Abstracts tagged "rheumatoid arthritis (RA) and treatment options"

Abstract Number: 2474 • 2014 ACR/ARHP Annual Meeting
Efficacy and Tolerability of Subcutaneous Methotrexate for Inflammatory Arthritis: A Retrospective Observational Cohort Study
Jessica Gunn, Aikaterina Panopolou and Alan Steuer, Rheumatology, Wexham Park Hospital, Slough, United Kingdom
Background/Purpose: Methotrexate (MTX) monotherapy or MTX in combination with other conventional and biologic disease-modifying antirheumatic drugs (DMARDs) is standard treatment for patients with inflammatory arthritis.…
Abstract Number: 1693 • 2013 ACR/ARHP Annual Meeting
Initial Triple DMARD Therapy Is More Efficient Than Methotrexate Monotherapy In Recent Onset Rheumatoid Arthritis; 1-Year Data Of a Randomized Clinical Trial (tREACH)
P.H.P. de Jong¹, J.M.W. Hazes², K.H. Han³, A.M. Huisman⁴, D. van Zeben⁵, P.A. van der Lubbe⁶, A.H. Gerards⁶, B. van Schaeybroeck⁷, P.B. de Sonnaville⁸, M.V. Krugten⁹, J.J. Luime² and A.E.A.M. Weel³, ¹Department of Rheumatology, Erasmus University Medical Center, Rotterdam, Netherlands, ²Rheumatology, Erasmus University Medical Center, Rotterdam, Netherlands, ³Rheumatology, Maasstad Hospital, Rotterdam, Netherlands, ⁴Rheumatology, Sint Franciscus Gasthuis, Rotterdam, Netherlands, ⁵Department of Rheumatology, Sint Franciscus Gasthuis, Rotterdam, Netherlands, ⁶Department of Rheumatology, Vlietland Hospital, Schiedam, Netherlands, ⁷Rheumatology, Albert Schweitzer Hospital, Dordrecht, Netherlands, ⁸Department of Rheumatology, Admiraal de Ruyter hospital, Goes, Netherlands, ⁹Department of Rheumatology, Admiraal de Ruyter Hospital, Vlissingen, Netherlands
Background/Purpose: Recommended treatment for DMARD naïve patients is methotrexate (MTX) with or without glucocorticoids (GCs). Triple DMARD therapy however is not recommended, because well proven…
Abstract Number: 1419 • 2013 ACR/ARHP Annual Meeting
Mode Of Action Change Not Necessary After Failing The First Tumornecrosisfactor Inhibitor: Preliminary Results Of a Randomized Controlled Trial
Sofie H.M. Manders¹, Wietske Kievit², Herman L.M. Brus³, Hein J. Bernelot Moens⁴, Andre Hartkamp⁵, Reinhard Bos⁶, Elisabeth Brouwer⁷, Henk Visser⁸, Harald E. Vonkeman⁹, Rene Westhovens¹⁰, Mart A.F.J. van de Laar¹¹ and Piet LCM Van Riel¹, ¹Radboud University Nijmegen Medical Centre, Nijmegen, Netherlands, ²Department of Rheumatology and DREAM registry, Radboud University Nijmegen Medical Centre, Nijmegen, Netherlands, ³TweeSteden Ziekenhuis, Tilburg, Netherlands, ⁴Ziekenhuisgroep Twente, Almelo, Netherlands, ⁵Reumatology, Jeroen Bosch Hospital, 's-Hertogenbosch, Netherlands, ⁶Rheumatology, Medical Center Leeuwarden, Leeuwarden, Netherlands, ⁷Rheumatology and Clinical Immunology, University of Groningen, University Medical Center Groningen, Groningen, Netherlands, ⁸Rheumatology, Rijnstate, Arnhem, Netherlands, ⁹Medisch Spectrum Twente & University of Twente, Enschede, Netherlands, ¹⁰Rheumatology, University Hospital KU Leuven, Leuven, Belgium, ¹¹Rheumatology, Medisch Spectrum Twente & University of Twente, Enschede, Netherlands
Background/Purpose: The best treatment option after a patient has failed a first TNFi is still unknown. Therefore the objective of this randomized open label study…
Abstract Number: 1346 • 2013 ACR/ARHP Annual Meeting
Drug Free Holiday In Patients With Rheumatoid Arthritis (RA): patients’ Opinion
I.M. Markusse, G. Akdemir, T.W.J. Huizinga and C.F. Allaart, Rheumatology, Leiden University Medical Center, Leiden, Netherlands
