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Abstracts tagged "Response Criteria"

  • Abstract Number: 0309 • ACR Convergence 2024

    Characteristics and Factors Associated with Treatment Response Among Patients with Eosinophilic Fasciitis: A Systematic Review and Meta-analysis

    Omar Hamdan1, Roa'a Alshajrawi1, Qais Mussa1, Yazeed Alajlouni1, Yazan Dabbah1, Rawan Fratekh1, Yousef Al-Mabrouk2, Shatha Al-Mabrok2 and Ahmad A. Toubasi1, 1University of Jordan, Amman, Jordan, 2Mansoura University, Al Mansoura, Egypt

    Background/Purpose: To date, data on the clinical features, diagnosis and the treatment of Eosinophilic Fasciitis (EF) patients are mostly derived from individual case reports, with…
  • Abstract Number: 0636 • ACR Convergence 2024

    Evaluation of Clinical, Histological and Biomarker Response After Induction Treatment of Lupus Nephritis (LN)

    Danielle Egypto1, Edgard Reis Neto2, Guilherme Carlesso3, Luis Andrade4, Luiz Moura3, Debora Calderaro5 and Emília Sato6, and Emília Inoue Sato; Edgar Torres dos Reis Neto., 1Federal University of Paraiba, JOÃO PESSOA, Paraiba, Brazil, 2Division of Rheumatology, Department of Medicine, Escola Paulista de Medicina, Universidade Federal, São Paulo, SP, Brazil, 3Federal University of São Paulo, São Paulo, SP, Brazil, 4Division of Rheumatology, Department of Medicine, Escola Paulista de Medicina, Federal University of São Paulo, São Paulo, SP, Brazil, 5Federal University of Minas Gerais, Belo Horizonte, Minas Gerais, Brazil, 6Universidade Federal de Sao Paulo, São Paulo, SP, Brazil

    Background/Purpose: LN occurrs in 50 to 75 percent of SLE patients and is associated with a significant morbimortality. LN presents distinct severity, with frequent flares…
  • Abstract Number: 1162 • ACR Convergence 2024

    Evaluating the Efficacy of Rituximab in the Treatment of Refractory Adult Idiopathic Inflammatory Myositis Using Total Improvement Score: Data from a Real-World Multi-Centre Registry in the United Kingdom

    Xia Lyu1, Patrick Gordon2, Harsha Gunawardena3, Neil McHugh4, Sarah Tansley4, Athiveeraramapandian Prabu5, Peter Lanyon6, James Miller7, Voon Ong8, Anthony Isaacs9, Chee-Seng Yee10, Caroline Cotton11, Patrick Kiely12, Eleni Stathopoulou13, James Taylor14, Rachel Jeffery14, Anurag Bharadwaj15, James Lilleker16, Janine Lamb17 and hector Chinoy18, and MYOPROSP consortium, 1Department of Rheumatology, Renji Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, Shanghai, China (People's Republic), 2nhs, London, United Kingdom, 3North Bristol NHS Trust, and Academic Rheumatology, University of Bristol, Bath, United Kingdom, 4University of Bath, Bath, United Kingdom, 5Sandwell and West Birmingham Hospitals NHS Trust, Birmingham, United Kingdom, 6Nottingham University Hospitals NHS Trust, and Lifespan and Population Health, School of Medicine, University of Nottingham, Nottingham, United Kingdom, 7Department of Neurology, Royal Victoria Infirmary, Newcastle upon Tyne Hospitals NHS Foundation Trust, Newcastle, United Kingdom, 8University College London, London, England, United Kingdom, 9Department of Rheumatology, London North West University Healthcare NHS Trust, London, United Kingdom, 10Department of Rheumatology, Doncaster and Bassetlaw Teaching Hospitals NHS Foundation Trust, Doncaster, United Kingdom, 11Department of Rheumatology, Liverpool University Hospitals NHS Foundation Trust, Liverpool, United Kingdom, 12Department of Rheumatology, St George's University Hospitals NHS Foundation Trust, London, United Kingdom, 13Department of Rheumatology, Solihull Hospital, University Hospitals of Birmingham NHS FT, Birmingham, United Kingdom, 14Department of Rheumatology, Northampton General Hospital, Northampton General Hospital NHS Trust, Northampton, United Kingdom, 151Basildon University Hospital, Mid & South Essex NHS Foundation Trust, Rheumatology, Basildon, United Kingdom, Basildon, United Kingdom, 16Northern Care Alliance NHS Trust, Salford, United Kingdom, 17University of Manchester, UK, Manchester, United Kingdom, 18The University of Manchester, Manchester, United Kingdom

