ACR Meeting Abstracts

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Abstracts tagged "Psoriatic arthritis"

  • Abstract Number: 1469 • ACR Convergence 2024

    Manhattan Study: Observational, Ambispective Study to Describe Persistence and Effectiveness of a Second-line Guselkumab or TNF Inhibitors After First-line TNF Inhibitors for the Treatment of Active Psoriatic Arthritis in Spain

    María Rocío González Molina1, C Marín Huertas2, B Joven-Ibáñez3, L de Prado4, Lourdes Mateo5, M Llanes Gómez6, A Hernández del Río7, EA Blanco-Morales8, J Malavé Calzada9, Meritxell Sallés Lizarzaburu10, Inmaculada Ros-Vilamajó11, Martina Steiner12, EVELIN CERVANTES PEREZ13, Vanesa Hernández-Hernández14, S Castro Oreiro15, ANA URRUTICOECHEA16, L Orpinell Palacio17, J Campos Esteban18, Raúl Veroz González19, O Camacho Alcázar20, MP Moreno-Gil21, A Aragón Díez22, MJ Moreno-Ramos23, FJ Maceiras Pan24, S Díaz-Castroverde25, Santiago Muñoz Fernández26, JA Pinto Tasende27 and J Ramírez García28, 1Hospital Reina Sofía, Murcia, Murcia, Spain, 2Hospital Infanta Leonor, Madrid, Madrid, Spain, 3Hospital Universitario 12 de Octubre, Madrid, Madrid, Spain, 4Hospital de Mollet, Mollet del Vallès, Barcelona, Catalonia, Spain, 5H Germans Trias i Pujol, Barcelona, Spain, 6Hospital Juan Ramón Jiménez, Huelva, Andalucia, Spain, 7Hospital Naval, Ferrol, A Coruña, Galicia, Spain, 8Hospital Virgen del Rocío, Sevilla, Andalucia, Spain, 9Hospital Virgen del Puerto, Plasencia, Cáceres, Extremadura, Spain, 10Althaia Xarxa Assistencial Universitària Manresa, Manresa, Catalonia, Spain, 11Hospital Universitari Son Llàtzer, Palma de Mallorca, Islas Baleares, Spain, 12Department of Rheumatology. Hospital Universitario Infanta Sofía., Madrid, Spain, 13Complejo Hospitalario Universitario de Pontevedra, Pontevedra, Galicia, Spain, 14Hospital Universitario de Canarias, San Cristobal de La Laguna, Canarias, Spain, 15Hospital Sant Joan XXIII, Tarragona, Catalonia, Spain, 16Hospital Universitario Son Espases, Palma de Mallorca, Islas Baleares, Spain, 17Hospital Sagrat Cor, Barcelona, Spain, 18Hospital Universitario Puerta de Hierro Majadahonda, Madrid, Spain, 19Hospital Mérida, Badajoz, Spain, 20Hospital Sant Joan Despí Moisès Broggi, Sant Joan Despí, Barcelona, Catalonia, Spain, 21Hospital San Pedro de Alcántara, Cáceres, Extremadura, Spain, 22Hospital Universitario de Getafe, Getafe, Madrid, Madrid, Spain, 23Hospital Virgen de Arrixaca, Murcia, Murcia, Spain, 24Hospital de Meixoeiro, Pontevedra, Galicia, Spain, 25Johnson&Johnson Innovative Medicine, Madrid, Madrid, Spain, 26Hospital Universitario Infanta Sofía. Universidad Europea de Madrid, Madrid, Spain, 27Complejo Hospitalario Universitario, A Coruña, Spain, 28Hospital Clínic, Barcelona, Spain

    Background/Purpose: PsA is a complex inflammatory condition affecting both the skin and musculoskeletal system. Clinical guidelines recommend biological therapies after conventional synthetic DMARDs (csDMARDs) inadequate…
  • Abstract Number: 1912 • ACR Convergence 2024

    Greater Glucocorticoid and Less Biologic/Targeted Therapy Use in Midwest PsA Patients Despite Prevalent Comorbidity