Background/Purpose: Clinical trials have shown that in many patients tapering and/or stopping antirheumatic medication is a realistic option. We interviewed patients to investigate their opinions,…
Abstract Number: 1050 • 2013 ACR/ARHP Annual Meeting
Population-Based Analysis Of Treatment Patterns For Recently Diagnosed Rheumatoid Arthritis Patients In The United States
Martin M. Crane¹, Boyka Stoykova², Julie Priest¹, Nasha Wang¹, Henry Krzywy¹ and Rahul Ganguly³, ¹WW Epidemiology, GlaxoSmithKline, Durham, NC, ²Global Health Outcomes, GlaxoSmithKline, Uxbridge, United Kingdom, ³Global Health Outcomes, GlaxoSmithKline, Durham, NC
Background/Purpose: As treatment paradigms for rheumatoid arthritis (RA) continue to evolve, population-based studies can help assess which strategies are being used in “real-world” practice for…
Abstract Number: 1722 • 2012 ACR/ARHP Annual Meeting
Exploring How Patients with Rheumatoid Arthritis Use a Methotrexate Decision Aid for Making Treatment Choices
Linda C. Li¹, Anne F. Townsend², Paul M. Adam³, Catherine L. Backman⁴, Sydney Brooks⁵, Gwen A. Ellert⁶, Allyson Jones⁷, Otto Kamensek⁸, Cheryl Koehn⁹, Diane Lacaille⁸, Jenny Leese², Colleen Maloney⁸, Elaine Yacyshyn¹⁰, Charlene Yousefi⁸ and Dawn Stacey¹¹, ¹Department of Physical Therapy, University of British Columbia, Vancouver, BC, Canada, ²Rheumatology, Arthritis Research Centre of Canada, Richmond, BC, Canada, ³Rheumatology Liaison, Mary Pack Arthritis Centre, Vancouver, BC, Canada, ⁴Occupational Science & Occupational Therapy, The University of British Columbia, Vancouver, BC, Canada, ⁵The Arthritis Society, Ontario Division, Toronto, ON, Canada, ⁶Health Education, Trelle Enterprises Inc, Vancouver, BC, Canada, ⁷Department of Physical Therapy, University of Alberta, Edmonton, AB, Canada, ⁸Arthritis Research Centre of Canada, Vancouver, BC, Canada, ⁹Arthritis Consumer Experts, Vancouver, BC, Canada, ¹⁰562 Heritage Med Rsch Ctr, University of Alberta, Edmonton, AB, Canada, ¹¹School of Nursing, University of Ottawa, Ottawa, ON, Canada
Background/Purpose: For patients with rheumatoid arthritis (RA), making treatment decisions can be overwhelming. The literature describes a sense of ambivalence among patients with chronic diseases…
Abstract Number: L7 • 2012 ACR/ARHP Annual Meeting
Tapering TNF-Blockers in Established Rheumatoid Arthritis Patients in DAS28 Remission: Results of a DAS28-Driven Step-Down Strategy Randomized Controlled Trial
Bruno Fautrel¹, Thao Pham², Florence Tubach³, Toni Alfaiate⁴, Jacques Morel⁵, Emmanuelle Dernis⁶, Xavier J. Puechal⁷, Philippe Gaudin⁸ and Xavier Mariette⁹, ¹Rheumatology, UPMC - Paris 6 University, Paris, France, ²Rheumatology Department, Sainte Marguerite Hospital, Marseille, France, ³Département d'Epidémiologie Biostatistique et Recherche Clinique, APHP, Hôpital Bichat, Paris, France, ⁴Biostatistics, Bichat Hospital, AP-HP, Paris, France, ⁵Dpartment of Rheumatology, Lapeyronie Hospital, Montpellier, France, ⁶Centre Hospitalier, Le Mans, France, ⁷Le Mans Hospital, Le Mans, France, ⁸Rheumatology Department, CHU Hôpital Sud, Grenoble Teaching Hospital, Echirolles, France, ⁹Rheumatology Service, Bicêtre University Hospital, Le Kremlin Bicetre, France
Background/Purpose: Step-down therapeutic strategies are often considered in established rheumatoid arthritis (RA) once remission is achieved but are associated with a potential risk of relapse…

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