    Background/Purpose: B cell depletion in the form of rituximab (RTX) is an established treatment modality for idiopathic inflammatory myopathies (IIM). Treatment response is now assessed…
  • Abstract Number: 1341 • ACR Convergence 2024

    Evaluation of Width Range Index (WRI) and Neutrophil-to-Lymphocyte Ratio (NLR) in Assessing Disease Activity in Patients with Rheumatoid Arthritis

    Santiago Dans Caballero1, Marta Rojas Giménez2, Clementina López Medina3, Andrea Cid Chaves2, Mónica Rico-Muñoz3, mitndbaim aelohim parra Moreno2 and Alejandro Escudero-Contreras4, 1Reina Sofia University Hospital, Lebrija, Andalucia, Spain, 2Reina Sofia University Hospital, Cordoba, Andalucia, Spain, 3Reina Sofia University Hospital, Cordoba, Spain, 4Reina Sofia University Hospital, Córdoba, Spain

    Background/Purpose: Rheumatoid arthritis (RA) is a chronic inflammatory condition characterized by joint inflammation and systemic involvement. In this preliminary study, we explore the potential link…
  • Abstract Number: 0520 • ACR Convergence 2023

    How Do Early Disease Activity and Early Clinical Response Associate with Long-Term Outcomes with Ixekizumab in Radiographic Axial Spondyloarthritis?

    Sofia Ramiro1, Cedric Lukas2, Louis Bessette3, Pendleton Wickersham4, Soyi Liu-Leage5, Tommaso Panni5, Rebecca Bolce5, Boris Janos5, Michael Nissen6 and James Cheng-Chung Wei7, 1Department of Rheumatology, Leiden University Medical Center, Leiden, Netherlands, 2CHU Montpellier, Montpellier, France, 3Centre de l'Ostéoporose et de Rhumatologie de Québec, Quebec City, QC, Canada, 4Arthritis Associates PA, San Antonio, TX, 5Eli Lilly and Company, Indianapolis, IN, 6Geneva University Hospitals, Geneva, Switzerland, 7Chung Shan Medical University Hospital, Department of Rheumatology, Taichung, Taiwan

    Background/Purpose: The ASAS-EULAR recommendations for the management of axial spondyloarthritis (axSpA) advise that a patient be assessed for biological disease-modifying anti-rheumatic drug (bDMARD) treatment response…
  • Abstract Number: 0746 • ACR Convergence 2023

    The Association Between Sonographic Imaging Phenotype and Response to Treatment in Patients with Psoriatic Arthritis

    Jessica Gutierrez Manjarrez1, Sydney Thib2, Richard J. Cook3 and Lihi Eder4, 1Women’s College Research Institute / Department of Medicine, University of Toronto, Toronto, ON, Canada, 2Women’s College Research Institute, Toronto, ON, Canada, 3Department of Statistics and Actuarial Science, University of Waterloo, Waterloo, ON, Canada, 4Women’s College Research Institute, Division of Rheumatology, University of Toronto, Toronto, ON, Canada

    Background/Purpose: Ultrasound (US) may improve characterization of psoriatic arthritis (PsA) phenotypes and help predict disease outcomes. We aimed to assess whether US phenotypes are associated…
  • Abstract Number: 0840 • ACR Convergence 2023

