ACR Meeting Abstracts

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Abstracts tagged "rheumatoid arthritis (RA) and tuberculosis"

  • Abstract Number: 1224 • 2018 ACR/ARHP Annual Meeting

    High Rates of Conversion and Reversion of Tuberculosis Screening Assays in Rheumatic Patients during Long Term Biologic Treatment

    Konstantinos Thomas1, Anastasia Makris1, Christina Tsalapaki1, Argyro Lazarini1, Kalliopi Klavdianou1, Katerina Antonatou1, Christos Koutsianas1, Chrisoula Hatzara1, Emilia Hadziyannis1 and Dimitrios Vassilopoulos2, 1Clinical Immunology-Rheumatology Unit, 2nd Department of Medicine and Laboratory, Hippokration General Hospital, Joint Rheumatology Program, National and Kapodistrian University of Athens, School of Medicine, Athens, Greece, 2Clinical Immunology-Rheumatology Unit, 2nd Department of Medicine and Laboratory, Hippokration General HospitalMedicine, Joint Rheumatology Program, National and Kapodistrian University of Athens, School of Medicine, Athens, Greece

    Background/Purpose: Baseline screening for tuberculosis (TB) with tuberculin skin testing (TST) and/or interferon-gamma release assays (IGRAs) is recommended for all rheumatic patients starting biologic DMARDs…
  • Abstract Number: 2787 • 2017 ACR/ARHP Annual Meeting

    Tuberculosis, Potential Opportunistic Infections, and Other Infections of Interest in Patients with Moderate to Severe Rheumatoid Arthritis in the Baricitinib Program

    Kevin Winthrop1, Stephen Lindsey2, Masayoshi Harigai3, John D. Bradley4, Lei Chen4, David L. Hyslop4, Maher Issa4, Atsushi Nishikawa5, Sarah Witt4, Christina L. Dickson4 and Maxime Dougados6, 1Oregon Health & Science University, Portland, OR, 2Ochsner Health Center, Baton Rouge, LA, 3Division of Epidemiology and Pharmacoepidemiology of Rheumatic Diseases, Institute of Rheumatology, Tokyo Women's Medical University, Tokyo, Japan, 4Eli Lilly and Company, Indianapolis, IN, 5Lilly Japan K.K., Kobe, Japan, 6Rene Descartes University, Cochin Hospital, Paris, France

    Background/Purpose: Baricitinib (bari) is an oral selective Janus kinase (JAK) 1 and JAK2 inhibitor approved in the EU for the treatment (trt) of moderately to…
  • Abstract Number: 997 • 2017 ACR/ARHP Annual Meeting

    Incidence and Clinical Characteristics of Active Tuberculosis in a Cohort of Patients with Inflammatory Arthritis Treated with TNF-Inhibitors

    Ana Maria Gheorghiu1, Alexandru Garaiman2, Alexandra Radu2, Alina Soare3, Victoria Arama4, Dragos Bumbacea5, Rucsandra Dobrota6, Raida Oneata7, Simona Pintilie2, Mihaela Milicescu7, Ioan Ancuta7, Andrei Martin2, Mariana Sasu1, Claudia Ciofu1, Liviu Macovei1, Victor Stoica7, Mihai Bojinca7 and Carina Mihai8, 1Carol Davila University of Medicine and Pharmacy,Internal Medicine and Rheumatology Department ,,Dr.I.Cantacuzino'' Clinical Hospital, Bucharest, Romania, 2Internal Medicine and Rheumatology, CANTACUZINO HOSPITAL, Carol Davila University of Medicine and Pharmacy, Bucharest, Romania, 3Department of Internal Medicine 3 – Rheumatology and Immunology, Universitätsklinikum Erlangen, Friedrich-Alexander-University Erlangen-Nürnberg (FAU), Erlangen, Germany, 4Infectious Diseases 1 Department, Matei Bals National Institute for Infectious Diseases, Carol Davila University of Medicine and Pharmacy, Bucharest, Romania, 5Department of Pneumology, Elias Emergency University Hospital, Carol Davila University of Medicine and Pharmacy, Bucharest, Romania, 6Department of Rheumatology, Center of Experimental Rheumatology, University Hospital Zurich, Zurich, Switzerland, 7Carol Davila University of Medicine and Pharmacy, Internal Medicine and Rheumatology Department, Cantacuzino Clinical Hospital, Bucharest, Romania, 8Internal Medicine and Rheumatology Dept., Cantacuzino Clinical Hospital, Carol Davila University of Medicine and Pharmacy, Bucharest, Romania

    Background/Purpose: Tuberculosis (TB) is a major concern in patients receiving TNF inhibitors (TNFi). Objectives: To assess the incidence of active TB and the efficacy of…
  • Abstract Number: 1089 • 2017 ACR/ARHP Annual Meeting

    Large Variations in Tuberculosis Testing for New Biologic Users with Rheumatoid Arthritis Among Providers in the RISE Registry

