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Abstracts tagged "quality of life"

  • Abstract Number: 1152 • 2014 ACR/ARHP Annual Meeting

    Euroqol-5-Dimensions Utility Gain in Rheumatoid Arthritis, Treated with Abatacept, Rituximab, Tocilizumab or Tumor Necrosis Factor Inhibitors

    Anders Gülfe1, Johan A. Karlsson2 and Lars-Erik Kristensen3, 1Dept of Clinical Sciences, Lund, Section for Rheumatology, Lund University, Faculty of Medicine, Lund, Sweden, 2Dept of Clinical Sciences, Section for Rheumatology, Lund University, Faculty of Medicine, Lund, Sweden, 3Dept of Clinical Sciences, Lund, Section for Rheumatology, Lund University, Faculty of Medicine, Malmö, Sweden

    Background/Purpose: We have earlier demonstrated that EuroQoL-5-Dimensions (EQ-5D) utility improves rapidly after commencement of tumor necrosis factor inhibition (TNFi) in rheumatoid arthritis (RA) and other…
  • Abstract Number: 1150 • 2014 ACR/ARHP Annual Meeting

    Marked Differences in Euro-Qol-5-Dimensions Preference Sets Based on Hypothetical or Experience Based Valuation

    Anna Cooper1, Johan A. Karlsson2 and Anders Gülfe1, 1Dept of Clinical Sciences, Lund, Section for Rheumatology, Lund University, Faculty of Medicine, Lund, Sweden, 2Dept of Clinical Sciences, Section for Rheumatology, Lund University, Faculty of Medicine, Lund, Sweden

    Background/Purpose: Health related quality of life (HRQoL) can be expressed as utility, a value anchored at 0 (death) and 1 (perfect health, forming the basis…
  • Abstract Number: 1078 • 2014 ACR/ARHP Annual Meeting

    Work-Related Behavior and Experiences in Patients with Systemic Lupus Erythematosus

    Jutta G. Richter1, Ralph Brinks2, Thomas Muth3, Tobias Koch1, Peter Angerer3 and Matthias Schneider4, 1Department of Rheumatology, Heinrich-Heine-University Duesseldorf, Duesseldorf, Germany, 2Department of Rheumatology, Heinrich-Heine-University Duesseldorf, Düsseldorf, Germany, 3Institute for Occupational and Social Medicine, Heinrich-Heine-University Duesseldorf, Duesseldorf, Germany, 4Department of Rheumatology, Heinrich-Heine-University Duesseldorf, Duesseldorf, Germany

    Background/Purpose: Work-related behavior and experiences are discussed to be either risk factors or resources for individual‘s health. Diseases and related changing working conditions and/or experiences…
  • Abstract Number: 1077 • 2014 ACR/ARHP Annual Meeting

    A Real-World Characterization of US Patients with “Moderate-to-Severe” Systemic Lupus Erythematosus

    Vibeke Strand1, Jennifer Johnson2, Carl Vandeloo3, Catrinel Galateanu3 and Steve Lobosco2, 1Biopharmaceutical Consultant, Portola Valley, CA, 2Adelphi Real World Ltd., Macclesfield, United Kingdom, 3UCB Pharma, Brussels, Belgium

    Background/Purpose Systemic lupus erythematosus (SLE) is a chronic, inflammatory disease which can impact on patients' Health-Related Quality of Life (HRQoL). This analysis was designed to…
  • Abstract Number: 1057 • 2014 ACR/ARHP Annual Meeting

    Work-Related Behavior and Experiences in Patients with Rheumatoid Arthritis

    Jutta G. Richter1, Thomas Muth2, Ralph Brinks3, Tobias Koch1, Peter Angerer2 and Matthias Schneider4, 1Department of Rheumatology, Heinrich-Heine-University Duesseldorf, Duesseldorf, Germany, 2Institute for Occupational and Social Medicine, Heinrich-Heine-University Duesseldorf, Duesseldorf, Germany, 3Department of Rheumatology, Heinrich-Heine-University Duesseldorf, Düsseldorf, Germany, 4Department of Rheumatology, Heinrich-Heine-University Duesseldorf, Duesseldorf, Germany

    Background/Purpose: Work-related behavior and experiences are discussed to be either risk factors or resources for individual‘s health. Diseases and related changing working conditions and/or experiences…
  • Abstract Number: 2607 • 2013 ACR/ARHP Annual Meeting

    Evaluation Of The Construct Validity Of The Patient-Reported Outcomes Measurement Information System (PROMIS®) Gastrointestinal (GI) Symptoms Measures In Systemic Sclerosis (SSc)

