Abstracts tagged "Rheumatoid Factor and rheumatoid arthritis (RA)"

Abstract Number: 1489 • 2018 ACR/ARHP Annual Meeting
“Continuous Reduction” in Serum RF Titers Predicts Low Disease Activity and Good Therapeutic Response in RA Patients Treated with TNF Inhibitors, but Does Not Relate to Clinical Outcomes during ABT Treatment
Takayoshi Owada¹, Kazuhiro Kurasawa¹, Yuta Takamura¹, Tomoyuki Miyao¹, Ayae Tanaka¹, Ryutaro Yamazaki², Satoko Arai¹, Reika Maezawa¹ and Masafumi Arima³, ¹Rheumatology, Dokkyo Medical University, Mibu, Tochigi, Japan, ²Rheumatology, Dokkyo Medical University, Mibu, tochigi, Japan, ³Rheumatology, Dokkyo Medical University, mibu-gun, Tochigi, Japan
Background/Purpose: Relative change of serum RF titer has been reported to correlate with those of RA disease activity. However, it is debatable whether serum RF…
Abstract Number: 410 • 2017 ACR/ARHP Annual Meeting
Association between Anti-Citrullinated Protein Antibody Status and the Incidence of Erosive Disease in Patients with RA
Leslie R Harrold¹, Heather J. Litman², SE Connolly³, E Alemao³, Sabrina Rebello⁴, W Hua² and Joel Kremer⁵, ¹University of Massachusetts Medical School, Worcester, MA, ²Corrona, Southborough, MA, ³Bristol-Myers Squibb, Princeton, NJ, ⁴Corrona, LLC, Southborough, MA, ⁵Albany Medical College and The Center for Rheumatology, Albany, NY
Background/Purpose: RA is characterized by the production of autoantibodies including anti-citrullinated protein antibodies (ACPAs).1 ACPAs are considered a prognostic indicator for more severe RA and…
Abstract Number: 2918 • 2017 ACR/ARHP Annual Meeting
The Appearance of IgA RF Followed By IgG RF Is Associated with Transition to Classifiable RA in a Large Preclinical RA Cohort
Lindsay B. Kelmenson¹, Brandie D. Wagner², M. Kristen Demoruelle¹, V. Michael Holers¹, Ted R. Mikuls³, Jess D. Edison⁴ and Kevin D. Deane¹, ¹Rheumatology Division, University of Colorado Denver, Aurora, CO, ²Department of Biostatistics and Informatics, University of Colorado, Aurora, CO, ³Rheumatology, University of Nebraska Medical Center, Omaha, NE, ⁴Rheumatology Division, Walter Reed National Military Medical Center, Bethesda, MD
Background/Purpose: Autoantibodies including rheumatoid factor (RF) and antibodies to citrullinated protein antigens (ACPA) are known to be present in the serum of individuals prior to…
Abstract Number: 1035 • 2016 ACR/ARHP Annual Meeting
The Prognostic Value of Different Auto-Antibodies for Arthritis Development in Patients with Clinically Suspect Arthralgia
Robin M ten Brinck¹, Hanna W van Steenbergen¹, Marije K. Verheul¹, Leendert A. Trouw² and Annette HM van der Helm-van Mil³, ¹Department of Rheumatology, Leiden University Medical Center, Leiden, Netherlands, ²Rheumatology, Leiden University Medical Center, Leiden, Netherlands, ³Rheumatology, Rheumatology, Leiden University Medical Center, Leiden, Netherlands
Background/Purpose: Previous longitudinal studies in arthralgia patients studied Rheumatoid Factor (IgM-RF) and Anti-Citrullinated Protein Antibodies (ACPA) in relation to arthritis development. Participants in these studies…
Abstract Number: 1553 • 2016 ACR/ARHP Annual Meeting
Declining Flare Rates in the First Five Years of RA Disease, but Not after
Shafay Raheel¹, Cynthia S. Crowson², Eric L. Matteson¹ and Elena Myasoedova¹, ¹Rheumatology, Mayo Clinic, Rochester, MN, ²Health Sciences Research, Mayo Clinic, Rochester, MN
Background/Purpose: Flare or episodic worsening of disease activity is an important aspect of the disease experience for patients with rheumatoid arthritis (RA). Improving trends towards…
Abstract Number: 2654 • 2016 ACR/ARHP Annual Meeting
Association Between Rheumatoid Factor Positivity and Effects of Treatment with a First Biologic Agent in Rheumatoid Arthritis
Yoshikazu Ogawa¹, Nobunori Takahashi², Toshihisa Kojima³ and Naoki Ishiguro⁴, ¹orthopedic surgery, Sakashita Hospital, Nakatsugawa, Japan, ²Nagoya Univ. Grad. Schl. of Med., Nagoya, Japan, ³Department of Orthopedic Surgery, Nagoya University Hospital, Nagoya, Japan, ⁴Nagoya University, Nagoya, Japan
Background/Purpose: The presence of rheumatoid factor (RF) plays an important role in the diagnosis of rheumatoid arthritis (RA). However, whether RF positivity is related to…
Abstract Number: 501 • 2015 ACR/ARHP Annual Meeting
Change in RF Titers Reflects RA Disease Activity and Predicts Therapeutic Response during TNF Inhibitor Therapy; Patients with a Continuous Reduction of Serum RF Levels Show Good Response
