Abstracts tagged "registries"

Abstract Number: 2936 • 2014 ACR/ARHP Annual Meeting
Is Ankylosing Spondylitis a Risk Factor for Cardiovascular Diseases, and How Does These Risks Compare to Those in Rheumatoid Arthritis?
Johan Askling¹, Lennart Jacobsson² and Jonas Eriksson¹, ¹Clinical Epidemiology Unit, Department of Medicine, Karolinska Institutet, Stockholm, Sweden, ²sahlrenska academy, gothenburg, Sweden
Background/Purpose Patients with RA are at increased risk of cardiovascular (CV) diseases, including acute coronary syndromes (ACS), deep venous thromboembolism (DVT) and pulmonary embolism (PE),…
Abstract Number: 1027 • 2013 ACR/ARHP Annual Meeting
Factors Associated With Decisions To Adjust Therapy For Rheumatoid Arthritis Patients In Moderate To High Disease Activity
Yomei Shaw¹, Chung-Chou H. Chang^2,3, Heather Eng⁴, Ilinca D. Metes⁵, Stephen R. Wisniewski⁶, Mark S. Roberts¹ and Marc C. Levesque⁷, ¹Department of Health Policy and Management, University of Pittsburgh Graduate School of Public Health, Pittsburgh, PA, ²Department of Medicine, University of Pittsburgh Department of Medicine, Pittsburgh, PA, ³Department of Medicine, University of Pittsburgh, Pittsburgh, PA, ⁴Epidemiology Data Center, University of Pittsburgh, Graduate School of Public Health, Pittsburgh, PA, ⁵Department of Medicine, Division of Clinical Immunology and Rheumatology, University of Pittsburgh, Pittsburgh, PA, ⁶Epidemiology, University of Pittsburgh, Graduate School of Public Health, Pittsburgh, PA, ⁷Division of Rheumatology and Clinical Immunology, University of Pittsburgh, Pittsburgh, PA
Background/Purpose: The American College of Rheumatology (ACR) recommends treating rheumatoid arthritis (RA) to the target of low disease activity or remission with traditional and biologic…
Abstract Number: 803 • 2013 ACR/ARHP Annual Meeting
The Risk Of Serious Infections In Patients Receiving Rituximab For Rheumatoid Arthritis: Results From The British Society For Rheumatology Biologics Register-Rheumatoid Arthritis
Lucía Silva-Fernández^1,2, Mark Lunt³, Audrey S. Low², Kath D. Watson³, BSRBR Control Centre Consortium², Deborah P. Symmons², Kimme L. Hyrich⁴ and On behalf of the BSRBR⁵, ¹Rheumatology, Hospital Universitario de Guadalajara, Guadalajara, Spain, ²Arthritis Research UK Epidemiology Unit, University of Manchester, Manchester, United Kingdom, ³Arthritis Research UK Centre for Epidemiology, University of Manchester, Manchester, United Kingdom, ⁴Arthritis Research UK Epidemiology Unit, Manchester Academic Health Sciences Centre, Institute of Inflammation and Repair, The University of Manchester, Manchester, United Kingdom, ⁵British Society for Rheumatology, London, United Kingdom
Background/Purpose: In the United Kingdom (UK), rituximab (RTX), an anti-CD20 monoclonal antibody, is currently used to treat patients with rheumatoid arthritis (RA) who have failed…
Abstract Number: 448 • 2013 ACR/ARHP Annual Meeting
Effectiveness Of Tocilizumab In Monotherapy and In Combination With Different Synthetic Dmards: A Registry-Based Comparison Study
