Abstracts tagged "regulatory cells and spondylarthropathy"

Abstract Number: 600 • 2012 ACR/ARHP Annual Meeting
Regulatory T Cells in Spondyloarthritis (SpA) Animal Model and Modulatory Role of Inducible Costimulator (ICOS)
Luiza Krause¹, Ingrid Fert¹, Karine Labroquère², Muriel Andrieu², Gilles Chiocchia³ and Maxime A. Breban⁴, ¹Immunology and Hematology Department, Institut Cochin - INSERM U1016 - CNRS (UMR 8104)-Université Paris Descartes (UMR-S 1016), Paris, France, ²Cochin Immunobiology Facility, Paris, France, ³Versailles Saint Quentin en Yvelines University, INSERM U987, UFR des Sciences de la Santé, Montigny-le-Bretonneux, France, ⁴Rheumatology Division, Ambroise Paré Hospital (AP-HP), and Versailles Saint Quentin en Yvelines University, Boulogne-Billancourt, France
Background/Purpose: HLA-B27/human β2m transgenic rats (B27-rats), a model of SpA develop spontaneous colitis and arthritis. It was recently shown in this model that IL-17 producing…