Abstracts tagged "Psoriatic arthritis"

Abstract Number: 2491 • 2012 ACR/ARHP Annual Meeting
IL-17 Expression Is Low in Psoriatic Arthritis Synovium Compared to Expression in Matched Skin Lesions
Jennifer Belasco¹, Hiroshi Mitsui¹, Mayte Suarez-Farinas¹, James S. Louie², Nathan Wei³, Nicholas Gulati¹ and James G. Krueger¹, ¹Krueger Laboratory, The Rockefeller University, New York, NY, ²Rheumatology, UCLA School of Medicine, Los Angeles, CA, ³Arthritis Treatment Center, Frederick, MD
Background/Purpose: Psoriatic arthritis (PsA) is an inflammatory joint disease associated with psoriasis. It is known that treatment modalities are not equally effective for both skin…
Abstract Number: 537 • 2012 ACR/ARHP Annual Meeting
The Association of alpha7 Nicotinic Acetylcholine Receptor Polymorphisms with Psoriatic Arthritis and Its Interaction with Smoking
Lihi Eder¹, Vinod Chandran², Fawnda Pellett³, Remy Pollock⁴, Fatima Abji⁵, Adele Carty⁶, Sutharshini Shanmugarajah⁵, Cheryl Rosen⁷ and D. D. Gladman⁸, ¹Rheumatology, University of Toronto, Toronto Western Hospital, Toronto, ON, Canada, ²Centre for Prognosis Studies in the Rheumatic Diseases, Toronto Western Hospital and University of Toronto, Toronto, ON, Canada, ³Division of Rheumatology, University of Toronto, Toronto Western Hospital, Toronto, ON, Canada, ⁴Toronto Western Hospital and University of Toronto, Toronto, ON, Canada, ⁵Rheumatology, Toronto Western Hospital and University of Toronto, Toronto, ON, Canada, ⁶Rheumatology, Toronto Western Hospital, University of Toronto, Toronto, ON, Canada, ⁷Division of Dermatology, University of Toronto, Toronto western Hospital, Toronto, ON, Canada, ⁸Division of Rheumatology, Toronto Western Hospital and University of Toronto, Toronto, ON, Canada
Background/Purpose: Alpha7 nicotinic acetylcholine receptor (CHRNA7) is an ion channel that is gated by the binding of nicotinic ligands. Nicotine interacts with CHRNA7 leading to…
Abstract Number: 2223 • 2012 ACR/ARHP Annual Meeting
Dysregulation of Chromatin Modification Enzymes in Psoriatic Arthritis
Remy Pollock¹, Fawnda Pellett², Vinod Chandran³ and Dafna D. Gladman⁴, ¹University of Toronto, Toronto Western Hospital, Toronto, ON, Canada, ²Division of Rheumatology, University of Toronto, Toronto Western Hospital, Toronto, ON, Canada, ³Centre for Prognosis Studies in the Rheumatic Diseases, Toronto Western Hospital and University of Toronto, Toronto, ON, Canada, ⁴Division of Rheumatology, Toronto Western Hospital and University of Toronto, Toronto, ON, Canada
Background/Purpose: Chromatin modification enzymes regulate gene expression by altering the accessibility of promoters to transcription factors. Several of these enzymes are dysregulated in rheumatoid arthritis,…
Abstract Number: 108 • 2012 ACR/ARHP Annual Meeting
Disparity Between Sonographic and Clinical Criteria of Remission in Psoriasis Arthritis
Christian Dejaco¹, Rusmir Husic², Judith Gretler³, Winfried B. Graninger⁴ and Josef Hermann², ¹Rheumatology, Southend University Hospital, Westcliff-on-Sea, United Kingdom, ²Rheumatology, Medical University Graz, Graz, Austria, ³Med Univ Klinik Graz, Auenbruggerplatz 15, Graz, Austria, ⁴Internal medicine/Rheumatology and Immunology, Medical University Graz, Graz, Austria
Background/Purpose: To compare ultrasound and clinical definitions of remission in psoriasis arthritis (PsA). Methods: Prospective study of 70 consecutive PsA patients [mean age 51.1 (±SD…

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