    Brittany Banbury1, Sharon Dowell2, Christopher Jenkins3, Emily Holladay4, Cassie Clinton5, Fenglong Xie5, Jingyi Zhang5, Grace Wright6, Jeffrey Curtis7 and Gail Kerr8, 1Mount Sinai Beth Israel, Brooklyn, NY, 2NEA Baptist Memorial Hospital, JONESBORO, AR, 3Medstar Georgetown University Hospital, Washington, DC, 4University of Alabama at Birmingham, Edmond, OK, 5University of Alabama at Birmingham, Birmingham, AL, 6Grace C Wright MD PC, New York, NY, 7University of Alabama at Birmingham, Hoover, AL, 8Washington DC VAMC/Georgetown and Howard Universities, Washington, DC

    Background/Purpose: There is regional variation in the clinical characteristics, treatment, and outcomes of patients with inflammatory arthritis in the US. Despite a higher reported prevalence of…
  • Abstract Number: 2317 • ACR Convergence 2024

    Chronic Kidney Disease in Patients with Psoriatic Arthritis: A Cohort Study

    Fadi Kharouf1, Shangyi Gao2, Shahad Al-Matar3, Daniel Pereira4, Richard Cook5, Vinod Chandran6 and Dafna Gladman7, 1University Health Network and University of Toronto, Toronto, ON, Canada, Toronto, ON, Canada, 2Toronto Western Hospital, University of Toronto, Toronto, ON, Canada, 3Toronto Western Hospital, University of Toronto, Toronto, Canada, 4University Health Network, Toronto, ON, Canada, 5University of Waterloo, Waterloo, Canada, 6University of Toronto, Toronto, ON, Canada, 7University of Toronto, Toronto Western Hospital, Toronto, ON, Canada

    Background/Purpose: Chronic kidney disease (CKD) is a comorbidity in psoriatic arthritis (PsA). In this study, we aimed to define the prevalence of CKD in patients…
  • Abstract Number: 2334 • ACR Convergence 2024

    Characteristics of Patients with Psoriatic Arthritis Presenting with Axial Involvement: Results of a Prospective International Multicenter Study (AXIS)

