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Abstracts tagged "regulatory cells and vasculitis"

  • Abstract Number: 25 • ACR/ARHP Annual Meeting 2018

    Circulating CD24hiCD38hi Regulatory B-Cells Influence Th17-Cell Responses in Patients with Granulomatosis with Polyangiitis

    Anouk von Borstel1, Lucas L. Lintermans2, P Heeringa3, Abraham Rutgers2, Coen A. Stegeman1, Jan-Stephan F. Sanders1 and Wayel H. Abdulahad2, 1Internal Medicine, Division of Nephrology, University of Groningen, University Medical Center Groningen, Groningen, Netherlands, 2Rheumatology and Clinical Immunology, University of Groningen, University Medical Center Groningen, Groningen, Netherlands, 3Pathology and Medical Biology, University of Groningen, University Medical Center Groningen, Groningen, Netherlands

    Background/Purpose: To investigate whether there is a direct relation between expanded proportions of Th17-effector memory (ThEM17) cells and diminished proportions of regulatory B-cells (Bregs) in…

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