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Abstracts tagged "Psoriatic arthritis"

  • Abstract Number: 1218 • ACR Convergence 2022

    Prevalence and Impact of Widespread Pain and Fibromyalgia on Measurement of Disease Severity in Psoriatic Arthritis: Lessons from the CorEvitas Registry

    Philip J Mease1, Alexis Ogdie2, Dimitrios Pappas3, George Reed4 and Joel Kremer5, 1Swedish Medical Center/Providence St. Joseph Health, Seattle, WA, 2Department of Medicine, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, 3CorEvitas, LLC, Waltham, MA, 4The Corrona Research Foundation and University of Massachusetts, Albany, NY, 5The Corrona Research Foundation, Delray Beach, FL

    Background/Purpose: Fibromyalgia (FM) occurs concomitantly with inflammatory rheumatic disease, including psoriatic arthritis (PsA), in up to 20% of patients and chronic widespread pain (CWP) in…
  • Abstract Number: 1496 • ACR Convergence 2022

    Do Patients in MDA Report Low Disease Activity Regardless of Which of the MDA Criteria Are Met?

    Sarah Yazji1, Philip Helliwell2, Andra Balanescu3, JUAN CANETE4, Emmanuelle Dernis5, Uta Kiltz6, Ying Ying Leung7, Ennio Lubrano8, Ana-Maria Orbai9, PENELOPE PALOMINOS10, Rossana Scrivo11, Josef Smolen12, Sandra Meisalu13, Maarten de Wit14, Laure Gossec15 and Laura Coates16, 1University of Oxford, Oxford, United Kingdom, 2Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, Leeds, United Kingdom, 3University of Medicine and Pharmacy Carol Davila, Bucharest, Romania, 4Rheumatology Department, Hospital Clinic and IDIBAPS, Barcelona, Spain, 5LE MANS general hospital, LE MANS, France, 6Rheumazentrum Ruhrgebiet, Herne, Germany, 7Rheumatology Department, Singapore General Hospital, Singapore, Singapore, 8Academic Rheumatology Unit, Dipartimento di Medicina e Scienze della Salute ‘‘Vincenzo Tiberio’’, Università degli Studi del Molise, Campobasso, Italy, 9Johns Hopkins University School of Medicine, Division of Rheumatology, Baltimore, MD, 10Hospital de Clinicas de Porto Alegre, Porto Alegre, Rio Grande do Sul, Brazil, 11Rheumatology Unit, Department of Clinical Internal, Anesthesiological and Cardiovascular Sciences, Sapienza University of Rome, Rome, Italy, Roma, Rome, Italy, 12Medical University of Vienna, Vienna, Austria, 13East Tallinn Central Hospital, Tallinn, Estonia, 14Patient research partner, Amsterdam, Netherlands, 15Sorbonne Université, Paris, France, 16Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, Oxford, UK, Oxford, England, United Kingdom

    Background/Purpose: The Minimal Disease Activity (MDA) criteria evaluate PsA disease activity and response to treatment and are defined as meeting ≥5 criteria: tender joint count…
  • Abstract Number: 1601 • ACR Convergence 2022

    Female Psoriatic Arthritis Patients Show Differences in Treatment Response to IL12/23 Inhibition in Combination with or Without MTX Compared to Male – Results from a Multicenter Investigator-initiated Randomized Placebo-controlled Clinical Trial

    Michaela Koehm1, Ann Christina Foldenauer2, Tanja Rossmanith3, Herbert Kellner4, Uta Kiltz5, Juergen Rech6, Gerd Burmester7, David Kofler8, Jan Brandt-Juergens9, Stephanie Finzel10, Raoul Bergner11, Maren Sieburg12 and Frank Behrens13, 1Rheumatology Goethe-University Frankfurt, Frankfurt Am Main, Germany, 2Fraunhofer Institute for Translational Medicine and Pharmacology ITMP, Frankfurt, 3Fraunhofer Institute for Translational Medicine & Pharmacology ITMP, Frankfurt, Germany, 4Schwerpunktpraxis für Rheumatologie und Gastroenterologie, Munich, Germany, 5Rheumazentrum Ruhrgebiet, Herne, Germany, 6University Clinic Erlangen, Erlangen, Germany, 7Charité University Medicine Berlin, Berlin, Germany, 8University of Cologne, Cologne, Germany, 9Rheumatologische Schwerpunktpraxis, Berlin, Germany, 10University of Freiburg, Freiburg, Germany, 11Klinikum Ludwigshafen, Ludwigshafen, Germany, 12Rheumatologische Facharztpraxis, Magdeburg, Germany, 13Rheumatology University Hospital & Fraunhofer Institute Translational Medicine and Pharmacology, Goethe-University Frankfurt, Frankfurt Am Main, Germany