    Head-to-Head Comparison of TLL-018 and Tofacitinib in Patients with Active Rheumatoid Arthritis: Final Results from a Phase IIa Study

    Xiaofeng Zeng1, chanyuan wu2, Jiankang Hu3, SHENGYUN LIU4, Zhenyu Jiang5, Jingyang Li6, Xiaoxia Wang7, Ju Liu8, Chaofan Yuan9, Guang Yang10 and Chris Liang10, 1Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China, 2Department of Rheumatology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China, 3Pingxiang People’s Hospital, PingXiang, China, 4The First Affiliated Hospital Of Zhengzhou University, Zhengzhou, China, 5The First Hospital of Jilin University, Changchun, China, 6Zhuzhou Central Hospital, Zhuzhou, China, 7Second Hospital of Shanxi Medical University, Taiyuan, China, 8Jiujiang No. 1 People’s Hospital, JiuJiang, China, 9Hangzhou Highlightll Pharmaceutical Co., Ltd, Beijing, China, 10Hangzhou Highlightll Pharmaceutical Co., Ltd, HangZhou, China

    Background/Purpose: None of the currently approved treatments for rheumatoid arthritis (RA) can achieve ACR50 in >50% of the patients, and 5 – 20% of the…
  • Abstract Number: 0974 • ACR Convergence 2023

    Validation of Boolean 2.0 Criteria for Assessing Remission and Predicting Quality of Life in Korean Patients with Rheumatoid Arthritis Undergoing Targeted Therapy

    Soo-Kyung Cho1, Yeo-Jin Song1, Jungyong Han2, Hye Won Kim3, Eunwoo Nam3 and Yoon-Kyoung Sung1, 1Hanyang University Hospital for Rheumatic Diseases, Seoul, South Korea, 2Hanyang University Hospital for Rheumatic Diseases, Seoul, South Korea, 3Hanyang University Institute for Rheumatology Research, Seoul, South Korea

    Background/Purpose: The management of rheumatoid arthritis (RA) focuses on achieving remission as a treatment goal. The updated ACR/EULAR remission definition (Boolean criteria 2.0) has raised…
  • Abstract Number: 1172 • ACR Convergence 2023

    Relapse Rate After Glucocorticoid-free Remission in Idiopathic Inflammatory Myopathies with Validation of the International Myositis Assessment & Clinical Studies Group (IMACS) Criteria for Remission and Relapse

    Hideaki Tsuji1, Fabricio Espinosa-Ortega2, Maryam Dastmalchi2, Ingrid Lundberg2 and Karin Lodin3, 1Division of Rheumatology, Department of Medicine, Karolinska Institutet; Department of Rheumatology and Clinical Immunology, Kyoto University Graduate School of Medicine, Kyoto, Japan, 2Division of Rheumatology, Department of Medicine, Karolinska Institutet; Department of Gastroenterology, Dermatotology, Rhematology, Karolinska Universitetssjukhuset, Stockholm, Sweden, 3Division of Rheumatology, Department of Medicine, Karolinska Institutet; Department of Gastroenterology, Dermatotology, Rhematology, Karolinska Universitetssjukhuset, Huddinge, Sweden

    Background/Purpose: Our aim was to explore whether maintenance of remission in patients with idiopathic inflammatory myopathy (IIM) depends on glucocorticoids (GCs) after achieving remission. Therefor…
  • Abstract Number: 1423 • ACR Convergence 2023

    Impact of Upadacitinib on Enthesitis and Dactylitis by Location in Patients with Psoriatic Arthritis and an Inadequate Response to Biologic DMARDs from the SELECT-PsA 2 Trial

    Laura Coates1, Catherine Bakewell2, Majed Khraishi3, Shirley Chen4, Tianming Gao4, Arathi Setty4, Heather Jones5, Sandra Ciecinski4 and Eduardo Mysler6, 1University of Oxford, Oxford, United Kingdom, 2Intermountain Healthcare Medical Group, Salt Lake City, UT, 3Memorial University of Newfoundland, St. John's, NL, Canada, 4AbbVie, Inc., North Chicago, IL, 5AbbVie, Inc., Mettawa, IL, 6Organización Medica de Investigación, Buenos Aires, Argentina