Takayoshi Owada, Kazuhiro Kurasawa, Yuta Takamura, Yumeko Namiki, Ayae Tanaka, Ryutaro Yamazaki, Harutsugu Okada, Satoko Arai, Reika Maezawa, Keiko Hatanaka and Yoshiki Ishii, Clinical Immunology, Dokkyo Medical University, Mibu, Tochigi, Japan
Background/Purpose: Serum RF was detected in 26-90% of RA patients, and high-titer RF has been shown a poor prognosis factor in RA and predictor of…
Abstract Number: 520 • 2015 ACR/ARHP Annual Meeting
Antibody to Porphyromonas Gingivalis in Pre-Clinical Rheumatoid Arthritis
Brian Coburn¹, Kevin D. Deane², Jess D. Edison³, Geoffrey M. Thiele¹, Michael J. Duryee⁴, Carlos D. Hunter⁴, Jeffrey Payne⁵, Fang Yu⁶, Harlan Sayles⁶, V. Michael Holers², Jill M. Norris⁷, William R Gilliland⁸, Jeremy Sokolove⁹, WH Robinson⁹ and Ted R. Mikuls¹, ¹Omaha VA Medical Center and University of Nebraska Medical Center, Omaha, NE, ²Division of Rheumatology, University of Colorado School of Medicine, Aurora, CO, ³Walter Reed National Military Medical Center, Bethesda, MD, ⁴Internal Medicine Division of Rheumatology, University of Nebraska Medical Center, Omaha, NE, ⁵College of Dentistry, University of Nebraska Medical Center, Lincoln, NE, ⁶University of Nebraska Medical Center, Omaha, NE, ⁷Epidemiology, University of Colorado Denver, Aurora, CO, ⁸Rheumatology Service, Walter Reed National Military Medical Center, Bethesda, MD, ⁹VA Palo Alto Healthcare System and Stanford University, Palo Alto, CA
Background/Purpose: Periodontitis (PD) has been implicated as an etiologic risk factor in rheumatoid arthritis (RA), an association that is speculated to be related to the…
Abstract Number: 1216 • 2015 ACR/ARHP Annual Meeting
The Clinical and Ultrasonographic Presentation of Seronegative RA Is More Severe Compared to Seropositive RA in an Inception Cohort of DMARD-Naïve Patients Classified According to the 2010 ACR/EULAR Criteria
Lena B. Nordberg¹, Siri Lillegraven¹, Elisabeth Lie¹, Anna-Birgitte Aga², Inge C Olsen², Hilde Berner Hammer³, Till Uhlig¹, Désirée van der Heijde⁴, Tore K. Kvien¹, Espen A. Haavardsholm¹ and the ARCTIC Study Group, ¹Dept. of Rheumatology, Diakonhjemmet Hospital, Oslo, Norway, ²Department of Rheumatology, Diakonhjemmet Hospital, Oslo, Norway, ³Dept of Rheumatology, Diakonhjemmet Hospital, Oslo, Norway, ⁴Dept. of Rheumatology, Leiden University Medical Center, Leiden, Netherlands
Background/Purpose: The development of the 2010 ACR/EULAR classification criteria for rheumatoid arthritis (RA) has led to a redefinition of the patient population, including classification of…
Abstract Number: 1904 • 2014 ACR/ARHP Annual Meeting
Rheumatoid Factor Isotype Testing to Identify Individuals in the Preclinical Period of Rheumatoid Arthritis
M. Kristen Demoruelle¹, Anthony Kahr¹, Mark C. Parish¹, Marie L. Feser¹, Ryan W. Gan², Jason R. Kolfenbach¹, William R. Gilliland³, Jess D. Edison³, Michael H. Weisman⁴, James R. O'Dell⁵, Ted R. Mikuls⁶, Richard M. Keating⁷, Peter K. Gregersen⁸, Jane H. Buckner⁹, Jill M. Norris², V. Michael Holers¹⁰ and Kevin D. Deane¹, ¹Division of Rheumatology, University of Colorado School of Medicine, Aurora, CO, ²Epidemiology, Colorado School of Public Health, Aurora, CO, ³Walter Reed National Military Medical Center, Bethesda, MD, ⁴Rheumatology, Cedars-Sinai Medical Center, Los Angeles, CA, ⁵Veteran Affairs Nebraska Western Iowa Health Care System and University of Nebraska Medical Center, Omaha, NE, ⁶Omaha VA Medical Center and University of Nebraska Medical Center, Omaha, NE, ⁷Division of Rheumatology, Scripps Clinic, La Jolla, CA, ⁸Genomics and Human Genetics, Feinstein Institute for Medical Research, Manhasset, NY, ⁹Benaroya Research Institute at Virginia Mason, Seattle, WA, ¹⁰Rheumatology Division, University of Colorado School of Medicine, Aurora, CO
Background/Purpose: Rheumatoid arthritis (RA)-related autoantibody (Ab) testing for Abs to cyclic citrullinated peptide (CCP) and rheumatoid factor (RF) are used in the clinical diagnosis of…
Abstract Number: 2363 • 2013 ACR/ARHP Annual Meeting
Positivity Of Rheumatoid Factor and Anti-Cyclic Citrullinated Peptide Is Associated With The Response Rate Of Infliximab, But Not Tocilizumab, In Treatment Of Rheumatoid Arthritis
Masao Sato¹, Masao Takemura², Ryuki Shinohe¹, Yasuko Yamamoto³ and Kuniaki Saito³, ¹Orthopaedic Surgery, Gifu University, Gifu, Japan, ²Informative Clinical Medicine, Gifu University, Gifu, Japan, ³Human Health Science, Kyoto University, Kyoto, Japan
Background/Purpose: Recent reports have shown that positivity for rheumatoid factor (RF) and anti-citrullinated protein antibodies (ACPA) can influence the efficacy of rheumatoid arthritis (RA) treatment.…

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