    Gabriela Schmajuk1, Michael Evans2, Julia Kay3 and Jinoos Yazdany4, 1San Francisco VA Medical Center, University of California San Francisco, San Francisco, CA, 2University of California San Francisco, San Francisco, CA, 3Medicine/Rheumatology, University of California - San Francisco, San Francisco, CA, 4Medicine/Rheumatology, University of California San Francisco, San Francisco, CA

    Background/Purpose: Tuberculosis (TB) testing prior to biologic DMARD use helps prevent potentially fatal, medication-related adverse events and is a National Quality Forum-endorsed quality measure. We…
  • Abstract Number: 1507 • 2016 ACR/ARHP Annual Meeting

    Our Strategy of Preventing Tuberculosis (TB) in Patients with Rheumatic Diseases Under the Treatment with Biologic Dmards

    Shinji Motojima1, Tamao Nakashita2, Akira Jibatake1, Akira Yoshida1 and Yoshiki Yamamoto1, 1Department of Rheumatology and Allergy, Kameda Medical Center, Kamogawa city, Japan, 2Department of Rheumatology and Allergy, Kameda Medical Center, Kamogawa-city, Japan

    Background/Purpose: According to the report by WHO, Japan is still in moderately-prevailing countries of TB. The annual incidence of TB in Japan is approximately 15/100,000,…
  • Abstract Number: 1518 • 2016 ACR/ARHP Annual Meeting

    Immunoglobulin Binding Protein (BiP), an Antigen for CCP Sero-Positive Rheumatoid Arthritis Patients, Can Result in a False Positive Quantiferon-Gold Tuberculosis Test

    JoAnn Ball1, Kelsy Greenwald1, Atul A. Deodhar2 and Kevin L. Winthrop3, 1Rheumatology, Desert Medical Advances, Palm Desert, CA, 2Division of Arthritis & Rheumatic Diseases OP09, Oregon Health & Science University, Portland, OR, 3Oregon Health and Sciences University, Portland, OR

    Background/Purpose: Citrullinated BiP is a newly described target for cyclic citrullinated peptide(CCP).  BiP in both serum and synovial fluid is over-expressed in RA patients and…
  • Abstract Number: 1525 • 2015 ACR/ARHP Annual Meeting

    Detection of Previous Tuberculosis Infections in Japanese Rheumatoid Arthritis Patients: Comparison of Two Interferon-G Releasing Assays and the Impact of CD4-Positive Lymphocytes

    Shogo Banno1, Shiho Iwagaitsu2, Taio Naniwa3, Hironobu Nobata4, Hirokazu Imai4, Shinya Tamechika2, Shinji Maeda2 and Akio Niimi2, 1Rheumatology and Nephrology, Aichi Medical University School of Medicine, Aichi-prefecture, Japan, 2Allergy, Respiratory Medicine and Immunology, Nagoya City University Graduate School of Medical Science, Nagoya City, Japan, 3Allergy, Respiratory Medicine and Immunology, Nagoya City University Graduate School of Medical Science, Nagoya city, Japan, 4Rheumatology and Nephrology, Aichi Medical University School of Medicine, Nagakute City, Japan

    Background/Purpose: We aimed to evaluate the performance of QFT-GIT and T-SPOT.TB assays to predict the risk of latent tuberculosis infection (LTBI) in Japanese rheumatoid arthritis…
  • Abstract Number: 2142 • 2015 ACR/ARHP Annual Meeting

    Comparison of Interferon-y Release Assay Versus Tuberculin Skin Test in the Golimumab UC and the Golimumab SC Rheumatology (RA, PsA, and AS) Clinical Study Programs

    Elizabeth C. Hsia1,2, Neil Schluger3, John J. Cush4, Eric L. Matteson5, Stephen Xu1, William Sandborn6, Paul Rutgeerts7 and Colleen Marano1, 1Janssen Research & Development, LLC, Spring House, PA, 2University of Pennsylvania, Philadelphia, PA, 3Columbia U College of Physicians & Surgeons, New York, NY, 4Baylor Research Institute, Dallas, TX, 5Division of Rheumatology, Department of Internal Medicine and Department of Health Sciences Research, Mayo Clinic, Rochester, MN, 6Inflammatory Bowel Disease Center, Division of Gastroenterology, Department of Medicine, University of California San Diego, La Jolla, California, La Jolla, CA, 7University Hospital Gasthuisberg, Leuven, Belgium

    Background/Purpose:   Interferon-ƴ release assays (IGRAs) offer the possibility of an improved method to detect TB infections in pts with autoimmune disorders.  Compare results of…
  • Abstract Number: 1697 • 2013 ACR/ARHP Annual Meeting

    Are Patients With Rheumatoid Arthritis Still At An Increased Risk Of Tuberculosis and What Is The Role Of Biological Treatment?

