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Abstracts tagged "Psoriatic arthritis"

  • Abstract Number: 930 • 2016 ACR/ARHP Annual Meeting

    How to Implement Cardiovascular Disease Risk Assessment for Patients with Inflammatory Joint Diseases in Daily Rheumatology Practice: An Overview of a Nationwide Norwegian Project

    Eirik Ikdahl1, Silvia Rollefstad2, Grunde Wibetoe3, Anne Salberg4, Dag Magnar Soldal5, Inge C Olsen6, Tore K Kvien6, Glenn Haugeberg7 and Anne Grete Semb1, 1Preventive Cardio-Rheuma clinic, Dept. of Rheumatology, Diakonhjemmet Hospital, Oslo, Norway, 2Preventive Cardio-Rheuma Clinic, Department of Rheumatology, Diakonhjemmet Hospital, Oslo, Norway, 3Rheumatology, Diakonhjemmet Hospital, Oslo, Norway, 4Hospital for Rheumatic Diseases, Lillehammer, Norway, 5Rheumatology, Hospital of Southern Norway, Kristiansand, Norway, 6Dept. of Rheumatology, Diakonhjemmet Hospital, Oslo, Norway, 7Martina Hansens Hospital, Bærum, Norway

    Background/Purpose:  The EULAR recommendations for cardiovascular disease (CVD) risk management in patients with inflammatory joint diseases (IJD) states that CVD risk assessment should be considered…
  • Abstract Number: 1713 • 2016 ACR/ARHP Annual Meeting

    Long-Term (156-Week) Safety Profile of Apremilast, an Oral Phosphodiesterase 4 Inhibitor, in Patients with Psoriatic Arthritis: Pooled Safety Analysis of 3 Phase III, Randomized, Controlled Trials

    Philip J Mease1, Dafna D Gladman2, Juan J Gomez-Reino3, Stephen Hall4, Arthur Kavanaugh5, Eric Lespessailles6, Georg Schett7, Kamal Shah8, Lichen Teng8 and Jürgen Wollenhaupt9, 1Swedish Medical Center and University of Washington School of Medicine, Seattle, WA, 2Toronto Western Research Institute, Toronto, ON, Canada, 3Hospital Clinico Universitario, Santiago, Spain, 4Monash University, CabriniHealth, Melbourne, Australia, 5University of California, San Diego, School of Medicine, La Jolla, CA, 6University of Orléans, Orléans, France, 7University of Erlangen-Nuremberg, Erlangen, Germany, 8Celgene Corporation, Summit, NJ, 9Schön Klinik Hamburg-Eilbek, Hamburg, Germany

    Background/Purpose: Apremilast (APR), an oral phosphodiesterase 4 inhibitor, acts to regulate immune activity in psoriatic arthritis (PsA) patients. PALACE 1 (NCT01172938), 2 (NCT01212757), and 3…
  • Abstract Number: 3085 • 2016 ACR/ARHP Annual Meeting

    Do Depression and Anxiety Reduce the Chance of Remission in Rheumatoid Arthritis and Psoriatic Arthritis?

    Brigitte Michelsen1,2, Karen M Fagerli1, Elisabeth Lie1, Hilde Berner Hammer3, Glenn Haugeberg4,5, Eirik K Kristianslund1 and Tore K. Kvien1, 1Dept. of Rheumatology, Diakonhjemmet Hospital, Oslo, Norway, 2Dept. of Rheumatology, Hospital of Southern Norway Trust, Kristiansand, Norway, 3Rheumatology, Diakonhjemmet Hospital, Oslo, Norway, 4Dept. of Rheumatology, Martina Hansens Hospital, Bærum, Norway, 5Dept. of Rheumatology, The Norwegian University of Science and Technology, Trondheim, Norway

    Background/Purpose: Depression and anxiety are reported to predict poorer treatment outcomes in rheumatoid arthritis (RA).1 Whether this can be confirmed in larger, prospective studies as…
  • Abstract Number: 938 • 2016 ACR/ARHP Annual Meeting

