ACR Meeting Abstracts

ACR Meeting Abstracts

  • Meetings
    • ACR Convergence 2024
    • ACR Convergence 2023
    • 2023 ACR/ARP PRSYM
    • ACR Convergence 2022
    • ACR Convergence 2021
    • ACR Convergence 2020
    • 2020 ACR/ARP PRSYM
    • 2019 ACR/ARP Annual Meeting
    • 2018-2009 Meetings
    • Download Abstracts
  • Keyword Index
  • Advanced Search
  • Your Favorites
    • Favorites
    • Login
    • View and print all favorites
    • Clear all your favorites
  • ACR Meetings

Abstracts tagged "Randomized Trial"

  • Abstract Number: 0593 • ACR Convergence 2024

    Value of the Routine Assessment of Patient Index Data 3 in Assessing Disease Severity and Treatment Effect in Patients with Early Oligoarticular Psoriatic Arthritis Treated with Apremilast

    Alvin F. Wells1, Arthur Kavanaugh2, William Tillett3, Philip S. Helliwell4, Marijn Vis5, Yuri Klyachkin6, Cynthia Deignan7, Lichen Teng7, Rebecca Wang7 and Alexis Ogdie8, 1Rheumatology and Immunotherapy Center, Franklin, WI, 2University of California San Diego, La Jolla, CA, 3Royal National Hospital of Rheumatic Diseases; Department of Life Sciences, Centre for Therapeutic Innovation, University of Bath, Bath, United Kingdom, 4Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, Leeds, UK, Leeds, United Kingdom, 5Erasmus MC, Rotterdam, Netherlands, 6Amgen, Lexington, KY, 7Amgen Inc., Thousand Oaks, CA, 8Department of Medicine, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA

    Background/Purpose: The Routine Assessment of Patient Index Data 3 (RAPID3) score is a composite of 3 patient-reported outcomes (PROs): Health Assessment Questionnaire (HAQ), pain visual…
  • Abstract Number: 1465 • ACR Convergence 2024

    The Use of Disease Activity Thresholds for the Psoriatic Arthritis Impact of Disease Questionnaire to Assess Patient Perceptions of Disease Burden in Patients with Early Oligoarticular Psoriatic Arthritis Treated with Apremilast in a Phase 4 Trial

    Laure Gossec1, Laura Coates2, Dafna Gladman3, Alexis Ogdie4, Peter Nash5, Denis Poddubnyy6, Arthur Kavanaugh7, April Armstrong8, Carlo Selmi9, Ruben Queiro Silva10, Cynthia Deignan11, Rebecca Wang11, Jyotsna Reddy11, Michele Brunori11 and Philip Mease12, 1Sorbonne Université, Paris, France, 2University of Oxford, Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, Oxford, United Kingdom, 3University of Toronto, Toronto Western Hospital, Toronto, ON, Canada, 4Department of Medicine, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, 5School of Medicine, Griffith University, Sunshine Coast, Queensland, Australia, 6Charite-Universitatsmedizin Berlin, Berlin, Germany, 7University of California, San Diego, School of Medicine, La Jolla, CA, 8University of California Los Angeles, Los Angeles, CA, 9Department of Biomedical Sciences, Humanitas University, Rozzano, Italy, 10Rheumatology Division, Hospital Universitario Central de Asturias, Oviedo University School of Medicine, Oviedo, Spain, 11Amgen Inc., Thousand Oaks, CA, 12Swedish Medical Center/Providence St. Joseph Health; University of Washington School of Medicine, Seattle, WA

    Background/Purpose: Oligoarticular psoriatic arthritis (PsA, ≤4 joints affected) is common but understudied, as most clinical trials enroll patients (pts) with ≥3 swollen and tender joints.…
  • Abstract Number: 1676 • ACR Convergence 2024

    Changing Patients’ Mindsets About Non-Severe Side Effects of Methotrexate: A Randomized Controlled Trial