    Murat Torgutalp1, Valderilio Azevedo2, Xenofon Baraliakos3, Filip Van den Bosch4, Jürgen Braun5, Alberto Cauli6, Laura Coates7, Vinod Chandran8, Torsten Diekhoff9, Floris van Gaalen10, Rodrigo Garcia Salinas11, Lianne S Gensler12, Niti Goel13, Alice Gottlieb14, Desiree van der Heijde15, Philip Helliwell16, Kay Geert Hermann17, Umut Kalyoncu18, Uta Kiltz19, Robert Lambert20, Ying Ying Leung21, Maria Llop22, Alejandra Lopez23, Miranda van Lunteren24, Ajesh Maharaj25, Walter Maksymowych26, Helena Marzo-Ortega27, Ashish J Mathew28, Philip Mease29, Peter Nash30, Mikkel Ostergaard31, Fabian Proft32, Mikhail Protopopov33, Sherry Rohekar34, RUXANDRA ELENA SCHIOTIS35, Joachim Sieper36, Enrique R. Soriano37, Lai-shan Tam38, James Wei39, Nelly Ziade40, Dafna Gladman41 and Denis Poddubnyy42, and AXIS Cohort Investigators, 1Charite Universitatsmedizin - Berlin, Berlin, Germany, 2Department of Internal Medicine, Universidade Federal of Paraná, Curitiba, Brazil, Curitiba, Brazil, 3Rheumazentrum Ruhrgebiet Herne, Ruhr-University Bochum, Herne, Germany, 4Ghent University Hospital, Ghent, Belgium, 5Rheumazentrum Ruhrgebiet Herne, Ruhr-University Bochum, Bochum, Germany., Herne, Germany, 6University of Cagliari, Cagliari, Italy, 7University of Oxford, Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, Oxford, United Kingdom, 8University of Toronto, Toronto, ON, Canada, 9Charite Universitatsmedizin Berlin, Berlin, Germany, 10LUMC, Leiden, Zuid-Holland, Netherlands, 11Hospital Italiano La Plata, La Plata, Argentina, 12Department of Medicine/Rheumatology, University of California, San Francisco, San Francisco, CA, 13Caduceus Biomedical Consulting, Duke University, Durham, NC, 14Department of Dermatology, Icahn School of Medicine, New York, NY, USA., New York, NY, 15Department of Rheumatology, Leiden University Medical Center, Meerssen, Netherlands, 16Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, Leeds, UK., Leeds, United Kingdom, 17Charite Medical School, Berlin, Germany, 18Hacettepe University, Faculty of Medicine, Department of Internal Medicine, Division of Rheumatology, Ankara, Turkey, 19Rheumazentrum Ruhrgebiet Herne, Ruhr-University, D-44649 Herne, Germany, 20University of Alberta, Edmonton, AB, Canada, 21Singapore General Hospital, Singapore, Singapore, 22Hospital Parc Tauli, Sabadell, Spain, 23Centro Dermatológico del Country, Guadalajara, Jalisco, Mexico, Guadalajara, Mexico, 24Leiden University Medical Center, Leiden, Zuid-Holland, Netherlands, 25Department of Internal Medicine & Therapeutics, Faculty of Health Sciences. Walter Sisulu University, Eastern Cape, South Africa, Eastern Cape, South Africa, 26Department of Medicine, University of Alberta, Edmonton, AB, Canada; CARE Arthritis, Edmonton, AB, Canada, Edmonton, Canada, 27NIHR Leeds BRC, Leeds Teaching Hospitals Trust and Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, Leeds, UK., Leeds, United Kingdom, 28Christian Medical College, Vellore, Tamil Nadu, India, 29Swedish Medical Center/Providence St. Joseph Health; University of Washington School of Medicine, Seattle, WA, 30School of Medicine, Griffith University, Sunshine Coast, Queensland, Australia, 31Department of Clinical Medicine, University of Copenhagen and Center for Rheumatology, Copenhagen Center for Arthritis Research, Glostrup, Denmark, 32Charité – Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany, 33Charite – Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany, 34Western University, London, Ontario, Canada, London, Canada, 35SPITAL CLINIC DE BOLI INFECTIOASE CLUJ NAPOCA, Cluj-Napoca, Romania, 36Charité University Medicine Berlin, Berlin, Germany, 37Hospital Italiano de Buenos Aires, Buenos Aires, Argentina, 38The Chinese University of Hong Kong, New Territories, Hong Kong, 39Chung Shan Medical University Hospital; China Medical University, Taichung, Taiwan (Republic of China), 40Saint-Joseph University, Beirut, Lebanon, 41University of Toronto, Toronto Western Hospital, Toronto, ON, Canada, 42Charite-Universitatsmedizin Berlin, Berlin, Germany

    Background/Purpose: Axial involvement, affecting the sacroiliac joints (SIJ) and/or spine, is a clinically relevant manifestation of psoriatic arthritis (PsA) that can influence management strategies. Previous…
  • Abstract Number: 2355 • ACR Convergence 2024

    Efficacy of Risankizumab Across Distinct PsA Phenotypes Identified with Machine Learning Analytics Using Data from Biologic DMARD-Naive Patients in Two Phase 3 Clinical Trials

    Laure Gossec1, Andra Balanescu2, Maria Antonietta D'Agostino3, Alexis Ogdie4, Philipp Sewerin5, Yu Deng6, Linyu Shi6, Yoshiyuki Sugimoto7, Sheng Zhong6, Yunzhao Xing6, Ralph Lippe6 and Mitsumasa Kishimoto8, 1Sorbonne Université, Paris, France, 2UNIVERSITY OF MEDICINE AND PHARMACY CAROL DAVILA, Bucharest, Romania, 3Versailles-Saint-Quentin University (INSERM U1173, Laboratoire d’Excellence INFLAMEX); University Hospital Ambroise Paré, Versailles, France, 4Department of Medicine, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, 5Rheumazentrum Ruhrgebiet, Ruhr University Bochum, Bochum, Germany, 6AbbVie Inc., North Chicago, IL, 7AbbVie GK, Tokyo, Tokyo, Japan, 8Department of Nephrology and Rheumatology, Kyorin University School of Medicine, Tokyo, Japan

