Abstracts tagged "reactive arthritis and metabolomics"

Abstract Number: 634 • 2019 ACR/ARP Annual Meeting
Targeted 1H NMR Based Metabolomics Analysis Revealed Significantly Higher Synovial Phe/Tyr Ratio in Reactive Arthritis and Undifferentiated Spondyloarthropathy
Hafis Muhammed¹, Dinesh Kumar ², Durgesh Dubey ², Sandeep Kumar ³, Smriti Chaurasia ³, Anupam Guleria ², Sanjukta Majumder ³, Rajeev Singh ³, Vikas Agarwal ¹ and Ramnath Misra ⁴, ¹SGPGI, Lucknow, Uttar Pradesh, India, ²Centre for Biomedical Research, Sanjay Gandhi Post Graduate Institute of Medical Science, Lucknow, Uttar Pradesh, India, ³Department of Clinical Immunology and Rheumatology, Sanjay Gandhi Post Graduate Institute of Medical Science, Lucknow, Uttar Pradesh, India, ⁴Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, Lucknow, Uttar Pradesh, India
Background/Purpose: Elevated phenylalanine-to-tyrosine ratio (Phe/Tyr) is a marker of oxidative stress. We hypothesized that the synovial Phe/Tyr in reactive arthritis is higher than Rheumatoid arthritis(RA)…

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