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Abstracts tagged "quality of life"

  • Abstract Number: 2384 • ACR Convergence 2025

    Patient-Reported Quality of Life in SLE: Association with Biomarker-Derived Disease Activity Index (L-DAI) and hSLEDAI in a Prospective Cohort

    Bernard Rubin1, Rou Sore1, Melissa Munroe1, Daniele DeFreese1, Adrian Holloway1, Mohan Purushothaman1, Yangfen Li2, Hu Zeng2, Uma Thanarajasingam2, Judith James3 and Eldon Jupe1, 1Progentec Diagnostics, Inc., Oklahoma City, OK, 2Mayo Clinic, Rochester, MN, 3Oklahoma Medical Research Foundation, Oklahoma City, OK

    Background/Purpose: Systematic lupus erythematosus (SLE) is a multisystem autoimmune disease characterized by unpredictable disease activity. The Lupus Disease Activity Index (L-DAI) is a blood-based assessment…
  • Abstract Number: 1551 • ACR Convergence 2025

    Disease Burden and Treatment Preferences for Systemic Lupus Erythematosus: Results from a Global Real-World Survey

    Zahi Touma1, Christopher Saffore2, Karim Masri3, Jerry Clewell3, Emily Goddard4, Grace O'Neill4, Madelane Foxall4 and Karen H. Costenbader5, 1University of Toronto, Toronto, ON, Canada, 2AbbVie Inc., waukegan, IL, 3AbbVie Inc., North Chicago, IL, 4Adelphi Real World, Bollington, United Kingdom, 5Harvard Medical School and Brigham and Women's Hospital, Boston, MA

    Background/Purpose: As new treatment options for systemic lupus erythematosus (SLE) become available, understanding patient burden and preferences is key to optimizing shared decision-making. This study…
  • Abstract Number: 1259 • ACR Convergence 2025

    Patient and Caregiver Perspectives on the Burden of Disease in Uncontrolled Gout: A Cross-Sectional Survey Study

    Angelo Gaffo1, Bhavisha Desai2, Abiola Oladapo3, Nana Kragh4, Rebekah Zincavage5, Brad Padilla5 and Naomi Schlesinger6, 1Division of Rheumatology and Clinical Immunology, University of Alabama, Birmingham, AL, USA; Birmingham VA Medical Center, Birmingham, AL, USA, Birmingham, AL, 2Sobi, Glastonbury, CT, 3Sobi INC, Waltham, MA, 4Sobi, Kongens Lyngby, Denmark, 5Stratevi, Boston, 6Spencer Fox Eccles School of Medicine, University of Utah, Salt Lake City, UT, USA, Salt Lake City, UT

    Background/Purpose: Many patients with uncontrolled gout (UG) experience symptoms despite being on urate-lowering therapy (ULT), often requiring support from informal caregivers. UG impacts patients and…
  • Abstract Number: 0794 • ACR Convergence 2025

    Using Artificial Intelligence to Analyze Multilingual Qualitative Data in Lupus Pregnancy Research: A Proof of Concept with Large Language Models

    Romina Boers1, Grace Terry2 and Bella Mehta3, 1Weil Cornell Medicine, New York, 2Weil Cornell Medicine, Ne wYork, 3Hospital for Special Surgery, Weill Cornell Medicine, Jersey City, NJ

    Background/Purpose: Women with systemic lupus erythematosus (SLE), particularly those of childbearing age, face heightened risks during pregnancy, including disease flares, adverse maternal-fetal outcomes, and emotional…
  • Abstract Number: 2341 • ACR Convergence 2025

    Bimekizumab Treatment Resulted in Long-Term Sustained Reductions in Disease Impact Assessed by the Psoriatic Arthritis Impact of Disease (PsAID)-12 Questionnaire in Patients with Active Psoriatic Arthritis: Up to 3-Year Results from Two Phase 3 Studies

    Ana-Maria Orbai1, Dafna D. Gladman2, Laura Coates3, Maarten de Wit4, Barbara Ink5, Rajan Bajracharya5, Patrick Healy6, Jérémy Lambert7 and Laure Gossec8, 1Division of Rheumatology, Johns Hopkins University School of Medicine, Baltimore, MD, 2Schroeder Arthritis Institute, Krembil Research Institute, Toronto Western Hospital, Division of Rheumatology, Toronto, ON, Canada, 3Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, Oxford, England, United Kingdom, 4Patient Research Partner, Stichting Tools, Amsterdam, Netherlands, 5UCB, Slough, England, United Kingdom, 6UCB, Morrisville, NC, 7UCB, Colombes, France, 8Sorbonne Universite and Pitie-Salpetriere Hospital, Paris, France