    Background/Purpose: Risankizumab (RZB), an IL-23 p19 inhibitor, is well tolerated and provides long-term efficacy through 100 weeks in adults with PsA, demonstrated by the phase…
  • Abstract Number: 2635 • ACR Convergence 2024

    Direct to Patient Screening for Psoriatic Arthritis in Patients with Psoriasis: Appropriateness of Rheumatology Referrals and Treatment Outcomes

    Swetha Ann Alexander1, Shaobo Pei2, Gopi Penmetsa3, Soumya Reddy4, Jose Scher5, Alexis Ogdie6 and Jessica A Walsh7, 1University of Utah, Salt lake City, UT, 2University of Utah, Thousand Oaks, CA, 3University Of Utah Hospital, Salt Lake City, UT, 4NYU Grossman School of Medicine, New York, NY, 5New York University School of Medicine, New York, NY, 6Department of Medicine, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, 7Division of Rheumatology, Salt Lake City Veterans Affairs Health and University of Utah Health, Salt Lake City, UT

    Background/Purpose: Diagnostic delays in psoriatic arthritis (PsA) among psoriasis patients are common due to under recognition by referring providers. Previous studies show that a PsA…
  • Abstract Number: 0070 • ACR Convergence 2024

    Shared and Unique Fecal and Plasma Metabolic Signatures and Increased Inflammatory Markers in Ankylosing Spondylitis, Psoriatic Arthritis and Acute Anterior Uveitis

    Sneha Couvillion1, Javier Flores1, Sean Davin2, Kimberly Ogle2, Emma Fale-Olsen2, John Davis2, Gina Many1, Carley Shaut2, Tammy Martin2, Eric Suhler2, Atul Deodhar3, James Rosenbaum4, Ernesto Nakayasu1 and Tejpal Gill2, 1PNNL, Richland, WA, 2OHSU, Portland, OR, 3Division of Arthritis and Rheumatic Diseases, Oregon Health & Science University, Portland, OR, 4Corvus Pharmaceuticals and Legacy Devers Eye Institute, Portland, OR

    Background/Purpose: Spondyloarthritis (SpA) is a group of immune-mediated inflammatory disorders such as ankylosing spondylitis (AS) and psoriatic arthritis (PsA), along with acute anterior uveitis (AAU)…
  • Abstract Number: 0306 • ACR Convergence 2024

    Cardiovascular Risk Estimated with the New PREVENT Calculator and Disease Activity in Patients with Rheumatoid and Psoriatic Arthritis

    Aleydis Gonzalez Melendez1, Rebeca L. Polina-Lugo1, Maria F. Elizondo-Benitez2, Andrea Guajardo Aldaco1, Osvaldo Uresti3, Ricardo I. de la Rosa-Vazquez3, Iris Jazmín Colunga Pedraza1, Dionicio Galarza-Delgado4, jose Ramon Azpiri-Lopez5, Rosa Icela Arvizu-Rivera1 and Jesus Cardenas-de la Garza6, 1Division of Rheumatology, University Hospital "Dr. Jose Eleuterio Gonzalez", Universidad Autonoma de Nuevo Leon, Monterrey, Mexico, 2Division of Rheumatology, University Hospital "Dr. Jose Eleuterio Gonzalez", Universidad Autonoma de Nuevo Leon, Monterrey, Nuevo León, Mexico, 3Division of Rheumatology, University Hospital "Dr. Jose Eleuterio Gonzalez", Universidad Autonoma de Nuevo Leon, Monterrey, Nuevo León, Mexico, 4UANL Hospital Universitario, Monterrey, Nuevo León, Mexico, 5Division of Cardiology, University Hospital "Dr. Jose Eleuterio Gonzalez", Universidad Autonoma de Nuevo Leon, Monterrey, Mexico, 6Universidad Autónoma de Nuevo León, Monterrey, Nuevo León, Mexico

