ACR Meeting Abstracts

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Abstracts tagged "pulmonary fibrosis and scleroderma"

  • Abstract Number: 1711 • 2017 ACR/ARHP Annual Meeting

    SIRT1 May Protect Against Systemic Sclerosis-Related Pulmonary Fibrosis By Decreasing Pro-Inflammatory and Pro-Fibrotic Processes

    Haiyan Chu1, Shuai Jiang2, Qingmei Liu3, Feng Qian4, Xiaodong Zhou5, Maureen D. Mayes6, Li Jin7 and Jiucun Wang8, 1MOE Key Laboratory of Contemporary Anthropology, State Key Laboratory of Genetic Engineering and Ministry of Education Key Laboratory of Contemporary Anthropology, Collaborative Innovation Center for Genetics and Development, School of Life Sciences, Fudan University, Shanghai, China, 2State Key Laboratory of Genetic Engineering and Ministry of Education Key Laboratory of Contemporary Anthropology, Collaborative Innovation Center for Genetics and Development, School of Life Sciences, Fudan University, Shanghai, China, 3State Key Laboratory of Genetic Engineering and Ministry of Education Key Laboratory of Contemporary Anthropology, Collaborative Innovation Center for Genetics and Development, School of Life Sciences, Fudan University, Shanghai, Chile, 4Ministry of Education Key Laboratory of Contemporary Anthropology, School of Life Sciences, Fudan University, Shanghai, China, 5Internal Medicine-Rheumatology, University of Texas McGovern Medical School, Houston, TX, 6University of Texas McGovern Medical School, Houston, TX, 7State Key Laboratory of Genetic Engineering, Collaborative Innovation Center for Genetics and Development, School of Life Sciences, Fudan University, Shanghai, China, 8State Key Laboratory of Genetic Engineering, Collaborative Innovation Center for Genetics and Development, School of Life Sciences, Fudan University, Shanghai, CN

    Background/Purpose: Interstitial lung disease (ILD) is the leading cause of death in systemic sclerosis (SSc).  Sirtuin1 (SIRT1) is a deacetylase with known anti-inflammatory and anti-fibrotic…
  • Abstract Number: 847 • 2016 ACR/ARHP Annual Meeting

    Forced Vital Capacity Predicts Lung Fibrosis Progression and Mortality in Systemic Sclerosis

    Anna Hoffmann-Vold1, Elizabeth R. Volkmann2, Oyvind Midtvedt3, Torhild Garen3, Anders Heiervang Tennøe3, Trond Mogens Aalokken4, May Brit Lund5 and Øyvind Molberg3, 1Division of Rheumatology, Oslo University Hospital, Oslo, Norway, 2University of California, Los Angeles, David Geffen School of Medicine, Los Angeles, CA, 3Rheumatology, Oslo University Hospital, Oslo, Norway, 4Radiology, Oslo University Hospital, Oslo, Norway, 5Respiratory Medicine, Oslo University Hospital, Oslo, Norway

    Background/Purpose:  Systemic sclerosis (SSc) carries high risk for progressive interstitial lung disease (ILD), but there are no valid methods for early detection of SSc-ILD or…
  • Abstract Number: 972 • 2016 ACR/ARHP Annual Meeting

    Outcome of the Scleroderma Population “at Risk” to Develop Pulmonary Hypertension in the Pulmonary Hypertension Assessment and Recognition of Outcomes in Scleroderma Cohort Study

    Vivien Hsu1, Virginia D. Steen2 and PHAROS Investigators, 1Rheumatology, RWJ Med Schl Scleroderma Prog, New Brunswick, NJ, 2Rheumatology, Georgetown University Medical Center, Washington, DC

    ABSTRACT: Background/Purpose: We investigated predictors of outcome, including mortality and cardiopulmonary hospitalizations in the Òat riskÓ group for pulmonary hypertension in PHAROS, a prospective longitudinal…
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