Abstracts tagged "rheumatoid arthritis (RA) and B cell targeting"

Abstract Number: 967 • 2019 ACR/ARP Annual Meeting
Bruton’s Tyrosine Kinase (BTK) Pathway Is Active in Synovium at Various Stages of Rheumatoid Arthritis Disease Progression
Sunil Nagpal¹, Qingxuan Song ², Matthew Loza ³, Yanqing Chen ⁴, Xuefeng Yin ², Leon Cheng ⁴, Michael Huber ⁴, Frédéric Baribaud ³, Fang Shen ¹ and Navin Rao ¹, ¹Janssen R&D, Spring House, PA, ²Janssen R&D, Spring House, ³Janssen Research & Development, LLC, Spring House, PA, ⁴Janssen Research, La Jolla
Background/Purpose: Bruton’s tyrosine kinase (BTK), a TEC family non-receptor kinase, is expressed in B cells and myeloid cells. BTK relays signaling downstream of B cell…

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Abstracts tagged "rheumatoid arthritis (RA) and B cell targeting"

Bruton’s Tyrosine Kinase (BTK) Pathway Is Active in Synovium at Various Stages of Rheumatoid Arthritis Disease Progression