    Rachael Yielder1, Kari Leibowitz2, Alia Crum2, Paul Manley3, Nicola Dalbeth1 and Keith Petrie4, 1University of Auckland, Auckland, New Zealand, 2Stanford University, Palo Alto, CA, 3Te Whatu Ora Health New Zealand, Auckland, New Zealand, 4The University of Auckland, Auckland, New Zealand

    Background/Purpose: Although methotrexate (MTX) is a first-line treatment for inflammatory rheumatic diseases, side effects can lead to poor adherence and persistence. A novel intervention involves…
  • Abstract Number: 2185 • ACR Convergence 2024

    TRACER: Transition to Adulthood Through Coaching and Empowerment in Rheumatology, a Feasibility Study

    Megan Clarke1, Julie Herrington2, Tania Cellucci3, Liane Heale4, Mark Matsos5, KAREN BEATTIE2, Roberta A Berard6 and Michelle Batthish3, 1McMaster Universitys, Hamilton, Canada, 2McMaster University, Hamilton, ON, Canada, 3McMaster Children's Hospital, Hamilton, ON, Canada, 4McMaster University, Oakville, ON, Canada, 5McMaster Lupus Clinic, Division of Rheumatology, Department of Medicine, McMaster University, Hamilton, ON, Canada, 6London Health Sciences Centre, London, ON, Canada

    Background/Purpose: The transition from pediatric to adult healthcare is a vulnerable time for youth with chronic disease, with risks of disengagement from care and subsequent…
  • Abstract Number: 2431 • ACR Convergence 2024

    DORIS Remission in Patients with SLE Treated with Anifrolumab: Post Hoc Analysis from TULIP-1 and TULIP-2 Trials in Patents with No Reported History of Prior Immunosuppressant Use

    doria Andrea1, Ronald Van Vollenhoven2, Eric Morand3, Catharina Lindholm4, Jonatan Hedberg4, Miina Waratani5 and Danuta Kielar6, 1University of Padova, Padova, Italy, 2Department of Rheumatology and Clinical Immunology, Amsterdam University Medical Centers, Amsterdam, Netherlands, 3School of Clinical Sciences, Monash University, Melbourne, Victoria, Australia, 4BioPharmaceuticals Medical, AstraZeneca, Gothenburg, Sweden, 5Biopharmaceuticals Medical, AstraZeneca, Cambridge, United Kingdom, 6Biopharmaceuticals Medicine, AstraZeneca, Cambridge, United Kingdom

    Background/Purpose: 2023 EULAR recommendations for the management of SLE open up the option for early treatment initiation with biologics without the requirement to fail immunosuppressants/DMARDs…
  • Abstract Number: 0620 • ACR Convergence 2024

    Clinical Efficacy and Patient-Reported Outcomes in Anti-Ro/Sjögren’s Syndrome–Related Antigen a Antibody–Positive Patients with Active SLE Treated WithDeucravacitinib in the Phase 2 PAISLEY Trial

    Benjamin A. Fisher1, Hendrika Bootsma2, Vibeke Strand3, Wan-Fai Ng4, Thomas Wegman5, Brandon Becker6, Jiyoon Choi6, Antoine Sreih6, Leo Chen7, Antonia Christodoulou6 and Eric Morand8, 1University of Birmingham, Birmingham, United Kingdom, 2Department of Rheumatology and Clinical Immunology, University of Groningen, University Medical Center Groningen, Groningen, Groningen, Netherlands, 3Division of Immunology/Rheumatology, Stanford University, Palo Alto, CA, 4Institute of Cellular Medicine, Newcastle University, Gateshead, United Kingdom, 5Bristol Myers Squibb, Beaver Falls, PA, 6Bristol Myers Squibb, Princeton, NJ, 7Bristol Myers Squibb, Richmond, BC, Canada, 8School of Clinical Sciences, Monash University, Melbourne, Victoria, Australia