    Background/Purpose: The American Heart Association's PREVENT (Predicting Risk of Cardiovascular Disease EVENTs) is a new calculator developed in 2024, which estimates the 10- and 30-year…
  • Abstract Number: 0591 • ACR Convergence 2024

    Bimekizumab Maintained Efficacy Responses in Patients with Active Psoriatic Arthritis: Up to 2-Year Results from Two Phase 3 Studies

    Jessica A Walsh1, Joseph F. Merola2, Christopher T Ritchlin3, Yoshiya Tanaka4, Ennio Giulio Favalli5, Dennis McGonagle6, Diamant Thaçi7, Barbara Ink8, Rajan Bajracharya8, Jason Coarse9 and William Tillett10, 1Division of Rheumatology, Salt Lake City Veterans Affairs Health and University of Utah Health, Salt Lake City, UT, 2UT Southwestern Medical Center, Dallas, TX, 3Allergy, Immunology & Rheumatology Division, University of Rochester Medical School, Rochester, NY, 4Department of Internal Medicine, University of Occupational and Environmental Health, Kitakyushu, Fukuoka, Japan, 5ASST Gaetano Pini-CTO, Milan, Lombardia, Italy, 6National Institute for Health Research (NIHR) Leeds Biomedical Research Centre (BRC), Leeds Teaching Hospitals, Leeds, UK, Leeds, England, United Kingdom, 7Institute and Comprehensive Center for Inflammation Medicine, University of Lübeck, Lübeck, Schleswig-Holstein, Germany, 8UCB Pharma, Slough, United Kingdom, 9UCB Pharma, Morrisville, NC, 10Royal National Hospital of Rheumatic Diseases; Department of Life Sciences, Centre for Therapeutic Innovation, University of Bath, Bath, United Kingdom

    Background/Purpose: PsA is a chronic disease, and patients (pts) can experience loss of response with sustained therapy; therefore, assessing long-term maintenance of response in pts…
  • Abstract Number: 1011 • ACR Convergence 2024

    Use of the Shingrix Vaccine Among Patients with Inflammatory Arthritis and Risk of Cardiovascular Events Following Herpes Zoster

    Jeffrey Curtis1, Danielle M Conrad2, Whitney S Krueger2, Andrew P Gara2 and Kevin Winthrop3, 1FASTER Medicine, Hoover, AL, 2AbbVie, North Chicago, IL, 3School of Medicine, Oregon Health and Science University, Portland, OR

    Background/Purpose: The risk of herpes zoster (HZ) is increased in patients with inflammatory arthritis (IA); although the Shingrix vaccine has been available since 2017, its…
  • Abstract Number: 1433 • ACR Convergence 2024

    Association of Contextual Factors with Sonographic Inflammatory and Structural Phenotypes in Psoriatic Arthritis Patients

    Andre Lucas Ribeiro1, Sydney Thib2, Kangping Cui3, Sahil Koppikar4 and Lihi Eder5, 1Women's College Hospital & University of Toronto, Porto Alegre, Rio Grande do Sul, Brazil, 2Women's College Research Institute, Toronto, Canada, 3Sunnybrook Hospital, Toronto, Gravenhurst, ON, Canada, 4Women's College Hospital & University of Toronto, Toronto, ON, Canada, 5University of Toronto, Women’s College Hospital and Department of Medicine, Toronto, ON, Canada

    Background/Purpose: Ultrasound (US) is a valuable tool for enhancing disease activity assessment in psoriatic arthritis (PsA) by providing detailed visualization of both inflammatory and structural…
  • Abstract Number: 1470 • ACR Convergence 2024

    Patients with Psoriatic Arthritis from a Phase 4 Head-to-Head Study Stratified by Nail Involvement

    Alen Zabotti1, Alexis Ogdie2, Masato Okada3, Rebecca Bolce4, Jeffrey Lisse5, Marcus Ngantcha5, mohamed taher5, Khai Jing Ng6 and Dennis McGonagle7, 1Azienda Sanitaria Universitaria del Friuli Centrale, Udine, Udine, Italy, 2Department of Medicine, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, 3St. Luke's International Hospital, Tokyo, Japan, 4Eli Lilly and Company, Cincinnati, OH, 5Eli Lilly and Company, Indianapolis, IN, 6Eli Lilly and Company, Madrid, Spain, 7National Institute for Health Research (NIHR) Leeds Biomedical Research Centre (BRC), Leeds Teaching Hospitals, Leeds, UK, Leeds, England, United Kingdom