    Background/Purpose: Subgroup analysis from different clinical trials and real-world data suggest, that there are differences in baseline characteristics, clinical phenotypes, and treatment responses in female…
  • Abstract Number: 2112 • ACR Convergence 2022

    Stringent Disease Activity Control at 2 Years Across Psoriatic Arthritis Domains Irrespective of Baseline Characteristics in Patients Treated with Guselkumab: Post Hoc Analysis of a Phase 3, Randomized, Double-blind, Placebo-controlled Study

    Christopher Ritchlin1, Philip J Mease2, Wolf-Henning Boehncke3, John Tesser4, Soumya Chakravarty5, Emmanouil Rampakakis6, May Shawi7, Elena Schiopu8, Joseph Merola9, Iain B McInnes10 and Atul Deodhar11, 1Allergy, Immunology and Rheumatology Division, University of Rochester Medical School, Canandaigua, NY, 2Swedish Medical Center/Providence St. Joseph Health, Seattle, WA, 3Deptartment of Dermatology, Geneva University Hospitals, University of Geneva, Geneva, Switzerland, 4Arizona Arthritis & Rheumatology Associates, Phoenix, AZ, 5Janssen Scientific Affairs, LLC; Drexel University College of Medicine, Villanova, PA, 6McGill University, Department of Pediatrics and JSS Medical Research, Montréal, QC, Canada, 7Immunology Global Medical Affairs, Janssen Pharmaceutical Companies of Johnson & Johnson, Horsham, PA, 8Michigan Medicine Rheumatology Clinic – Taubman Center, Ann Arbor, MI, 9Brigham and Women's Hospital, Harvard Medical School, Boston, MA, 10Institute of Infection, Immunity and Inflammation, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, Scotland, United Kingdom, 11Oregon Health & Science University, Portland, OR, USA, Portland, OR

    Background/Purpose: Guselkumab (GUS) is associated with robust and sustained improvement in PsA signs and symptoms in subgroups of patients (pts) pooled from the phase 3…
  • Abstract Number: 2128 • ACR Convergence 2022

    Consistent Long-Term Guselkumab Efficacy Across Psoriatic Arthritis Domains Irrespective of Baseline Patient Characteristics

    Iain B McInnes1, John Tesser2, Elena Schiopu3, Joseph Merola4, Soumya Chakravarty5, Emmanouil Rampakakis6, Natalie Shiff7, Alexa Kollmeier8, Xie L Xu9, May Shawi10, Frederic Lavie11, Paul Bird12 and Philip J Mease13, 1Institute of Infection, Immunity and Inflammation, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, Scotland, United Kingdom, 2Arizona Arthritis & Rheumatology Associates, Phoenix, AZ, 3Michigan Medicine Rheumatology Clinic – Taubman Center, Ann Arbor, MI, 4Brigham and Women's Hospital, Harvard Medical School, Boston, MA, 5Janssen Scientific Affairs, LLC; Drexel University College of Medicine, Villanova, PA, 6McGill University, Department of Pediatrics and JSS Medical Research, Montréal, QC, Canada, 7Janssen Scientific Affairs, LLC; Community Health and Epidemiology, University of Saskatchewan, Philadelphia, PA, 8Janssen-Cilag, Research & Development, LLC, San Diego, CA, 9Janssen Research & Development, LLC, San Diego, CA, USA, San Marcos, CA, 10Immunology Global Medical Affairs, Janssen Pharmaceutical Companies of Johnson & Johnson, Horsham, PA, 11The Janssen Pharmaceutical Companies of Johnson & Johnson, Paris, France, Paris, France, 12University of New South Wales, Sydney, Australia, 13Swedish Medical Center/Providence St. Joseph Health, Seattle, WA

    Background/Purpose: In the phase 3 DISCOVER (D)-1 and D-2 studies, guselkumab (GUS) significantly improved joint symptoms, skin disease, enthesitis, dactylitis, physical function, and quality of…
  • Abstract Number: 2145 • ACR Convergence 2022

    Efficacy and Safety of Risankizumab for Active Psoriatic Arthritis: 100-Week Results from the KEEPsAKE 1 and KEEPsAKE 2 Trials