    Background/Purpose: Deucravacitinib is a first-in-class, oral, selective, allosteric tyrosine kinase 2 (TYK2) inhibitor approved in multiple countries for the treatment of adults with moderate to…
  • Abstract Number: 1466 • ACR Convergence 2024

    Apremilast Treatment in Early Oligoarticular Psoriatic Arthritis Improves Clinical and Patient-Reported Outcomes for up to 48 Weeks – Data from a Phase 4 Trial

    Laure Gossec1, Laura Coates2, Dafna Gladman3, Alexis Ogdie4, Alvin F. Wells5, Joseph Merola6, Paolo Gisondi7, andreas pinter8, Mitsumasa Kishimoto9, Jyotsna Reddy10, Hamid Amouzadeh10, Rebecca Wang10, Shauna Jardon10, Michele Brunori10 and Philip Mease11, 1Sorbonne Université, Paris, France, 2University of Oxford, Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, Oxford, United Kingdom, 3University of Toronto, Toronto Western Hospital, Toronto, ON, Canada, 4Department of Medicine, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, 5Rheumatology and Immunotherapy Center, Franklin, WI, 6UT Southwestern Medical Center, Newton, MA, 7Dermatology and Venereology, Department of Medicine, Università di Verona, Verona, Italy, 8University Hospital of the Goethe University, Frankfurt am Main, Frankfurt, Germany, 9Department of Nephrology and Rheumatology, Kyorin University School of Medicine, Tokyo, Japan, 10Amgen Inc., Thousand Oaks, CA, 11Swedish Medical Center/Providence St. Joseph Health; University of Washington School of Medicine, Seattle, WA

    Background/Purpose: Most clinical trials of Psoriatic Arthritis (PsA) exclude patients with early oligoarticular (oligo) disease and there is limited evidence to drive treatment decisions in…
  • Abstract Number: 1678 • ACR Convergence 2024

    Efficacy, Safety, Pharmacokinetics of Anti-CD40 Antibody Abiprubart in Patients with Rheumatoid Arthritis: A Phase 2, Randomized, Placebo-Controlled 12-week-treatment Proof-of-Concept Study

    Eric Jenkins1, Ingrid Louw2, Attila Balog3, Elsa van Duuren4, diane Horowitz5, Janusz Jaworski6, Alan Kivitz7, Ilona Kemplerne Ujfalussy8, Joe Pirrello1, Eben Tessari1, Sheldon Wang1 and John F Paolini1, and KPL-404-C211 Investigators, 1Kiniksa Pharmaceuticals, Lexington, MA, 2Panorama Medical Centre, Cape Town, South Africa, 3Albert Szent-Györgyi Medical School, University of Szeged, Szeged, Hungary, 4The Sefako Makgatho Health Science University, Pretoria, South Africa, 5Feinstein Institute for Medical Research, New York, NY, 6Reumatika-Centrum Reumatologii, Warszawa, Poland, 7Altoona Center for Clinical Research, Duncansville, PA, 8Medical Centre, Hungarian Defense Forces, Dózsa György út 112, Budapest, Hungary

    Background/Purpose: Rheumatoid arthritis (RA) patients (pts) with inadequate response or intolerance to current biologic/targeted synthetic disease-modifying anti-rheumatic drugs (b/tsDMARDs) have limited options. Abiprubart, a humanized…
  • Abstract Number: 2269 • ACR Convergence 2024

    Adalimumab Dose Reduction Using Therapeutic Drug Monitoring to Manage Low Disease Activity in Rheumatoid Arthritis: A Single-Blind, Non-Inferiority, Randomized Clinical Trial