    Dinesh Khanna1, Puja Khanna1, Brennan Spiegel2, Lin Chang3, Gil Y. Melmed4, Roger Bolus5 and Ron Hays6, 1Division of Rheumatology, University of Michigan Medical Center, Ann Arbor, MI, 2Gastroenterology; Health Policy and Management, Cedars-Sinai Health System and UCLA School of Medicine and Public Health, Los Angeles, CA, 3Medicine, Division of Digestive Diseases, David Geffen School of Medicine at University of California, Los Angeles, Los Angeles, CA, 4Inflammatory Bowel Disease Center, Cedar-Sinai Medical Center, Los Angeles, CA, 5Research Solutions Group, Encinitas, CA, 6Medicine, University of California, Los Angeles, Los Angeles, CA

    Background/Purpose: As part of the National Institutes of Health PROMIS¨ roadmap initiative, we developed GI Symptoms measures that assess 8 domains: Gastroesophageal reflux (13 items),…
  • Abstract Number: 2530 • 2013 ACR/ARHP Annual Meeting

    Sustained Improvements In Health-Related Quality Of Life In Patients With Systemic Lupus Erythematosus following Epratuzumab Treament: Results from a Phase IIb Trial and Its Open-Label Extension

    Vibeke Strand1, Joan T. Merrill2, Enkeleida Nikaï3, Brian Kilgallen4, Antoine Regnault5 and Caroline Gordon6, 1Stanford University, Palo Alto, CA, 2Clinical Pharmacology Research Program, Oklahoma Medical Research Foundation, Oklahoma City, OK, 3UCB Pharma, Brussels, Belgium, 4UCB Pharma, Raleigh, NC, 5Mapi HEOR & Strategic Market Access, Lyon, France, 6Rheumatology Research Group (East Wing), School of Immunity and Infection, University of Birmingham, Birmingham, United Kingdom

    Background/Purpose: Epratuzumab is a monoclonal antibody targeting CD22. Improvements in health-related quality of life (HRQoL) with epratuzumab in patients with systemic lupus erythematosus (SLE) have…
  • Abstract Number: 2504 • 2013 ACR/ARHP Annual Meeting

    Male Children With Higher SLE Disease Activity In An US Cohort

    Lakshmi N. Moorthy1, Elizabeth Roy2, Margaret Peterson3, Afton L. Hassett4, Alexa B. Adams5, Laura V. Barinstein6, Elizabeth C. Chalom7, Karen Onel8, Linda Ray9, Jorge Lopez-Benitez10, Kathleen A. Haines11, Philip Hashkes12, Daniel J. Kingsbury13, Victoria Cartwright14, Nora G. Singer15, Ingrid Tomanova-Soltys16, Andreas Reiff17, Sandy D. Hong18 and Thomas J. A. Lehman19, 1Pediatric Rheumatology, Robert Wood Johnson Medical School-Rutgers University, New Brunswick, NJ, 2RWJMS-UMDNJ, New Brunswick, NJ, 3Hospital for Special Surgery, New York, NY, 4Anesthesiology, University of Michigan, Ann Arbor, MI, 5Pediatric Rheumatology, Hospital for Special Surgery, New York, NY, 6Pediatric Rheumatology, Mount Sinai Med Ctr, New York, NY, 7Pediatrics, St. Barnabas Medical Center, Livingston, NJ, 8Pediatric Rheumatology, University of Chicago Hospitals, Chicago, IL, 9Pediatric Rheumatology, University of Mississippi Medical Center, Jackson, MS, 10Pediatric Rheumatology Program Centro Medico La Costa, Asuncion, Paraguay, 11Department of Pediatrics, Joseph M Sanzari Children’s Hospital, Hackensack University Medical Center, Hackensack, NJ, 12Pediatric Rheumatology, Shaare Zedek Medical Center, Jerusalem, Israel, 13Randall Children's Hospital at Legacy Emanuel, Portland, OR, 14Legacy Emanuel Children's Hospital, Portland, OR, 15Medicine, Division of Rheumatology, MetroHealth Medical Center, Cleveland, OH, 16Winthrop University Hospital, Mineola, NY, 17Division of Rheumatology, Children's Hospital Los Angeles, Los Angeles, CA, 18Pediatrics-Rheumatology, U of Iowa Children's Hosp, Iowa City, IA, 19Chief Div Ped Rheum PTD, Hospital for Special Surgery, New York, NY

    Background/Purpose: Although systemic lupus erythematosus (SLE) is more common in females, males tend to have more severe disease. We compared age at SLE diagnosis, duration,…
  • Abstract Number: 1996 • 2013 ACR/ARHP Annual Meeting