    Background/Purpose: Enthesitis and dactylitis are associated with reduced quality of life and greater impairment in daily activities. In the SELECT-PsA 2 phase 3 trial, the…
  • Abstract Number: 2143 • ACR Convergence 2023

    Efficacy of Filgotinib in Patients with Rheumatoid Arthritis: Week 156 Results from a Long-term Extension Study

    Maya Buch1, Daniel Aletaha2, Roberto F. Caporali3, Bernard G. Combe4, Hendrik Schulze-Koops5, Jacques-Eric Gottenberg6, Yoshiya Tanaka7, Ricardo Blanco8, Tsutomu Takeuchi9, Edmund V. Ekoka Omoruyi10, Katrien Van Beneden11, Vijay Rajendran12, Chris Watson13, Francesco De Leonardis14 and Paul Emery15, 1University of Manchester and NIHR Manchester Biomedical Research Centre, Manchester, United Kingdom, 2Division of Rheumatology, Department of Medicine III, Medical University of Vienna, Vienna, Austria, Wien, Austria, 3Department of Clinical Sciences and Community Health, University of Milan, and Department of Rheumatology and Medical Sciences, ASST Gaetano Pini-CTO, Milano, Italy, 4Department of Rheumatology, Montpellier University, Montpellier, France, 5Division of Rheumatology and Clinical Immunology, Department of Internal Medicine IV, Ludwig-Maximilians–University Munich, Munich, Germany, 6Rheumatology Department, Strasbourg University Hospital, Strasbourg, France, 7University of Occupational and Environmental Health, Kitakyushu, Japan, 8Hospital Universitario Marqués de Valdecilla, IDIVAL, Santander, Spain, 9Keio University School of Medicine and Saitama Medical University, Tokyo, Japan, 10Biostatistics, Galapagos NV, Mechelen, Belgium, 11Medical Safety, Galapagos NV, Mechelen, Belgium, 12Clinical Research, Galapagos NV, Mechelen, Belgium, 13Medical Affairs, Galapagos Biotech Ltd., Cambridge, United Kingdom, 14Medical Affairs, Galapagos GmbH, Basel, Switzerland, 15Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, and NIHR Leeds Biomedical Research Centre, Leeds Teaching Hospitals NHS Trust, Leeds, United Kingdom

    Background/Purpose: In the treatment of RA, JAK inhibitors are a valuable option to meet remission or low disease activity (LDA) treatment targets following an inadequate…
  • Abstract Number: 2334 • ACR Convergence 2023

    Remission Attainment in Patients with Systemic Lupus Erythematosus Treated with Anifrolumab Compared with Placebo over a 4-Year Period

    Ronald van Vollenhoven1, Eric Morand2, Richard A. Furie3, Kenneth Kalunian4, Raj Tummala5, Gabriel Abreu6, Hussein Al-Mossawi7 and Catharina Lindholm6, 1Amsterdam University Medical Centers, Amsterdam, Netherlands, 2Monash University, Centre for Inflammatory Diseases, Melbourne, Australia, 3Donald and Barbara Zucker School of Medicine at Hofstra/Northwell, Great Neck, NY, 4University of California San Diego, La Jolla, CA, 5BioPharmaceuticals R&D, AstraZeneca, Gaithersburg, MD, 6BioPharmaceuticals R&D, AstraZeneca, Gothenburg, Sweden, 7BioPharmaceuticals R&D, AstraZeneca, Cambridge, United Kingdom

    Background/Purpose: In patients with SLE, remission is an established therapeutic goal associated with reduced damage accrual and flares, and improved health-related quality of life.1 Here,…
  • Abstract Number: 2486 • ACR Convergence 2023

    Should SLE Patients Entering Clinical Trials Be Required to Have at Least One BILAG a And/or Two BILAG B Scores?