    Sadaf Atiqi1, Maike Wientjes2, Maureen Leeuw3, Laura Boekel4, Femke Hooijberg1, Floris Loeff5, Charlotte Krieckaert1, Annick De Vries5, Michael Nurmohamed6, Theo Rispens5, Maarten Boers7, Bart van den Bemt8, Alfons den Broeder2 and Gertjan Wolbink9, 1Reade, Amsterdam, Netherlands, 2Sint Maartenskliniek, Ubbergen, Netherlands, 3Reade, Zeist, Netherlands, 4Vrije Universiteit Amsterdam, Amsterdam, Netherlands, 5Sanquin Diagnostic Services, Amsterdam, Netherlands, 6Reade and Amsterdam UMC, Kortenhoef, Netherlands, 7Amsterdam UMC, Vrije Universiteit, Amersfoort, Netherlands, 8Sint Maartenskliniek / Radboudumc, Ubbergen, Netherlands, 9Reade and Sanquin Diagnostic Services, Amsterdam, Netherlands

    Background/Purpose: The latest European and American recommendations support tapering of biological DMARDs (bDMARDs) in patients with persistent remission or low disease activity. Most clinicians use…
  • Abstract Number: 2563 • ACR Convergence 2024

    Efficacy and Safety Results of CT-P41 (Proposed Denosumab Biosimilar) Compared to Reference Denosumab in Postmenopausal Women with Osteoporosis: 78-Week Results from Phase 3 Randomized Controlled Trial

    Jean-Yves Reginster1, Stuart L. Silverman2, Edward Czerwinski3, Przemyslaw Borowy4, Tomasz Budlewski5, Joanna Kwiatek6, Svitlana Postol7, Airi Põder8, Jerzy Supronik9, SungHyun Kim10, JeeHye Suh10, GoEun Yang10, NooRi Han10, NaHyun Kim10 and SeoHee Bae10, 1Biochemistry Dept, College of Science, King Saud University, Riyadh, Kingdom of Saudi Arabia, CLARENS, Switzerland, 2OMC clinical research center and Cedars Sinai Medical Center, Beverly Hills, CA, 3Krakow Medical Centre, Kraków, Poland, 4Krakowskie Centrum Medyczne, Krakow, Poland, 5Department of Rheumatology, Medical University of Lodz, Lodz, Poland, 6Centrum Medyczne Poznan - PRATIA, Skorzewo, Poland, 7Medical Center of Medbud - Clinic LLC, Kyiv, Ukraine, 8Clinical Research Centre Ltd, Tartu, Estonia, 9Osteo-Medic s.c., Białystok, Poland, 10Celltrion, Inc., Incheon, Republic of Korea

    Background/Purpose: CT-P41 is a proposed biosimilar of the reference denosumab (DEN), a fully human monoclonal antibody that binds the cytokine receptor activator of NF-κb ligand…
  • Abstract Number: 0662 • ACR Convergence 2024

    Deucravacitinib, a First-in-Class, Oral, Selective, Allosteric Tyrosine Kinase 2 Inhibitor, in SLE: Efficacy by Baseline Demographics and Disease Characteristics in the Phase 2 PAISLEY Trial

    Eric Morand1, Cristina Arriens2, Laura Geraldino3, Ann E. Clarke4, Samantha Pomponi5, Coburn Hobar5, Thomas Wegman6, Ravi Koti5, Subhashis Banerjee5 and Ronald Van Vollenhoven7, 1School of Clinical Sciences, Monash University, Melbourne, Victoria, Australia, 2Department of Arthritis and Clinical Immunology, Rheumatology, Oklahoma Medical Research Foundation and Department of Medicine, University of Oklahoma Health Sciences Center, Oklahoma City, OK, 3Division of Rheumatology, Department of Medicine, Columbia University, New York, NY, 4Division of Rheumatology, Cumming School of Medicine, University of Calgary, Calgary, AB, Canada, 5Bristol Myers Squibb, Princeton, NJ, 6Bristol Myers Squibb, Beaver Falls, PA, 7Department of Rheumatology and Clinical Immunology, Amsterdam University Medical Centers, Amsterdam, Netherlands

    Background/Purpose: Deucravacitinib is a first-in-class, oral, selective, allosteric tyrosine kinase (TYK2) inhibitor approved in multiple countries for the treatment of adults with moderate to severe…
  • Abstract Number: 1472 • ACR Convergence 2024

