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Abstracts tagged "rheumatoid arthritis (RA) and statins"

  • Abstract Number: 11 • ACR/ARHP Annual Meeting 2016

    Drug Prescribing Trends in Adults with Rheumatoid Arthritis: A Population-Based Comparative Study from 2005-2014

    Alex Zamora-Legoff1, Cynthia S. Crowson2, Eric L. Matteson3, Sara J. Achenbach4 and Elena Myasoedova3, 1Division of Rheumatology, Mayo Clinic, Rochester, MN, 2Health Sciences Research, Mayo Clinic, Rochester, MN, 3Rheumatology, Mayo Clinic, Rochester, MN, 4Department of Health Sciences Research, Mayo Clinic, Rochester, MN

    Background/Purpose:  To examine drug prescribing trends for patients with rheumatoid arthritis (RA) over recent years and compare them to matched non-RA subjects. Methods: Retrospective prescription…
  • Abstract Number: 3023 • ACR/ARHP Annual Meeting 2016

    Lipid Profile and Effect of Statin Treatment in Pooled Phase 2 and Phase 3 Baricitinib Studies

    Iain B. McInnes1, Joel Kremer2, Paul Emery3, Steven H. Zuckerman4, Giacomo Ruotolo4, Chadi Saifan4, Lei Chen4, Shayami Thanabalasundrum4, Sarah Witt4 and William Macias4, 1Institute of Infection, Immunity and Inflammation, University of Glasgow, Glasgow, Great Britain, 2The Center for Rheumatology, Albany Medical College, Albany, NY, 3University of Leeds, Midlothian, United Kingdom, 4Eli Lilly and Company, Indianapolis, IN

    Background/Purpose: In patients with active RA an increase in lipid analytes has been observed after treatment with janus kinase inhibitors and other disease-modifying antirheumatic drugs.1…
  • Abstract Number: 591 • ACR/ARHP Annual Meeting 2015

    Rosuvastatin Improves Endothelial Function in Patients with Inflammatory Joint Diseases, Longitudinal Associations with Atherosclerosis and Arteriosclerosis

    Eirik Ikdahl1, Jonny Hisdal2, Silvia Rollefstad1, Inge C Olsen3, Tore K. Kvien4, Terje R. Pedersen5 and Anne Grete Semb6, 1Preventive Cardio-Rheuma Clinic, Department of Rheumatology, Diakonhjemmet Hospital, Oslo, Norway, 2Section of Vascular Investigations, Oslo University Hospital Aker, Oslo, Norway, 3Department of Rheumatology, Diakonhjemmet Hospital, Oslo, Norway, 4Dept. of Rheumatology, Diakonhjemmet Hospital, Oslo, Norway, 5Department of Preventive Cardiology, Ullevaal University Hospital, Oslo, Norway, 6Preventive Cardio-Rheuma clinic, Department of Rheumatology, Diakonhjemmet Hospital, Oslo, Norway

    Background/Purpose: Endothelial dysfunction is an early step in the formation of atherosclerotic lesions and can be quantified by the degree of flow mediated vasodilation (FMD)…
  • Abstract Number: 1502 • ACR/ARHP Annual Meeting 2015

    Initiating Statin Medication and Risk of Fatigue in Rheumatoid Arthritis

    James S. Andrews1, Harlan Sayles2, Kaleb Michaud3 and Patricia P. Katz4, 1Rheumatology, University of California San Francisco, San Francisco, CA, 2University of Nebraska Medical Center, Omaha, NE, 3Internal Medicine, University of Nebraska Medical Center, Omaha, NE, 4Rheumatology, UCSF, SF, CA

    Background/Purpose: Fatigue is common in Rheumatoid Arthritis (RA) and has a major impact on quality of life. Individuals with RA are also at increased risk…
  • Abstract Number: 2126 • ACR/ARHP Annual Meeting 2015

    Trial of Atorvastatin for the Primary Prevention of Cardiovascular Events in Patients with Rheumatoid Arthritis

    George D. Kitas1, Peter Nightingale2, Jane Armitage3, Naveed Sattar4, Jill Belch5, Deborah P.M. Symmons6 and TRACE RA Consortium, 1Dudley Group NHS Foundation Trust, Dudley, and Arthritis Research Campaign Epidemiology Unit, University of Manchester, Manchester, United Kingdom, 2Wolfson Computer Laboratory, University Hospitals Birmingham NHS Foundation Trust, Birmingham, United Kingdom, 3Clinical Trial Service Unit and Epidemiology Unit, University of Oxford, Oxford, United Kingdom, 4University of Glasgow, BHF Glasgow Cardiovascular Research Centre, Glasgow, United Kingdom, 5Division of Cardiovascular and Diabetes Medicine, University of Dundee, Dundee, United Kingdom, 6NIHR Manchester Musculoskeletal Biomedical Research Unit, Central Manchester University Hospitals NHS Foundation Trust, Manchester, United Kingdom