    Prevalence of Non-Radiographic Axial Spondyloarthritis in Psoriatic Arthritis – a Single Center Observational Study 

    Victoria Furer1, Moshe Stark2, Hagit Matz3, David Levartovsky4, Jonathan Wallman5, Irena Wigler6, Hagit Sarvagyl-Maman7, Ofir Elalouf8, Sara Borok Lev-Ran9, Daphna Paran6, Gideon Flusser10, Iddo Drukman10, Iris Eshed11 and Ori Elkayam12, 1Rheumatology, Tel Aviv Sourasky Medical Center, The Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel, 2Tel Aviv Medical Center, Tel Aviv, Tel Aviv, Israel, 3Dermatology, Tel Aviv Medical Center, Tel Aviv, Israel, 4Rheumatology, Tel-Aviv Sourasky Medical Center, Sackler Faculty of Medicine, Tel-Aviv University, Tel-Aviv, Israel, 5Rheumatology, Tel-Aviv Sourasky Medical Center, Tel-Aviv, Israel, 6Rheumatology, Tel Aviv Sourasky Medical Center and the Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel, 7Tel Aviv Sourasky Medical Center and the Sackler Faculty of Medicine, Tel Aviv University, Tel-aviv, Israel, 8Rheumatology, Tel Aviv Medical Center and the Sackler Faculty of Medicine, Tel Aviv University, Tel-Aviv, Israel, 9Tel Aviv Sourasky Medical Center and the Sackler Faculty of Medicine,Tel Aviv University, Tel AViv, Israel, 10Radiology, Tel Aviv Medical Center, Tel Aviv, Israel, 11Department of Radiology, Sheba Medical Center, Israel, Tel Hashomer, Israel, 12Rheumatology, Tel Aviv Medical Center, Tel Aviv, Israel

    Background/Purpose: Sacroiliitis, as detected by plain radiographs of the sacroiliac joints (SIJ), has been reported in a third of the psoriatic arthritis (PsA) population. (1)…
  • Abstract Number: 1722 • 2016 ACR/ARHP Annual Meeting

    Predictors of Achieving Remission Among Patients with Psoriatic Arthritis Prescribed TNF Inhibitors

    Alexis Ogdie1, J. Lynn Palmer2, Jeffrey D. Greenberg3, Leslie R. Harrold4, Daniel H. Solomon5, Arthur Kavanaugh6, Joel Kremer7, Philip J Mease8 and Jeffrey R. Curtis9, 1Medicine/Rheumatology and Epidemiology, University of Pennsylvania, Philadelphia, PA, 2Corrona Research Foundation, Albany, NY, 3New York University School of Medicine, New York, NY, 4University of Massachusetts Medical School, Worcester, MA, 5Division of Rheumatology, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, 6University of California San Diego, La Jolla, CA, 7The Center for Rheumatology, Albany Medical College, Albany, NY, 8Rheumatology and Internal Medicine, Swedish Medical Center and University of Washington, Seattle, WA, 9Division Clinical Immunology & Rheumatology, University of Alabama at Birmingham, Birmingham, AL

    Background/Purpose: Psoriatic arthritis (PsA) is a heterogeneous disease with varied response to therapy. We examined predictors of remission at one year among patients with PsA…
  • Abstract Number: 961 • 2016 ACR/ARHP Annual Meeting

    Secukinumab Provides Sustained Improvements in the Signs and Symptoms of Active Psoriatic Arthritis through 3 Years: Efficacy and Safety Results from a Phase 3 Trial

    Philip J Mease1, Arthur Kavanaugh2, Andreas Reimold3, Hasan Tahir4, Juergen Rech5, Stephen Hall6, Piet Geusens7,8, Pellet Pascale9, Evie Maria Delicha10, Luminita Pricop11 and Shephard Mpofu10, 1Swedish Medical Center and University of Washington, Seattle, WA, 2UC San Diego School of Medicine, La Jolla, CA, 3Dallas VA Medical Center and University of Texas Southwestern Medical Center, Dallas, TX, 4Barts Health NHS Trust, London, United Kingdom, 5Department of Internal Medicine 3 – Rheumatology and Immunology, Universitätsklinikum Erlangen, Friedrich-Alexander-University Erlangen-Nürnberg (FAU), Erlangen, Germany, 6Monash University, Melbourne, Australia, 7University of Hasselt, Hasselt, Belgium, 8Maastricht University Hospital, Maastricht, Netherlands, 9Novartis Pharma AG, basel, Switzerland, 10Novartis Pharma AG, Basel, Switzerland, 11Novartis Pharmaceuticals Corporation, East Hanover, NJ