    Achievement of Low Disease Activity/Remission in Guselkumab-Treated Patients with Moderately-Highly Active Psoriatic Arthritis Regardless of Baseline Characteristics: Pooled Post-Hoc Analysis of Two Phase 3/Randomized Studies

    Philip Mease1, Alice Gottlieb2, Iain McInnes3, Natalie J. Shiff4, Anthony Todd5, Emmanouil Rampakakis6, Francois Nantel7, Jenna Parrett5, Frederic Lavie8 and Proton Rahman9, 1Swedish Medical Center/Providence St. Joseph Health; University of Washington School of Medicine, Seattle, WA, 2Icahn School of Medicine at Mount Sinai, Department of Dermatology, Seattle, WA, 3University of Glasgow, College of Medical Veterinary and Life Sciences, Glasgow, United Kingdom, 4Janssen Scientific Affairs, LLC / University of Saskatchewan, Adjunct, Community Health and Epidemiology, Horsham, PA, 5Janssen Scientific Affairs, LLC, Horsham, PA, 6McGill University, Department of Pediatrics / Scientific Affairs, JSS Medical Research Inc., Montreal, QC, Canada, 7Nantel Medsci Consult, Montreal, QC, Canada, 8Janssen Cilag Global Medical Affairs, Immunology Global Medical Affairs, Issy les Moulineaux, France, 9Memorial University of Newfoundland, Faculty of Medicine, Division of Rheumatology, St. John's, Canada

    Background/Purpose: Guselkumab (GUS), a fully human IL-23p19-subunit inhibitor, has demonstrated multidomain efficacy (swollen/tender joints, psoriasis, enthesitis and dactylitis) in patients (pts) with active PsA in…
  • Abstract Number: 1680 • ACR Convergence 2024

    Reporting Quality of Non-inferiority and Equivalence Rheumatoid Arthritis Randomized Clinical Trials: A Systematic Review

    Osama Alalwan1 and Majeed Haider2, 1Salmaniya Medical Complex, Bahrain, Bahrain, 2Salmaniya Medical Complex, Manama, Bahrain

    Background/Purpose: The number of non-inferiority/equivalence randomized clinical trials (NI/EQ-RCTs) in the rheumatoid arthritis (RA) field has recently increased for various reasons. These designs require special…
  • Abstract Number: 2274 • ACR Convergence 2024

    Efficacy and Safety of the Biased Melanocortin Receptor Agonist AP1189/resomelagon in Combination with Methotrexate in DMARD-naïve Rheumatoid Arthritis Patients: The EXPAND Trial

    Asger Reinstrup Bihlet1, Philip G Conaghan2, Thomas Boesen3, Mette Arnum Jensen3, Alejandro Castillo Mondragón4, Ema Erkocevic Petersen4, Cathrine Borgsted Bak4 and Thomas EN Jonassen3, 1NBCD A/S, Soeborg, Denmark, 2Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, and NIHR Leeds Biomedical Research Centre, Leeds Teaching Hospitals NHS Trust, Leeds, United Kingdom, 3Synact Pharma ApS, Holte, Denmark, 4NBCD A/S, Soborg, Denmark

    Background/Purpose: AP1189 is a novel, first-in-class, oral, biased melanocortin (MC)1 and MC3 receptor agonist in development for Rheumatoid Arthritis (RA) treatment. Through multiple actions including…
  • Abstract Number: 2582 • ACR Convergence 2024

    Efficacy and Safety of Sonelokimab, a Novel IL-17A- and IL-17F-Inhibiting Nanobody, in Patients with Active PsA: 24-Week Results from a Global, Randomized, Double-Blind, Placebo-Controlled Phase 2 Trial