    Background/Purpose: Patients with rheumatoid arthritis (RA) are at increased risk for cardiovascular disease (CVD) compared to the general population, both due to classical and novel…
  • Abstract Number: 2829 • ACR/ARHP Annual Meeting 2013

    Statin Adherence and Risk Of Mortality In Patients With Rheumatoid Arthritis: A Population-Based Study

    Mary De Vera1,2, Michal Abrahamowicz3 and Diane Lacaille4, 1Faculty of Pharmaceutical Sciences, University of British Columbia, Vancouver, BC, Canada, 2Arthritis Research Centre of Canada, Richmond, BC, Canada, 3Division of Clinical Epidemiology, McGill University, Montreal, QC, Canada, 4Rheumatology, Arthritis Research Centre of Canada, University of British Columbia, Richmond, BC, Canada

    Background/Purpose: Poor adherence with statin therapy is associated with increased mortality in the general population, but no corresponding data are available among patients with rheumatoid…
  • Abstract Number: 2765 • ACR/ARHP Annual Meeting 2013

    A Double-Blind Randomized Placebo-Controlled Trial Of Lovastatin in Patients with Rheumatoid Arthritis

    Cynthia Aranow1, John J. Cush2, Marcy B. Bolster3, Christopher C. Striebich4, Maria Dall'era5, Meggan Mackay6, Ewa Olech7, Tracy M. Frech8, J. Box9, Richard M. Keating10, Mary Chester M. Wasko11, E. William St Clair12, Alan Kivitz13, Betty Diamond14, Anne Davidson15, Meagan Spychala16, Ellen A. Goldmuntz17 and Autoimmunity Centers of Excellence18, 1Feinstein Institute for Medical Research, Manhasset, NY, 2Baylor Research Institute and Baylor University Medical Center, Dallas, TX, 3Medicine, Medical University of South Carolina, Charleston, SC, 4University of Colorado Denver, Aurora, CO, 5Medicine/Rheumatology, University of California, San Francisco, San Francisco, CA, 6Autoimmune & Musculoskeletal Disease, Feinstein Institute for Medical Research, Manhasset, NY, 7Clinical Pharmacology, Oklahoma Medical Research Foundation, Oklahoma City, OK, 8Internal Medicine-Division of Rheumatology, University of Utah School of Medicine, SLC, UT, 9Carolina Bone and Joint, Charlotte, NC, 10Rheumatology Section, The University of Chicago, Chicago, IL, 11West Penn Allegheny Health System, Temple University School of Medicine, Pittsburgh, PA, 12Medicine, Duke Unversity Medical Center, Durham, NC, 13Altoona Center for Clinical Research, Duncansville, PA, 14Autoimmune & Musculoskeletal, Feinstein Institute for Medical Research, Manhasset, NY, 15Autoimmunity and Musculoskeletal Diseases, Feinstein Institute for Medical Research, Manhasset, NY, 16Rho, Inc., Chapel Hill, NC, 17DAIT, NIAID/NIH, Bethesda, MD, 18NIAID, National Institutes of Health, Bethesda, MD

    Background/Purpose: HMG -CoA reductase inhibitors (statins) are standard treatment for hyperlipidemia. In addition to lipid lowering abilities, statins exhibit multiple anti-inflammatory effects.   The objectives of…
  • Abstract Number: 1249 • ACR/ARHP Annual Meeting 2012

    The Impact of Statin Use On Lipid Levels in Statin-Naive Patients with Rheumatoid Arthritis (RA) Vs. Non-RA Subjects: Results From a Population-Based Study

    Elena Myasoedova1, Cynthia S. Crowson2, Abigail B. Green2, Eric L. Matteson3 and Sherine E. Gabriel4, 1Internal Medicine and Rheumatology, Mayo Clinic, Rochester, MN, 2Department of Health Sciences Research, Mayo Clinic, Rochester, MN, 3Rheumatology, Mayo Clinic, Rochester, MN, 4Health Sciences Research & Div of Rheumatology, Mayo Clinic, Rochester, MN

    Background/Purpose: Dyslipidemia in patients with rheumatoid arthritis (RA) is well recognized. The impact of lipid-lowering medications on lipid levels in patients with RA vs non-RA…

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