regulatory cells and transcription factor Archives

Abstract Number: 2722 • ACR/ARHP Annual Meeting 2014
Rapamycin Corrects GATA-3 Deficiency in Lupus Treg
Hiroshi Kato¹ and Andras Perl², ¹Internal Medicine, Division of Rheumatology, SUNY Upstate Medical University, Syracuse, NY, ²Dept of Medicine, SUNY Upstate Medical University, Syracuse, NY
Background/Purpose: As demonstrated by the negative correlation between Treg frequency or suppressive function and SLE disease activity index score, it is tempting to speculate that…
Abstract Number: 2352 • ACR/ARHP Annual Meeting 2014
RORγt Expressing Foxp3⁺ Regulatory T Cells Regulates the Development of Autoimmune Arthritis in Mice
Yuya Kondo¹, Masahiro Tahara¹, Mana Iizuka¹, Masahiro Yokosawa¹, Shunta Kaneko¹, Hiroto Tsuboi¹, Satoru Takahashi², Isao Matsumoto³ and Takayuki Sumida¹, ¹Department of Internal Medicine, Faculty of Medicine, University of Tsukuba, Tsukuba, Japan, ²Laboratory Animal Resource Center, University of Tsukuba, Tsukuba, Japan, ³Department of Interenal Medicine, Faculty of Medicine, University of Tsukuba, Tsukuba, Japan
Background/Purpose: To determine the effect of RORγt overexpression in T cells on the development of collagen induced arthritis (CIA). Methods: Arthritis was induced with chicken…
Abstract Number: 2315 • ACR/ARHP Annual Meeting 2012
Foxp3⁺ Treg Cells Decreased in Overexpression of T-Bet in PD-1 Deficient Mice
Masahiro Tahara¹, Yuya Kondo¹, Hiroto Tsuboi², Satoru Takahashi³, Isao Matsumoto¹ and Takayuki Sumida¹, ¹Department of Internal Medicine, Faculty of Medicine, University of Tsukuba, Tsukuba, Ibaraki, Japan, ²Department of Internal Medicine, Faculty of Medicine, University of Tsukuba, Tsukuba, Japan, ³Department of Anatomy and Embryology, Faculty of Medicine, University of Tsukuba, Tsukuba city, Ibaraki, Japan
Background/Purpose: Programmed cell Death-1 (PD-1) plays an important role in peripheral T cell tolerance, therefore PD-1 deficient (PD-1 KO) mice develop strain-specific autoimmune phenotypes. C57BL/6…

Abstracts tagged "regulatory cells and transcription factor"

Rapamycin Corrects GATA-3 Deficiency in Lupus Treg

RORγt Expressing Foxp3+ Regulatory T Cells Regulates the Development of Autoimmune Arthritis in Mice

Foxp3+ Treg Cells Decreased in Overexpression of T-Bet in PD-1 Deficient Mice

RORγt Expressing Foxp3⁺ Regulatory T Cells Regulates the Development of Autoimmune Arthritis in Mice

Foxp3⁺ Treg Cells Decreased in Overexpression of T-Bet in PD-1 Deficient Mice