Abstracts tagged "randomized"

Abstract Number: 1458 • ACR Convergence 2021
Sustained Efficacy and Safety of Iberdomide to Week 52 in Patients with Active Systemic Lupus Erythematosus (SLE) in a Phase 2, Randomized, Placebo-Controlled Study
Joan Merrill¹, Victoria Werth², Richard Furie³, Ronald van Vollenhoven⁴, Maria Majdan⁵, Michael Weiswasser⁶, Shimon Korish⁶, Zhaohui Liu⁶, Peter Schafer⁶ and Nikolay Delev⁶, ¹Oklahoma Medical Research Foundation, Oklahoma City, OK, ²Philadelphia VAMC, Philadelphia, PA, USA and Department of Dermatology, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, ³Zucker School of Medicine at Hofstra/Northwell, Great Neck, NY, ⁴Department of Rheumatology and Clinical Immunology, Amsterdam University Medical Center, Amsterdam Rheumatology Center, Amsterdam, Netherlands, ⁵Samodzielny Publiczny Szpital Kliniczny Nr 4 w Lublinie, Lublin, Poland, ⁶Bristol Myers Squibb, Princeton, NJ
Background/Purpose: We previously reported 24-wk results of a phase 2b trial of iberdomide, a high-affinity cereblon ligand that promotes proteasomal degradation of Ikaros (IKZF1) and…

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