    Background/Purpose: Nails are a challenging body area to treat in patients (pts) with psoriatic arthritis (PsA)1. Previous research found that nail psoriasis is closely related…
  • Abstract Number: 1924 • ACR Convergence 2024

    Racial and Gender Disparities in Psoriatic Arthritis Clinical Trials

    Dania Kaur1, Fizza Zulfiqar2, Akshee Batra3 and Abhinav Vyas4, 1North Alabama Medical Center, Muscle Shoals, AL, 2Trinity Health Oakland/Wayne State University, Pontiac, MI, 3University of Miami, Miami, FL, 4Vanderbilt University Medical Center, Nahville, TN

    Background/Purpose: To develop effective novel treatment strategies for psoriatic arthritis that cater to patients from diverse backgrounds, it is crucial that all racial groups, without…
  • Abstract Number: 2318 • ACR Convergence 2024

    Does the Time Interval Between the Onset of Psoriasis and Psoriatic Arthritis Impact Disease Presentation and Outcomes?

    Fadi Kharouf1, Pankti Mehta2, Shangyi Gao2, Daniel Pereira3, Richard Cook4, Dafna Gladman5 and Vinod Chandran6, 1University Health Network and University of Toronto, Toronto, ON, Canada, Toronto, ON, Canada, 2Toronto Western Hospital, University of Toronto, Toronto, ON, Canada, 3University Health Network, Toronto, ON, Canada, 4University of Waterloo, Waterloo, Canada, 5University of Toronto, Toronto Western Hospital, Toronto, ON, Canada, 6University of Toronto, Toronto, ON, Canada

    Background/Purpose: Psoriasis typically precedes psoriatic arthritis (PsA), with a variable transition period. In this study, we aimed to explore whether the time interval between the…
  • Abstract Number: 2335 • ACR Convergence 2024

    Hand Function and Development of Psoriatic Arthritis in Skin Psoriasis Patients, a Prospective Cohort Study

    Birte Coppers1, Sara Bayat2, Koray Tascilar1, Daniela Bohr1, Larissa Valor1, David Simon3, Filippo Fagni1, Giulia Corte2, Axel Hueber4, Harriet Morf1, verena schönau1, Michael Sticherling5, eva manger1, sonja liehr1, Juergen Rech1, Georg Schett6, Arnd Kleyer7 and Anna-Maria Liphardt1, and Birte Coppers and Sara Bayat, 1Department of Internal Medicine 3 - Rheumatology and Immunology, Friedrich-Alexander University (FAU) Erlangen-Nürnberg and Universitätsklinikum Erlangen, Erlangen, Germany, Deutsches Zentrum für Immuntherapie (DZI), Friedrich Alexander University Erlangen-Nuremberg and Universitätsklinikum Erlangen, Erlangen, Germany, Erlangen, Germany, 2Department of Internal Medicine 3 - Rheumatology and Immunology, Friedrich-Alexander University (FAU) Erlangen-Nürnberg and Universitätsklinikum Erlangen, Erlangen, Germany, Deutsches Zentrum für Immuntherapie (DZI), Friedrich Alexander University Erlangen-Nuremberg and Universitätsklinikum Erlangen, Erlangen, Germany, Erlangen, Bayern, Germany, 3Charité - Universittsmedizin Berlin, Berlin, Germany, 4Klinikum Nuernberg, Nuernberg, Germany, 5FAU Erlangen-Nürnberg & Universitätsklinikum Erlangen, Department of Dermatology, Erlangen, Germany, Erlangen, Germany, 6Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany, 7Charité - Universittsmedizin Berlin, Erlangen, Germany

    Background/Purpose: Patients with skin psoriasis (Pso) have an increased risk of developing psoriatic arthritis (PsA) (6-42%) compared to the general population (0.02-0.42%) [1]. Early diagnosis…
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