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Abstracts tagged "race/ethnicity and rheumatoid arthritis"

  • Abstract Number: 519 • ACR/ARHP Annual Meeting 2015

    In Indigenous North Americans at High Risk for RA Complement C5 Level Is Associated with ACPA Positivity and C5a with Transition to Synovitis Even after Correcting for in Vitro Complement Activation Found with Prolonged Sample Storage

    Ceri Richards1, Carol Hitchon2, Xiaobo Meng3, Irene Smolik4, David Robinson4 and Hani S. El-Gabalawy4, 1Internal Medicine, University of Manitoba, Winnipeg, MB, Canada, 2Department of Rheumatology, University of Manitoba, Winnipeg, MB, Canada, 3University of Manitoba, Winnipeg, MB, Canada, 4Arthritis Center, University of Manitoba, Winnipeg, MB, Canada

    Background/Purpose: Complement activation, a key component of innate immunity and activator of adaptive immunity has been linked to RA pathogenesis. Anti-citrullinated peptide antibody (ACPA) and…

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