of Medicine, Cleveland, OH

    Background/Purpose: Janus kinase (JAK) inhibitors are immunosuppressive medications that target the JAK-STAT signaling pathway. Tofacitinib (Xeljanz) was the first JAK inhibitor approved for the treatment…
  • Abstract Number: 0342 • ACR Convergence 2025

    Comparison of Cortical Backscatter Ultrasound, Reference-Point Indentation and Bone Mineral Density in Discriminating Prevalent Fragility Fractures in Inflammatory Rheumatic Diseases: A Pilot Study

    Edgar Wiebe1, Benjamin Kuntz2, Angela Galindo Santos3, Zhivana Boyadzhieva3, Sandra Hermann1, Burkhard Muche2, Andriko Palmowski2, Gerhard Krönke4, Ralf Schmidmaier5, Kay Raum3 and FRANK BUTTGEREIT6, 1Department of Rheumatology and Clinical Immunology, Charité - Universitätsmedizin Berlin, Berlin, Germany, Berlin, Berlin, Germany, 2Charité – Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany, 3Charité – Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Berlin, Germany, 4Department of Rheumatology and Clinical Immunology, Charité - Universitätsmedizin Berlin, Berlin, Germany; Deutsches Rheuma-Forschungszentrum Berlin, Berlin, Germany, Berlin, Berlin, Germany, 5Klinikum der Universität München, Medizinische Klinik und Poliklinik IV, München, Bayern, Germany, 6Charité University Medicine Berlin, Berlin, Berlin, Germany

    Background/Purpose: Patients with inflammatory rheumatic and musculoskeletal diseases (iRMDs) are at elevated risk for osteoporotic fragility fractures. Standard assessment via dual-energy X-ray absorptiometry (DXA) does…
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