    Iain McInnes1, Laura Coates2, Philip Mease3, Alexis Ogdie4, Arthur Kavanaugh5, Lihi Eder6, Georg Schett7, Alan Kivitz8, Nuala Brennan9, Alex Godwood9, Eva Cullen9, Kristian Reich9, Christopher Ritchlin10 and Joseph F. Merola11, 1University of Glasgow, College of Medical Veterinary and Life Sciences, Glasgow, United Kingdom, 2University of Oxford, Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, Oxford, United Kingdom, 3Swedish Medical Center/Providence St. Joseph Health; University of Washington School of Medicine, Seattle, WA, 4Department of Medicine, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, 5University of California San Diego, La Jolla, CA, 6University of Toronto, Women’s College Hospital and Department of Medicine, Toronto, ON, Canada, 7Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany, 8Altoona Center for Clinical Research, Duncansville, PA, 9MoonLake Immunotherapeutics AG, Zug, Switzerland, 10Department of Medicine, Allergy, Immunology, and Rheumatology Division, University of Rochester Medical School, Canandaigua, NY, 11UT Southwestern Medical Center, Dallas, TX

    Background/Purpose: Sonelokimab is a novel humanized Nanobody designed to inhibit IL-17A and IL-17F and penetrate clinically relevant sites of inflammation. The 24-week Phase 2 ARGO…
  • « Previous Page
  • 1
  • 2
  • 3
  • 4
  • 5
  • 6
  • …
  • 19
  • Next Page »
Advanced Search

Your Favorites

You can save and print a list of your favorite abstracts during your browser session by clicking the “Favorite” button at the bottom of any abstract. View your favorites »

All abstracts accepted to ACR Convergence are under media embargo once the ACR has notified presenters of their abstract’s acceptance. They may be presented at other meetings or published as manuscripts after this time but should not be discussed in non-scholarly venues or outlets. The following embargo policies are strictly enforced by the ACR.

Accepted abstracts are made available to the public online in advance of the meeting and are published in a special online supplement of our scientific journal, Arthritis & Rheumatology. Information contained in those abstracts may not be released until the abstracts appear online. In an exception to the media embargo, academic institutions, private organizations, and companies with products whose value may be influenced by information contained in an abstract may issue a press release to coincide with the availability of an ACR abstract on the ACR website. However, the ACR continues to require that information that goes beyond that contained in the abstract (e.g., discussion of the abstract done as part of editorial news coverage) is under media embargo until 10:00 AM ET on November 14, 2024. Journalists with access to embargoed information cannot release articles or editorial news coverage before this time. Editorial news coverage is considered original articles/videos developed by employed journalists to report facts, commentary, and subject matter expert quotes in a narrative form using a variety of sources (e.g., research, announcements, press releases, events, etc.).

Violation of this policy may result in the abstract being withdrawn from the meeting and other measures deemed appropriate. Authors are responsible for notifying colleagues, institutions, communications firms, and all other stakeholders related to the development or promotion of the abstract about this policy. If you have questions about the ACR abstract embargo policy, please contact ACR abstracts staff at [email protected].

ACR Abstract Embargo Policy

Accepted abstracts are made available to the public online in advance of the meeting and are published in a special online supplement of Arthritis & Rheumatology. Information contained in those abstracts may not be released until the abstracts appear online. Academic institutions, private organizations and companies with products whose value may be influenced by information contained in an abstract may issue a press release to coincide with the availability of an ACR abstract on the ACR website. However, the ACR continues to require that information that goes beyond that contained in the abstract (e.g., discussion of the abstract done as part a scientific presentation or presentation of additional new information that will be available at the time of the meeting) is under embargo until Saturday, November 11, 2023.

Violation of this policy may result in the abstract being withdrawn from the meeting and other measures deemed appropriate. Authors are responsible for notifying financial and other sponsors about this policy. If you have questions about the abstract embargo policy, please contact the public relations department at [email protected].

Copyright Policy

View ACR Policies.

Wiley

  • Online Journal
  • Privacy Policy
  • Permissions Policies
  • Cookie Preferences

© Copyright 2025 American College of Rheumatology