    Background/Purpose: Bimekizumab (BKZ) is a monoclonal IgG1 antibody that selectively inhibits interleukin (IL)-17F in addition to IL-17A. The PsA Impact of Disease-12 (PsAID-12) questionnaire is…
  • Abstract Number: 1503 • ACR Convergence 2025

    Lupus Disease Activity Adversely Affects the Quality of Life but not Intimate Relationship and Sexual Function in Indian Female Lupus Patients

    Ranjan Gupta, Nilanchali Singh, Nisha Jawaliya, Rudra Prosad Goswami, Soniya Dhiman and Parul baisoya, All India Institute of Medical Sciences, New Delhi, Delhi, India

    Background/Purpose: Systemic Lupus Erythematosus (SLE) disease activity can affect the normal functioning of the patients. This functioning in various domains can be assessed using quality…
  • Abstract Number: 1254 • ACR Convergence 2025

    Symptom Burden and Treatment Experience in Fibromyalgia: Results From a National Patient Survey

    Lesley Arnold1, Zhao Yang2, Parul Houston2, Todd Grinnell2 and Daniel Clauw3, 1University of Cincinnati College of Medicine, Cincinnati, OH, 2Axsome Therapeutics, Inc, New York, NY, 3Chronic Pain and Fatigue Research Center, University of Michigan, Ann Arbor, MI

    Background/Purpose: Fibromyalgia (FM) is a chronic, widespread pain disorder driven by dysregulated central pain processing which substantially impairs daily function and quality of life. Approved…
  • Abstract Number: 0789 • ACR Convergence 2025

    Short Form 36 (SF-36) Health Survey Questionnaire in Health-Related Quality of Life Assessment in Patients with Inflammatory Myopathies

    Almurtada Razok1, Jasmin Taylor2, Ethan Ritz3, Kristin Wipfler4, Kaleb Michaud5 and Didem Saygin6, 1John H Stroger Jr Hospital of Cook County, Chicago, IL, 2Rush Medical College, Chicago, IL, 3Rush Research Informatics Core, Rush University Medical Center, Chicago, IL, 4FORWARD, The National Databank for Rheumatic Diseases, Omaha, NE, 5University of Nebraska Medical Center, Omaha, NE, 6Rush University Medical Center, Chicago, IL

    Background/Purpose: Patients with idiopathic inflammatory myopathies (IIM) experience significant impairment in their health-related quality of life (QoL); however, there are currently no validated measures to…
  • Abstract Number: 2337 • ACR Convergence 2025

    A Mediation Analysis of Tofacitinib’s Effects on SF-36: The Roles of Fatigue, Pain, Stiffness, and Mobility in Ankylosing Spondylitis

    Xenofon Baraliakos1, Andrew G. Bushmakin2, Joseph C. Cappelleri2, Eleni Nikitopoulou3, You-Li Ling4, Mostafa Zayed5 and Jonathan Dominick Cicci6, 1Rheumazentrum Ruhrgebiet Herne, Ruhr-University Bochum, Herne, Germany, 2Pfizer Inc., Groton, CT, 3Pfizer Hellas, Athens, Greece, 4Pfizer Inc, New York, NY, USA, New York, NY, 5Pfizer Gulf FZ LLC, Dubai, United Arab Emirates, 6Pfizer Inc., New York, NY

    Background/Purpose: Mediation modeling is used to determine mechanisms underlying the relationship between independent and dependent variables via other explanatory variables (“mediators”). Fatigue, pain, and morning…
  • Abstract Number: 1487 • ACR Convergence 2025

    Whole Health Empowerment for Endotypes of Lupus (WHEEL) Program: User Testing Findings on Feasibility, Acceptability, and Opportunities for Intervention Refinement

    Jennifer Rogers1, Amanda Eudy2, Connor Drake3, Tamara Somers4, David Pisetsky5, Christie Clipper6, Ralph Snyderman7, Anna Batsakes6, Leigh Saner6, Dana Burshell3, Mithu Maheswaranathan4, Lisa Criscione-Schreiber4, Rebecca Sadun8, Nathaniel Harris5, Kai Sun8, Kelsey Dunn6, Jenny Herndon6, Vonne Jacobs6 and Megan Clowse9, 1Duke, Durham, NC, 2Duke University, Raleigh, NC, 3Duke University School of Medicine, Durham, 4Duke University School of Medicine, Durham, NC, 5Duke University Medical Center, Durham, NC, 6Duke University, Durham, 7Duke Center for Personalized Health Care, Durham, NC, 8Duke University, Durham, NC, 9Duke University, Chapel Hill, NC