    Ewa Olech1 and Joan Merrill2, 1IQVIA, Rheumatology Consultants, PLLC, Las Vegas, NV, 2Oklahoma Medical Research Foundation, Oklahoma City, OK

    Background/Purpose: High placebo response rates have challenged interpretation of clinical trial results in SLE and may have contributed to failure of some effective treatments. One…
  • Abstract Number: 2551 • ACR Convergence 2023

    Remission and Low Disease Activity (LDA) in Patients with SLE Treated with Belimumab (BEL): Results from a Large Integrated Analysis

    Ioannis Parodis1, Julius Lindblom1, Roger A. Levy2, Margherita Zen3, Nursen Cetrez1, Alvaro Gomez4, Shereen Oon5, Christine Henning6, Munther Khamashta7, Holly A. Quasny8, Deven Chauhan9, Anca Askanase10, Ronald van Vollenhoven11 and Mandana Nikpour12, 1Karolinska Institutet, Stockholm, Sweden, 2GlaxoSmithKline, Global Medical Affairs, Collegeville, PA, 3University of Padua, Division of Rheumatology, Department of Medicine, Padua, Italy, 4Karolinska Institutet and Karolinska University Hospital, Division of Rheumatology, Department of Medicine Solna, Stockholm, Sweden, 5University of Melbourne at St Vincent’s Hospital, Departments of Rheumatology and Medicine, Fitzroy, Australia, 6GlaxoSmithKline, US Medical Affairs, Durham, NC, 7GSK Gulf, Medical Affairs Department, Dubai, United Arab Emirates, 8GlaxoSmithKline, Research & Development, Durham, NC, 9GlaxoSmithKline, Value Evidence and Outcomes, Brentford, United Kingdom, 10Columbia University Medical Center, New York, NY, 11Amsterdam Rheumatology and Immunology Center and Amsterdam University Medical Centers, Department of Rheumatology, Amsterdam, Netherlands, 12The University of Melbourne at St. Vincent’s Hospital Melbourne, Departments of Medicine and Rheumatology, Melbourne, Australia

    Background/Purpose: A key treatment goal in SLE management is the attainment of remission or LDA,1 for which various definitions exist, including “Definitions of Remission in…
  • Abstract Number: 0459 • ACR Convergence 2023

    Upadacitinib Monotherapy versus Methotrexate in Patients with Rheumatoid Arthritis: Efficacy and Safety Through 5 Years in the SELECT-EARLY Randomized Controlled Trial

    Ronald van Vollenhoven1, Vibeke Strand2, Tsutomu Takeuchi3, Nilmo Chávez4, Pablo Mannucci Walter5, Attul Singhal6, Jerzy Swierkot7, Nasser Khan8, Xianwei Bu9, Yihan Li9, Sara Penn9, Heidi Camp9 and Jacob Aelion10, 1Amsterdam University Medical Centers, Amsterdam, Netherlands, 2Stanford University, Portola Valley, CA, 3Keio University School of Medicine and Saitama Medical University, Tokyo, Japan, 4Instituto Guatemalteco de Seguridad Social, Guatemala, Guatemala, 5Aprillus Asistencia e Investigación, Buenos Aires, Argentina, 6Southwest Rheumatology Research Group, Dallas, TX, 7Department of Rheumatology and Internal Medicine, Wrocław Medical Hospital, Wrocław, Poland, 8Pharmacovigilance and Patient Safety, AbbVie, Inc., North Chicago, IL, 9AbbVie, Inc., North Chicago, IL, 10West Tennessee Research Institute, Jackson, TN

    Background/Purpose: To evaluate the efficacy and safety of upadacitinib (UPA) monotherapy vs MTX monotherapy over 5 yrs among MTX-naïve patients with moderately to severely active…
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All abstracts accepted to ACR Convergence are under media embargo once the ACR has notified presenters of their abstract’s acceptance. They may be presented at other meetings or published as manuscripts after this time but should not be discussed in non-scholarly venues or outlets. The following embargo policies are strictly enforced by the ACR.

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