    Background/Purpose:  Secukinumab, an anti–interleukin-17A monoclonal antibody, provided rapid and significant improvements in the key clinical domains of psoriatic arthritis (PsA) in the FUTURE 1 study…
  • Abstract Number: 1728 • 2016 ACR/ARHP Annual Meeting

    Comparison of Adherence to Disease Modifying Antirheumatic Drugs in Psoriatic Arthritis and Other Rheumatic Disease

    Mehmet Ali Balci1, Mustafa Ferhat Oksuz2, Salim Donmez1, Tugce Ozen3, Ediz Dalkilic2, Ayse Nur Tufan2, Yavuz Pehlivan2 and Omer Nuri Pamuk4, 1Rheumatology, Trakya University Medical Faculty, Edirne, Turkey, 2Rheumatology, Uludag University Medcal Faculty, Bursa, Turkey, 3PHYSICAL THERAPY AND REHABILITATION, Trakya University Faculty of Health Sciences, Edirne, Turkey, 4Rheumatology, Department of Rheumatology, Trakya University Medical Faculty, Edirne, Turkey, Edirne, Turkey

    Background/Purpose:  Psoriatic arthritis (PsA), Rheumatoid arthritis (RA) and ankylosing spondylitis (AS) are an inflammatory arthritis causing joint damage and disability. Non-adherence to disease modifying anti-rheumatic…
  • Abstract Number: 665 • 2015 ACR/ARHP Annual Meeting

    Construct Validity of Disease Activity for Psoriatic Arthritis Composite Index and Tentative Cut-Off Values in a Cohort of Patients with Psoriatic Arthritis

    Josefina Gallino Yanzi1, Emilce Schneeberger1, Osvaldo Luis Cerda1, Cecilia Zaffarana1, Margarita Landi1, Marcos G. Rosemffet2, Natalia Zamora3, Tomas Cazenave2, Fernando Dal Pra1, Paula Kohan4, Emilio Buschiazzo5 and Gustavo Citera2, 1Instituto de Rehabilitación Psicofísica, Buenos Aires, Argentina, 2Rheumatology, Instituto de Rehabilitación Psicofísica, Buenos Aires, Argentina, 3Reumatologia, Instituto de Rehabilitación Psicofísica, Buenos Aires, Argentina, 4Hospital Dr. E. Tornu, Buenos Aires, Argentina, 5Rheumatology, Hospital Sr Del Milagro, Salta, Argentina

    Background/Purpose: Disease Activity for Psoriatic Arthritis (DAPSA) is a composite index that assesses disease activity in patients with Psoriatic Arthritis (PsA) taking into account peripheral…
  • Abstract Number: 2864 • 2015 ACR/ARHP Annual Meeting

    Long-Term Work Productivity Improvement Associated with Apremilast, an Oral Phosphodiesterase 4 Inhibitor, in Patients with Psoriatic Arthritis: Pooled Analysis of 3 Phase 3 Studies

    Frank Zhang1, Zoe Clancy2 and Stan Li3, 1Pricing and Market Access, I&I, Celgene Corporation, Warren, NJ, 233 Technology Drive, Celgene Corporation, Warren, NJ, 3Celgene Corporation, Warren, NJ

    Background/Purpose: Studies have shown that patients with psoriatic arthritis (PsA) have significantly compromised physical health and quality of life, and negative effect on work productivity…
  • Abstract Number: 667 • 2015 ACR/ARHP Annual Meeting

    Comparison of Patient and Provider Assessments of Response to Therapy for Psoriatic Arthritis