    Background/Purpose: To improve quality of life (QoL) in individuals with SLE, we developed the Whole Health Empowerment for Endotypes of Lupus (WHEEL) program—a 4-month, biweekly,…
  • Abstract Number: 1253 • ACR Convergence 2025

    Patient Reported Outcome Measures: Assessing Resident Physician Acceptance of the Routine Assessment of Patient Index Data 3 Survey and its Impact on Physician-Patient Relationship

    Nisha Sapkota1, Chana Birnbaum2, Henna Levitansky2, Yevheniia Andriushchenko2, Saadia Malik2, Melissa Andrade2, Sarang Choi2 and Sima Terebelo2, 1Interfaith Medical Center, One Broolyn Health, Brooklyn, NY, 2Brookdale Hospital Medical Center, One Brooklyn Health, Brooklyn

    Background/Purpose: When treating patients with rheumatological conditions, building a strong physician-patient relationship plays an important role in determining disease outcomes. The Routine Assessment of Patient…
  • Abstract Number: 0767 • ACR Convergence 2025

    Quality of Life in Patients with Rheumatoid Arthritis with Foot and Ankle Involvement

    Egla Samantha Sanchez-Peralta1, Andrea Cantero-Castro2, Karina Deciderio-Pavon3, Jesús Gilberto Espinoza-Gámez3, Irasema Arcibar-Liceaga3, Carolina De Leon-Carrillo3, Angel Kevin Garza-Elizondo1, Ryan Jared Sanchez-De la Cruz3, Jesus Alberto Cardenas-de la Garza4, Dionicio A. Galarza-Delgado5, Diana E. Flores-Alvarado1 and Jorge Alberto Elizondo-Rodriguez2, 1Rheumatology Service, University Hospital “Dr. José Eleuterio González”, Universidad Autónoma de Nuevo León, Monterrey, México, Monterrey, Nuevo Leon, Mexico, 2Traumatology Service, Hospital Universitario "Dr. José Eleuterio González", Monterrey, Nuevo Leon, Mexico, 3Rheumatology Service, Hospital Universitario "Dr. José Eleuterio González", Monterrey, Nuevo Leon, Mexico, 4Rheumatology Service, University Hospital “Dr. José Eleuterio González”, Universidad Autónoma de Nuevo León, Monterrey, México, Monterrey, Mexico, 5Rheumatology Service, Hospital Universitario Dr. José Eleuterio González, Universidad Autónoma de Nuevo León, Monterrey, Mexico

    Background/Purpose: Foot and ankle involvement in patients with rheumatoid arthritis is a common yet often underexplored and underrecognized manifestation. This can negatively affect patients' quality…
  • Abstract Number: 2326 • ACR Convergence 2025

    Impact of Regular Exercise, Mobility Impairment, and Obesity on Quality of Life in Patients with Axial Spondyloarthritis: A Cross-Sectional Analysis from the Brazilian Registry of Spondyloarthritis