Cem Gabay¹, Myriam Riek², Merete Lund Hetland³, Ulrik Tarp⁴, K. Pavelka⁵, Matija Tomsic⁶, Helena Canhao⁷, Katerina Chatzidionysiou⁸, R.F. van Vollenhoven⁹, Galina Lukina¹⁰, E. Nasonov¹¹, Dan C. Nordström¹², Elisabeth Lie¹³, Ioan Ancuta¹⁴, Estibaliz Loza Santamaria¹⁵, Piet Van Riel¹⁶ and Tore K. Kvien¹³, ¹Rheumatology, Geneva University Hospitals, Geneva, Switzerland, ²SCQM Registry, Zurich, Switzerland, ³DANBIO, Center for Rheumatology and Spine Diseases, Glostrup Univ Hospital, Glostrup, Denmark, ⁴Department of Rheumatology, Aarhus University Hospital, Aarhus, Denmark, ⁵Department of Clinical and Experimental Rheumatology, Charles University, Prague, Czech Republic, ⁶Department of Rheumatology, University Medical Centre Ljubjana, Ljubljana, Slovenia, ⁷Rheumatology Research Unit, Rheumatology Research Unit, on behalf of the Rheumatic Diseases Portuguese Register, Instituto de Medicina Molecular, Rheumatology Research Unit, Rheumatology Research Unit, on behalf of the Rheumatic Diseases Portuguese Register, Lisbon, Portugal, ⁸Dept of Medicine, Unit for Clinical Research Therapy. Inflammatory Diseases (ClinTrid), Karolinska Institute, Stockholm, Sweden, ⁹Karolinska Institute, Stockholm, Sweden, ¹⁰ARBITER, Institute of Rheumatology, Moscow, Russia, ¹¹Institute of Rheumatology, Moscow, Russia, ¹²ROB-FIN, Helsinki University Central Hospital, Helsinki, Finland, ¹³Dept. of Rheumatology, Diakonhjemmet Hospital, Oslo, Norway, ¹⁴“Dr. I. Cantacuzino” Hospital, Bucharest, Romania, ¹⁵Instituto de salud Musculoesqueletica, Madrid, Spain, ¹⁶Radboud University Nijmegen Medical Centre, Nijmegen, Netherlands
Background/Purpose: Tocilizumab (TCZ) is efficacious in monotherapy and in combination with methotrexate (MTX) or other DMARDs. However, longitudinal data from large registry populations are missing.…
Abstract Number: 2362 • 2013 ACR/ARHP Annual Meeting
Incidence Of Adverse Events In Patients With Rheumatoid Arthritis and Spondyloarthritis Exposed To Anti-TNF Therapy. Data From The Brazilian Registry For Monitoring Of Biologic Therapies In Rheumatic Diseases (BiobadaBrasil)
Roberto Ranza¹, David C Titton², Valeria Vallim³, Ines Silveira⁴, Aline Ranzolin⁵, Andre Hayata⁶, Mirhelen M. Abreu⁷, Paulo Louzada-Jr⁸, Angela LBP Duarte⁵, Claiton Brenol⁹, Geraldo C Pinheiro¹⁰, Glaucio R Castro¹¹, Hellen M Carvalho¹², Isaias Costa¹³, Jose C Macieira¹⁴, Jose R Miranda¹⁵, Julio CM Bertacini¹⁶, Luis SG Barbosa¹⁷, Manoel B Bertolo¹⁸, Marcelo M. Pinheiro¹², Maria F Sauma¹⁹, Marilia B Silva²⁰, Marlene Freire²¹, Roberto A Toledo²² and Vander Fernandes²³, ¹Universidade Federal de Uberlandia, Uberlandia MG, Brazil, ²Hospital de Clínicas da UFPR, Curitiba PR, Brazil, ³Universidade Federal do Espirito Santo, Vitoria ES, Brazil, ⁴PUCRS, Porto Alegre RS, Brazil, ⁵Universidade Federal de Pernambuco, Recife PE, Brazil, ⁶CRO Osasco, Osasco SP, Brazil, ⁷Universidade Federal de São Carlos, São Carlos SP, Brazil, ⁸USP RP, Ribeirão Preto SP, Brazil, ⁹Universidade Federal do Rio Grande do Sul, Porto Alegre RS, Brazil, ¹⁰UERJ, Rio de Janeiro