    Tobee Gunter1 and Jessica Walsh2, 1Rheumatology, School of Medicine, University of Utah Internal Medicine, Salt Lake City, UT, 2Division of Rheumatology, Salt Lake City Veteran Affairs and University of Utah Medical Centers, Salt Lake City, UT

    Background/Purpose: Little is known about how psoriatic arthritis patients and their providers perceive response to therapy.  Discrepancies in perceptions of therapy response may indicate that…
  • Abstract Number: 2873 • 2015 ACR/ARHP Annual Meeting

    Pharmacological Treatment of Psoriatic Arthritis (PSA): Systematic Literature Review for the Update of the EULAR Recommendations for the Management of PSA

    Sofia Ramiro1, Josef S. Smolen2, Robert B.M. Landewé3, Désirée van der Heijde1, Maxime Dougados4, Paul Emery5, Maarten de Wit6, Maurizio Cutolo7, Susan Oliver8 and Laure Gossec9, 1Rheumatology, Leiden University Medical Center, Leiden, Netherlands, 2Department of Rheumatology, Medical University of Vienna, Vienna, Austria, 3Department of Rheumatology, Amsterdam Rheumatology Center, Amsterdam, Netherlands, 4Rheumatology Department, Cochin hospital, Paris-Descartes University, Paris, France, 5Section of Musculoskeletal Disease, Leeds Institute of Molecular Medicine, University of Leeds, Leeds, United Kingdom, 6EULAR Social Leagues, Zurich, Switzerland, 7Division of Clinical Immunology, Dept Internal Medicine, University of Genova, Genova, Italy, 8Independent Nurse Consultant, North Devon, United Kingdom, 9Rheumatology, Pitié Salpetriere Hospital, Paris, France

    Background/Purpose: As part of the update of the EULAR recommendations for the management of PsA, we performed a systematic literature review to assess the efficacy…
  • Abstract Number: 670 • 2015 ACR/ARHP Annual Meeting

    Evaluation of the Predictive Value of Non-Specific Musculoskeletal Symptoms in Preclinical Phases of Psoriatic Arthritis

    Lihi Eder1, Ari Polachek1, Cheryl Rosen2, Vinod Chandran1, Richard J. Cook3 and Dafna D. Gladman1, 1Rheumatology, University of Toronto, Toronto Western Hospital, Toronto, ON, Canada, 2Dermatology, University of Toronto, Toronto Western Hospital, Toronto, ON, Canada, 3Statistics and Actuarial Science, University of Waterloo, Waterloo, ON, Canada

    Background/Purpose: Limited information exists about the characteristics of pre-clinical phases of psoriatic arthritis (PsA). We aimed to assess whether the presence and trends in non-specific…
  • Abstract Number: 2874 • 2015 ACR/ARHP Annual Meeting

    Two-Years Survival of Golimumab in Patients with Rheumatoid Arthritis, Psoriatic Arthritis, and Axial Spondyloarthritis and Predictors Thereof in Real-Life Settings

    Leonardo Santo1, Angelo Semeraro2, Carmelo Zuccaro3, Maria Grazia Anelli4, Romano Bucci5, Antonio Marsico6, Laura Quarta7, Giorgio Carlino8, Francesco Paolo Cantatore9, Annamaria Gaudio10, Fabio Cacciapaglia11, Oriana Casilli12, Paola Chiara Francesca Falappone13 and Florenzo Iannone14, 1DSS4 Barletta, ASL BT Andria - Rheumatology Service, Barletta, Italy, 2Unità Operativa di Reumatologia ASL Taranto, Taranto, Italy, 3U.O.of Geriatrics, Outpatient clinic of Rheumatology, Brindisi, Italy, 4DIM, Rheumatology Unit, Bari, Italy, 5A.O.U., Rheumatology Hospital Unit, Foggia, Italy, 6Outpatient clinic of Rheumatology, Taranto,, Italy, 7Department of Rheumatology, "V.Fazzi" Hospital, San Cesario di Lecce, Italy, 8ASL LE - DSS Casarano and Gallipoli, Rheumatology Service, Gallipoli, Italy, 9Department of Rheumatology, University of Foggia,, Foggia, Italy, 10Department of Rheumatology, University of Foggia, Foggia, Italy, 11Internal Medicine Unit and Outpatient clinic of Rheumatology, “N. Melli” Hospital, San Pietro Vernotico (BR), Italy, 12Department of Rheumatology, "Vito Fazzi" Hospital, San Cesario di Lecce, Italy, 13Internal Medicine Unit - Outpatient clinic of Rheumatology,, "S. Camillo de' Lellis" Hospital, Mesagne (BR), Italy, 14Interdisciplinary Department of Medicine (DIM), Rheumatology Unit, University of Bari, Bari, Italy