    Rafael Bassara Macedo1, Maria Eduarda Veiga2, Gustavo Resende3, Marcelo Pinheiro4, Claudia Marques5, Adriana Marinho6, Andressa Soares7, Cleandro Pires8, Débora Rodrigues9, Eduarda Souza10, Glaucio Castro11, Guilherme Bulbol12, Jamile Carneiro13, José Mauro Fernandes14, Manuella Ochtrop15, Maria Bernadete Gavi16, Michel Yazbek17, Nara Cavalcanti18, Natalia Machado19, Olivio Malheiro20, Rejane Vieira21, Ricardo Lage20, Rita Menin22, Rywka Golebiovski23, Sandra Ribeiro12, Thauana Oliveira23, Valquiria Diniz16, Percival Sampaio-Barros24 and Carla Saad2, 1Rheumatology Division, Hospital das Clinicas da Faculdade de Medicina da Universidade de Sao Paulo (USP), Sao Paulo, Sao Paulo, Brazil, 2Rheumatology Division, Hospital das Clinicas HCFMUSP, Faculdade de Medicina, Universidade de Sao Paulo, Sao Paulo, SP, Brazil, Sao Paulo, Brazil, 3Hospital das Clinicas UFMG, Belo Horizonte, Brazil, 4UNIFESP/ EPM, São Paulo, São Paulo, Brazil, 5Hospital das Clinicas - Universidade Federal de Pernambuco - UFPE, Recife, Pernambuco, Brazil, 6Fundação Hospital do Acre - AC, Rio Branco, Brazil, 7Hospital Universitário da Universidade Federal de Santa Catarina (UFSC) - SC, Florianópolis, Brazil, 8UNB, Brasilia, Distrito Federal, Brazil, 9Fundação Hospital do Acre - AC, Rio Branco, Acre, Brazil, 10Faculdade de Medicina da Universidade Federal do Amazonas (UFAM) - AM, Manaus, Brazil, 11Hospital Governador Celso Ramos (HCR) - SC, Florianópolis, Santa Catarina, Brazil, 12Faculdade de Medicina da Universidade Federal do Amazonas (UFAM) - AM, Manaus, Amazonas, Brazil, 13Hospital de Base do Distrito Federal (HBDF) - DF, Brasilia, Distrito Federal, Brazil, 14Universidade Federal do Maranhão (UFMA) - MA, São Luiz, Maranhao, Brazil, 15Hospital Universitário Pedro Ernesto / UERJ - RJ, Rio de Janeiro, Rio de Janeiro, Brazil, 16Universidade Federal do Espírito Santo (UFES) - ES, Vitória, Espirito Santo, Brazil, 17Universidade Estadual de Campinas (UNICAMP) - SP, Campinhas, Sao Paulo, Brazil, 18Hospital das Clínicas da Universidade Federal de Pernambuco (UFPE) - PE, Recife, Pernambuco, Brazil, 19Universidade Fedral do Paraná (UFPR) - PR, Curitiba, Parana, Brazil, 20Hospital das Clínicas da Universidade Federal de Minas Gerais (UFMG) - MG, Belo Horizonte, Minas Gerais, Brazil, 21Universidade Estadual do Ceará (UECE) - CE, Fortaleza, Ceara, Brazil, 22Faculdade de Medicina de São José do Rio Preto (FAMERP) - SP, São José do Rio Preto, Sao Paulo, Brazil, 23Escola Paulista de Medicina (EPM) - Universidade Federal de São Paulo (UNIFESP) - SP, São Paulo, Sao Paulo, Brazil, 24Rheumatology Division, Hospital das Clinicas HCFMUSP, Faculdade de Medicina, Universidade de Sao Paulo, Sao Paulo, SP, Brazil, São Paulo, Brazil

    Background/Purpose: Axial Spondyloarthritis (axSpA) is a chronic inflammatory disease that impairs quality of life. While pharmacological treatment is central to axSpA management, non-pharmacological strategies are…
  • Abstract Number: 1461 • ACR Convergence 2025

    Digital Behavioral Therapy Improves Outcome in Patients With Axial Spondyloarthritis And Persistent Pain: Results From a Randomized Controlled Trial

    David Kiefer1, Yade Sonkaya2, Dietmar Krause3, Markus Voglau4, Bernhard Mintrop5, Imke Redeker6, Xenofon Baraliakos7 and Uta Kiltz7, 1Ruhr-Universität Bochum; Private practice of rheumatology, Hattingen, Germany, Herne, Germany, 2Ruhr-Universität Bochum, Herne, Germany, 3Elisabeth-Gruppe, Herne, Germany, Essen, Germany, 4myself, Oldenburg, Germany, 5Private rheumatology practice, Hattingen, Germany, 6Ruhr University Bochum, Bochum, Germany, 7Rheumazentrum Ruhrgebiet Herne, Ruhr-University Bochum, Herne, Germany

    Background/Purpose: Axial spondyloarthritis (axSpA) is often associated with persistent pain despite effective anti-inflammatory treatment, substantially impacting patients' quality of life. Digital health applications (DiGAs) provide…
  • Abstract Number: 1248 • ACR Convergence 2025

    Patient and Clinician Perception and Use of Complementary and Alternative (CAM) Medicine for Rheumatic Disease

    Ailia Ali1, Sarah Sun1, Faryal Shaikh1, Tamiko Katsumoto2, Neha Shah3, Kimberly Trotter1 and Pankti Reid4, 1University of Chicago, Chicago, IL, 2Division of Immunology and Rheumatology, Stanford University, Millbrae, CA, 3Stanford University, Palo Alto, CA, 4University of Chicago Medical Center, Chicago, IL

    Background/Purpose: Complementary and alternative medicine (CAM) use is increasingly prevalent among patients with rheumatic diseases, yet alignment between patient practices and clinician perspectives remains poorly…
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