    Elizabeth V. Arkema1, Jerker Jonsson2, Eva Baecklund3, Maud Rutting4, Judith Bruchfeld5, Nils Feltelius4 and Johan Askling1,6, 1Clinical Epidemiology Unit, Department of Medicine, Karolinska Institutet, Stockholm, Sweden, 2Swedish Institute for Communicable Disease Control, Solna, Sweden, 3Department of Medical Sciences, Rheumatology, Uppsala University Hospital, Uppsala, Sweden, 4Swedish Medical Products Agency, Uppsala, Sweden, 5Department of Medicine, Infectious Diseases Unit, Karolinska Institutet, Stockholm, Sweden, 6Rheumatology Unit, Karolinska University Hospital, Stockholm, Sweden

    Background/Purpose:   Anti-TNF therapy is a risk factor for clinical tuberculosis (TB), which has led to pre-treatment screening and increased vigilance. The extent to which…
  • Abstract Number: 1367 • 2013 ACR/ARHP Annual Meeting

    Performance Of a Two-Step Latent Tuberculosis Screening Algorithm In Patients With Rheumatoid Arthritis, Psoriatic Arthritis Or Ankylosing Spondylitis Prior To Treatment With Tumor Necrosis Alpha Inhibitors: Prospective Observational Data From The Biorx.Si Registry

    ŽIga Rotar1 and Matija Tomsic2, 1Department of Rheumatology, University Medical Centre Ljubljana, Ljubljana, Slovenia, 2Department of Rheumatology, University Medical Centre Ljubjana, Ljubljana, Slovenia

    Background/Purpose: Reactivation of latent tuberculosis infection (LTBI) is of concern in patients treated with TNFi. Conversely, TB chemoprophylaxis (CP) is time consuming, delays the initiation…
  • Abstract Number: 1138 • 2013 ACR/ARHP Annual Meeting

    Tuberculin Skin Test and Booster Phenomenon In a Rheumatoid Arthritis Population. Differences Between Early and Established Disease

    Lorena Perez-Barbosa1, David Vega-Morales2, Janett Carmen Luzmilla Riega-Torres1, Octavio Ilizaliturri-Guerra1 and Mario Alberto Garza-Elizondo1, 1Early Arthritis Clinic, Rheumatology Service, Hospital Universitario, Monterrey, Mexico, 2Rheumatology, Hospital Universitario UANL, Monterrey, Mexico

    Background/Purpose: Tuberculosis (TB) remains a major global health problem.   Chronic inflammation in Rheumatoid Arthritis (RA) and the use of immunosuppressive drugs, increase the risk of…
  • Abstract Number: 1641 • 2012 ACR/ARHP Annual Meeting

    When Can Biological Therapy Be Resumed in Patients with Rheumatic Conditions Who Develop Tuberculosis Infection During Tumour Necrosis Factors Antagonists Therapy? Study Based On the Biobadaser Data Registry

    Maria Victoria Hernández1, Miguel A. Descalzo2, Juan D. Cañete1, Raimon Sanmarti3 and BIOBADASER Study Group4, 1Rheumatology, Hospital Clínic of Barcelona. IDIBAPS. University of Barcelona, Barcelona, Spain, 2Research Unit, Spanish Society of Rheumatology, Madrid, Spain, 3Arthritis Unit. Rheumatology Department, Hospital Clínic of Barcelona, Barcelona, Spain, 4Research Unit. Spanish Society of Rheumatology, Madrid, Spain

    Background/Purpose: Tuberculosis infection (TI) is one of the most serious adverse events related to tumour necrosis factor (TNF) antagonists. According to the current treatment guidelines…
  • Abstract Number: 173 • 2012 ACR/ARHP Annual Meeting

    Latent Tuberculosis Screening and Treatment in Rheumatoid Arthritis Patients Eligible for Anti-TNF Therapy in Endemic Areas: Does It Work?

    Ieda Laurindo1, Ana C. M. Ribeiro1, Julio C. B. Moraes2, Carla G.S. Saad1, Karina Rossi Bonfiglioli3, Fernando H.C. Souza3, Ana L. G. Calich1, Mariana G. Waisberg1, Lissiane K. N. Guedes3 and Eloisa Bonfa1, 1Rheumatology, Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil, 2Reumatologia, Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil, 3Rheumatology Division, Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil

    Background/Purpose: Background: Current recommendations for latent tuberculosis infection (LTB) screening and treatment in patients eligible for anti-TNF agents are not well established in endemic regions.…
  • Abstract Number: 177 • 2012 ACR/ARHP Annual Meeting

    Antibodies to Citrullinated Peptides in Tuberculosis

    Isabella Lima1, Rodrigo Oliveira2, Ajax Atta2, Samyra Marchi3, Lúcio Barbosa3, Eliana Reis3, Mitermayer G. Reis3 and Mittermayer Santiago4, 1Escola Bahiana de Medicina e Saúde Pública, Salvador, Brazil, 2Universidade Federal da Bahia, Salvador, Brazil, 3Fundação Oswaldo Cruz, Salvador, Brazil, 4Brazilian Registry of Spondyloarthritis, São Paulo, Brazil

    Background/Purpose: Rheumatoid arthritis (RA) is an autoimmune disease characterized by symmetric polyarthritis, rheumatoid factor positivity (RF) in the majority of patients, and bone erosions shown…
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All abstracts accepted to ACR Convergence are under media embargo once the ACR has notified presenters of their abstract’s acceptance. They may be presented at other meetings or published as manuscripts after this time but should not be discussed in non-scholarly venues or outlets. The following embargo policies are strictly enforced by the ACR.

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