    Racial/Ethnicity Differences In Health-Related Quality Of Life (HRQOL), Functional Ability and Health Care Utilization In Gout Patients

    Aseem Bharat1, Jasvinder A. Singh2,3, Puja Khanna4, Cleopatra Aquino-Beaton5, Jay E. Persselin6, Erin Duffy7, David Elashoff8 and Dinesh Khanna9, 1Medicine/Rheumatology, University of Alabama at Birmingham, Birmingham, AL, 2Rheumatology, Birmingham VA, Birmingham, AL, 3Department of Medicine, University of Alabama, Tuscaloosa, AL, 4Division of Rheumatology, University of Michigan Medical Center, Ann Arbor, MI, 5Rheumatology, VA Greater Los Angeles Healthcare System, Los Angeles, CA, 6Medicine W-111J Div of Rheum, VA Greater Los Angeles Healthcare System, Los Angeles, CA, 7Medicine, University of California Los Angeles, Los Angeles, CA, 8Medicine- Statistic Core, UCLA Department of Medicine Statistics Core, Los Angeles, CA, 9University of Michigan, Ann Arbor, MI

    Background/Purpose: Due to limited/no data for race/ethnicity, our objective was to assess whether HRQOL functional ability and health care utilization in gout patients differs by…
  • Abstract Number: 1520 • 2013 ACR/ARHP Annual Meeting

    Reduction Of Disease Burden On Workplace and Household Productivity In Axial Spondyloarthritis, Including Ankylosing Spondylitis and Non-Radiographic Axial Spondyloarthritis, Over 48 Weeks Of Treatment With Certolizumab Pegol

    Désirée M. van der Heijde1, Jürgen Braun2, Martin Rudwaleit3, Oana Purcaru4 and Arthur Kavanaugh5, 1Dept of Rheumatology, Leiden University Medical Center, Leiden, Netherlands, 2Rheumazentrum Ruhrgebiet, Herne, Germany, 3Endokrinologikum, Berlin, Germany, 4UCB Pharma, Brussels, Belgium, 5Division of Rheumatology Allergy and Immunology, University of California San Diego, San Diego, CA

    Background/Purpose: Axial spondyloarthritis (axSpA) includes both ankylosing spondylitis (AS, meeting modified New York criteria) and axSpA with no sacroiliitis on X-ray (non-radiographic axSpA, nr-axSpA). AS…
  • Abstract Number: 1028 • 2013 ACR/ARHP Annual Meeting

    Development Of Patient-Reported Outcomes Measurement Information System (PROMIS®) Gastrointestinal (GI) Symptoms Item Bank

    Dinesh Khanna1, Lin Chang2, Gil Y. Melmed3, Roger Bolus4, Puja Khanna1, Ron Hays5 and Brennan Spiegel6,7, 1Division of Rheumatology, University of Michigan Medical Center, Ann Arbor, MI, 2Medicine, Division of Digestive Diseases, David Geffen School of Medicine at University of California, Los Angeles, Los Angeles, CA, 3Inflammatory Bowel Disease Center, Cedar-Sinai Medical Center, Los Angeles, CA, 4Research Solutions Group, Encinitas, CA, 5Medicine, University of California, Los Angeles, Los Angeles, CA, 6Gastroenterology; Health Policy and Management, Cedars-Sinai Health System and UCLA School of Medicine and Public Health, Los Angeles, CA, 7VA Greater Los Angeles Healthcare System, Los Angeles, CA

    Background/Purpose: The National Institutes of Health PROMIS® roadmap initiative is a cooperative research program designed to develop, evaluate, and standardize item banks to measure patient-reported…
  • Abstract Number: 2424 • 2012 ACR/ARHP Annual Meeting

    Sleep Disturbances in Systemic Sclerosis: Evidence for the Role of Gastrointestinal Symptoms, Pain, and Pruritus

    Katherine Milette1, Marie Hudson2, Annett Koerner1, Murray Baron3 and Brett D. Thombs4, 1Educational and Counselling Psychology, McGill University, Montreal, QC, Canada, 2Jewish General Hospital, McGill University, Montreal, QC, Canada, 3Pavillion A, Rm 216, Lady David Institute for Medical Research and Jewish General Hospital, Montreal, QC, Canada, 4Psychiatry, McGill University, Montreal, QC, Canada

    Background/Purpose: Systemic Sclerosis (SSc) is an autoimmune connective tissue disorder characterized by thickening and fibrosis of the skin and internal organs. There is significant mortality…
  • Abstract Number: 1831 • 2012 ACR/ARHP Annual Meeting