RJ, Brazil, ¹¹Hospital Governador Celso Ramos, Florianopolis SC, Brazil, ¹²Brazilian Registry of Spondyloarthritis, São Paulo, Brazil, ¹³Universidade Federal MS, Campo Grande MS, Brazil, ¹⁴UFS Aracaju, Aracaju SE, Brazil, ¹⁵Artrocenter Clinica Medica, Taubate SP, Brazil, ¹⁶USP SP CDMAC, São Paulo SP, Brazil, ¹⁷Universidade Federal Mato Grosso, Cuiabá MT, Brazil, ¹⁸UNICAMP, Campinas SP, Brazil, ¹⁹UFPA, Belem PA, Brazil, ²⁰Hospital Universitario Evangelico, Curitiba PR, Brazil, ²¹UFTM, Uberaba MG, Brazil, ²²FUNFARP, São José do Rio Preto SP, Brazil, ²³Universidade de Cuiabá, Cuiaba MT, Brazil
Background/Purpose: The safety profile of a-TNF biologic drugs might have substantial regional differences due to geographic and socio economic factors and to epidemiology of infectious…
Abstract Number: 2345 • 2013 ACR/ARHP Annual Meeting
Long-Term Targeted Safety Event Rates In RA Patients Following Initiation Of Rituximab: Interim Analysis From Sunstone Registry
Kenneth G. Saag¹, Kevin L. Winthrop², Kimberly Alexander³, Steven Francom⁴ and Daniel Furst⁵, ¹Immunology & Rheumatology, The University of Alabama at Birmingham, Birmingham, AL, ²Dept of Infectious Disease, Oregon Health & Science University, Portland, OR, ³Epidemiology, Genentech, Inc., South San Francisco, CA, ⁴Genentech, Inc., South San Francisco, CA, ⁵Rheumatology, UCLA, Los Angeles, CA
Background/Purpose: Rituximab (RTX) is used for the treatment of rheumatoid arthritis (RA) in patients (pts) with an inadequate response to anti-TNF therapy (TNF-IR). Long-term safety…
Abstract Number: 2117 • 2013 ACR/ARHP Annual Meeting
The Effect Of Statin Therapy On Venous Thromboembolism After Hip Or Knee Arthroplasty
Anne R. Bass¹, Yuo-Yu Lee², Stephen Lyman³, Geoffrey H. Westrich⁴ and Brian F. Gage⁵, ¹Rheumatology, Hospital for Special Surgery Weill Cornell Medical College, New York, NY, ²Hospital for Special Surgery, New York, NY, ³Research, Hospital for Special Surgery, New York, NY, ⁴Orthopedics, Hospital for Special Surgery, New York, NY, ⁵Medicine, Washington University School of Medicine in St. Louis, St. Louis, MO
Background/Purpose: Patients undergoing hip and knee arthroplasty are at high risk of venous thromboembolism (VTE). HMG Co-A reductases (“statins”) can reduce the risk of post-operative…
Abstract Number: 1438 • 2013 ACR/ARHP Annual Meeting
Comparative Effectiveness Of Rituximab Vs. Subsequent Anti-Tumor Necrosis Factor In Patients With Rheumatoid Arthritis With Prior Exposure To TNFi
Leslie R. Harrold¹, George W. Reed², Robert P. Magner¹, Ashwini Shewade³, Ani John³, Jeffrey D. Greenberg⁴ and Joel M. Kremer⁵, ¹University of Massachusetts Medical School, Worcester, MA, ²CORRONA, Inc., Southborough, MA, ³Genentech Inc., South San Francisco, CA, ⁴NYU Hospital for Joint Diseases, New York, NY, ⁵Albany Medical College and The Center for Rheumatology, Albany, NY
Background/Purpose: In patients (pts) who have failed 1 or more TNF-α inhibitors (TNFi), there is little data to guide clinical decision making in terms of…

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