ACR Meeting Abstracts

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Abstracts tagged "regulatory cells and rheumatoid arthritis"

  • Abstract Number: 152 • 2018 ACR/ARHP Annual Meeting

    Polymorphonuclear Neutrophils and Regulatory T Lymphocytes (Treg) Cooperate to Sustain Treg Activity in Normal and Arthritic Contexts

    Maxime Batignes1, François Santinon1, Marie-Christophe Boissier2,3, Patrice Decker4 and Natacha Bessis1, 1INSERM UMR 1125 University of Paris 13, Sorbonne Paris Cité, Bobigny, France, 2University of Paris 13,Sorbonne Paris Cité, Bobigny, France, 3Rheumatology Department, Assistance Publique – Hôpitaux de Paris (AP-HP), Avicenne Hospital, Bobigny, France, 4Inserm UMR 1125, Li2P, University of Paris 13, Sorbonne Paris Cité, Bobigny, France

    Background/Purpose: Polymorphonuclear neutrophils (PMN) are abundant and activated in rheumatoid arthritis (RA) joints. In addition to their pro-inflammatory role, PMN exert immunoregulatory functions and may…
  • Abstract Number: 2563 • 2015 ACR/ARHP Annual Meeting

    Immune Regulation By Migrating Mesenchymal Stem Cells Ameliorate Inflammatory Arthritis in Mice

    Seung Min Jung, Yoojun Nam and Ji Hyeon Ju, Division of Rheumatology, Department of Internal Medicine, College of Medicine, The Catholic University of Korea, Seoul, South Korea

    Background/Purpose: Mesenchymal stem cells (MSCs) function as immune regulators in inflammatory conditions. However, it is unclear how to control local inflammation by systemically administered MSCs. We…
  • Abstract Number: 998 • 2014 ACR/ARHP Annual Meeting

    β2 Adrenoceptor Signal Is Augmented in B Cells in the Course of Arthritis to Increase IL-10

    Georg Pongratz1, Clemens Wiest2, Madlen Melzer2 and Rainer Straub3, 1Internal Medicine I, University Hospital Regensburg, Regensburg, Germany, 2University Hospital Regensburg, Regensburg, Germany, 3Internal Medicine, University Hospital Regensburg, Regensburg, Germany

    Background/Purpose Splenic B cells from collagen-induced arthritis (CIA) mice react to a β2-adrenoceptor (AR) stimulus with increased IL-10 production and adoptive transfer of these cells…
  • Abstract Number: 449 • 2014 ACR/ARHP Annual Meeting

    Citrullinated-Vimentin-Specific Regulatory T-Cell Responses Associate with ACPA Positive Individuals with Non-Specific Musculoskeletal Symptoms

    Aamir Aslam1, Jackie L. Nam1, Laura Hunt1, Chadi Rakieh1, Ann W. Morgan2 and Paul Emery1, 1NIHR-Leeds Musculoskeletal Biomedical Research Unit and Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, Leeds, United Kingdom, 2NIHR-Leeds Musculoskeletal Biomedical Research Unit, University of Leeds, Leeds, United Kingdom

    Background/Purpose: The pathogenesis of RA can be conceptualised by sequential phases that precede the development of synovitis.  Autoimmune antibody responses, including ACPA, can precede clinical…
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ACR Convergence: Where Rheumatology Meets. All Virtual. November 5-9.

ACR Pediatric Rheumatology Symposium 2020

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