    Evaluation of the Cost-Effectiveness of Rheumatoid Arthritis Treatment with Biologic Agents Using the IORRA Cohort Database

    Eiichi Tanaka1, Eisuke Inoue2, Daisuke Hoshi3, Akiko Kobayashi2, Naoki Sugimoto2, Kumi Shidara2, Eri Sato3, Yasushi Inoue3, Yohei Seto2, Ayako Nakajima4, Shigeki Momohara3, Atsuo Taniguchi2 and Hisashi Yamanaka3, 1Tokyo Women's Medical University, Tokyo, Japan, 2Institute of Rheumatology, Tokyo Women’s Medical University, Tokyo, Japan, 3Institute of Rheumatology, Tokyo Women's Medical University, Tokyo, Japan, 4Rheumatology, Institute of Rheumatology, Tokyo Women’s Medical University, Tokyo, Japan

    Background/Purpose: Rheumatoid arthritis (RA), a chronic inflammatory disorder, causes a significant decrease in quality of life. Recently developed biologic agents (BAs) have caused a considerable…
  • Abstract Number: 1740 • 2012 ACR/ARHP Annual Meeting

    Impairment of Quality of Life in Patients with Antiphospholipid Syndrome

    Stephane Zuily1, Francis Guillemin2, Veronique Regnault3, Pierre Kaminsky4, Patrick Mismetti5, Jacques Ninet6, Nicolas Baillet7, Nadine Magy-Bertrand8, Bernard Lorcerie9, Jean-Louis Pasquali10, Thomas Lecompte11, Anne-Christine Rat12 and Denis Wahl13, 1CHU de Nancy, Vascular Medicine Division and Regional Competence Center For Rare Vascular And Systemic Autoimmune Diseases, Nancy, F-54000, France; Inserm, UMR_S 1116, Nancy, F-54000, France; Université de Lorraine, Nancy, F-54000, France, Nancy, France, 2INSERM, Centre d'Investigation Clinique - Epidémiologie Clinique (CIC-EC) CIE6, Nancy, France, 3Inserm, UMR_S 1116, Nancy, F-54000, France; Université de Lorraine, Nancy, F-54000, France; CHU de Nancy, Contrat d’interface, Nancy, F-54000, France, Nancy, France, 4Internal Medicine, Orphan disease Unit, Nancy, France, 5CHU Saint-Etienne, Unité de Pharmacologie Clinique, Groupe de Recherche sur la Thrombose (EA 3065), Saint Etienne, France, 6Department of Nephrology and Internal Medicine, Hôpital Edouard Herriot, Lyon, France, Lyon, France, 7Hôpitaux civils de Colmar, Service de Médecine interne, Colmar, France, 8CHU Jean-Minjoz, Service de médecine interne et immunologie clinique, Besançon, France, 9Hopital Du Bocage, Service de Médecine Interne et Immunologie Clinique, Dijon, France, 10Strasbourg University, Hospital, CNRS UPR 3572, Strasbourg, France, 11Inserm, UMR_S 1116, Nancy, F-54000, France; Université de Lorraine, Nancy, F-54000, France; CHU de Nancy, Haematology Laboratory, Nancy, F-54000, France; Division of Haematology, HUG, Geneva, Switzerland (current address), Geneva, Switzerland, 12Université de Lorraine, INSERM, CIC-EC CIE6, Rheumatology, Epidemiology, Nancy, France, 13Nancy University Hospital and INSERM U961, Vascular medicine division and Regional Competence Center For Rare Vascular And Systemic Autoimmune Diseases, Nancy, France

    Background/Purpose : Quality of life (QoL) is an important outcome in clinical care especially in patients with chronic disease such as systemic lupus erythematosus (SLE).…
  • Abstract Number: 1558 • 2012 ACR/ARHP Annual Meeting

    “It Gets Me Down Every Single Day”: Are Men with Rheumatoid Arthritis Getting the Support They Need?

    Caroline A. Flurey1, Marianne Morris2, Jon Pollock1, Rodney A. Hughes3, Pamela Richards4 and Sarah Hewlett5, 1Faculty of Health and Life Sciences, University of the West of England, Bristol, United Kingdom, 2University of the West of England, Bristol, United Kingdom, 3Rheumatology, St. Peters Hospital, Chertsey Surrey, United Kingdom, 4Academic Rheumatology Unit, University of Bristol, Bristol, United Kingdom, 5Academic Rheumatology, University of the West of England, Bristol, United Kingdom

    Background/Purpose: Daily life with RA has been explained as unpredictable and full of uncertainty. However, most research about daily life with RA was conducted before…
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