    Background/Purpose: It has previously been shown that the survival of anti-TNF drugs was lower in Rheumatoid arthritis (RA) than in other chronic arthritis1. The objective…
  • Abstract Number: 675 • 2015 ACR/ARHP Annual Meeting

    Vitamin D Deficiency in Rheumatoid Arthritis, Ankylosing Spondylitis and Psoriatic Arthritis. Results of the CARMA Study

    Ana Urruticoechea1, Maria Auxiliadora Martin2, Santos Castañeda3, Carlos Alberto Sánchez-Piedra2, Carlos González-Juanatey4, Javier Llorca5, Federico Díaz-González6 and Miguel Angel Gonzalez-Gay7, 1Hospital Can Misses, Ibiza, Spain, 2Research Unit of Spanish Society of Rheumatology,, Madrid, Spain, 3Rheumatology, H.U. La Princesa, Madrid, Spain, 4Division or Cardiology, Hospital Lusus Augusti, Lugo, Spain, 5Department of Epidemiology and Computational Biology, School of Medicine, University of Cantabria, and CIBER Epidemiología y Salud Pública (CIBERESP), IDIVAL, Santander, Spain, 6Investigation Unit, Sociedad Española de Reumatológía, Madrid, Spain, 7Rheumatology, Hospital Universitario Marqués de Valdecilla. IDIVAL, Santander, Spain

    Background/Purpose: To study the association between 25-hydroxyvitamin D (25(OH)D) levels and the clinical characteristics of patients with chronic inflammatory rheumatic diseases (CIRD). Methods: Cross section…
  • Abstract Number: 2888 • 2015 ACR/ARHP Annual Meeting

    Apremilast, an Oral Phosphodiesterase 4 Inhibitor, Is Associated with Long-Term (104-Week) Improvements in Enthesitis and Dactylitis in Patients with Psoriatic Arthritis: Pooled Results from Three Phase III, Randomized, Controlled Trials

    Dafna D. Gladman1, Arthur Kavanaugh2, Adewale O. Adebajo3, Juan J. Gomez-Reino4, Jürgen Wollenhaupt5, Maurizio Cutolo6, Georg A. Schett7, Eric Lespessailles8, Melissa McIlraith9, ChiaChi Hu9, Christopher J. Edwards10, Charles A. Birbara11 and Philip J. Mease12, 1Toronto Western Hospital, Toronto, ON, Canada, 2University of California, San Diego School of Medicine, LaJolla, CA, 3University of Sheffield, Sheffield, United Kingdom, 4Hospital Clinico Universitario, Santiago, Spain, 5Schön Klinik Hamburg Eilbek, Hamburg, Germany, 6University of Genova, Genova, Italy, 7University of Erlangen-Nuremberg, Erlangen, Germany, 8University of Orléans, Orléans, France, 9Celgene Corporation, Warren, NJ, 10University Hospital Southampton, Southampton, United Kingdom, 11University of Massachusetts Medical School, Worcester, MA, 12Rheumatology Research, Swedish Medical Center, Seattle, WA

    Background/Purpose: Apremilast (APR), a PDE4 inhibitor, helps regulate immune responses in psoriatic arthritis (PsA). PALACE 1, 2, and 3 compared apremilast (APR) efficacy/safety with placebo…
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