    Lars Erik1, Kim Papp2, Douglas White3, Cecilia Asnal4, Wenjing Lu5, Ahmed Soliman5, Byron Padilla6, Michael Chen5 and Andrew Ostor7, 1Bispebjerg-Frederiksberg Hospital, Vedbæk, Denmark, 2K Papp Clinical Research and Probity Medical Research, Waterloo, ON, Canada, 3Rheumatology Department, Waikato Hospital, and Waikato Clinical School, University of Auckland, Hamilton, New Zealand, 4Hospital Alemán, Buenos Aires, Argentina, 5AbbVie, Inc., North Chicago, IL, 6AbbVie, Inc., Waukegan, IL, 7Cabrini Hospital, Monash University & Emeritus Research, Melbourne, Australia

    Background/Purpose: PsA is a chronic, systemic inflammatory disease with a variety of clinical manifestations including arthritis, enthesitis, and dactylitis and is associated with skin and…
  • Abstract Number: 0192 • ACR Convergence 2022

    Upadacitinib versus Adalimumab on Routine Assessment of Patient Index Data 3 (RAPID3) in Patients with Psoriatic Arthritis

    Laura Coates1, Arthur Kavanaugh2, Erin McDearmon-Blondell3, Arthur Mandelin4, Tianming Gao5 and William Tillett6, 1Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, Oxford, UK, Oxford, England, United Kingdom, 2University of California San Diego, La Jolla, CA, 3AbbVie, Inc., Mettawa, IL, 4Northwestern University Feinberg School of Medicine, Chicago, IL, 5AbbVie, Inc., North Chicago, IL, 6Royal National Hospital for Rheumatic Diseases, Bath, United Kingdom

    Background/Purpose: RAPID3 (Routine Assessment of Patient Index Data 3) is a dis­ease activity index calculated from 3 patient-reported measures: phys­ical function, pain, and patient global…
  • Abstract Number: 0401 • ACR Convergence 2022

    Direct to Patient Screening of Psoriatic Arthritis: Clinical Findings and Outcomes of Patient-Driven Rheumatology Referrals

    Megan Meier1 and Jessica Walsh2, 1University of Utah, North Salt Lake, UT, 2University of Utah, Salt Lake City, UT

    Background/Purpose: Diagnostic delays are common with psoriatic arthritis (PsA), and screening surveys for identifying at-risk patients are infrequently used in busy clinical practices. We previously…
  • Abstract Number: 1007 • ACR Convergence 2022

    Metabolic Disorders and Abnormal Dietary Patterns and Their Association with Psoriatic Arthritis Activity: The Dietary Intervention in PsA (DIPSA) Study

    Lihi Eder1, Charlene Compher2, Helen Emanoilidis3, Ryan F. Quinn2, Dafna Gladman4, Vinod Chandran5, Jose Scher6 and Alexis Ogdie7, 1Women’s College Research Institute, Department of Medicine, University of Toronto, Toronto, ON, Canada, 2University of Pennsylvania, Philadelphia, PA, 3Women's College Hospital, Toronto, ON, Canada, 4Toronto Western Hospital, Schroeder Arthritis Institute, Toronto, ON, Canada, 5Departments of Medicine and Laboratory Medicine and Pathobiology, University of Toronto/ Schroeder Arthritis Institute, Krembil Research Institute, University Health Network, Toronto, ON, Canada, 6New York University School of Medicine, New York, NY, 7Department of Medicine, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA

    Background/Purpose: Psoriatic Arthritis (PsA) is associated with obesity and its related metabolic abnormalities. The role of diet as an adjunct therapy in PsA remains unclear.…
  • Abstract Number: 1038 • ACR Convergence 2022

    Genetic and Molecular Distinctions Between Axial Psoriatic Arthritis and Ankylosing Spondylitis

    Arthur Kavanaugh1, Xenofon Baraliakos2, Sheng Gao3, Warner Chen3, Kristen Sweet3, Soumya Chakravarty4, Qingxuan Song3, May Shawi5, Frank Behrens6 and Proton Rahman7, 1University of California San Diego, San Diego, CA, USA, San Diego, CA, 2Rheumazentrum Ruhrgebiet Herne, Herne, Germany, 3Janssen Research and Development, LLC, Spring House, PA, 4Janssen Scientific Affairs, LLC; Drexel University College of Medicine, Villanova, PA, 5Immunology Global Medical Affairs, Janssen Pharmaceutical Companies of Johnson & Johnson, Horsham, PA, 6Rheumatology University Hospital & Fraunhofer Institute Translational Medicine and Pharmacology, Goethe-University Frankfurt, Frankfurt Am Main, Germany, 7Memorial University, St. John's, NL, Canada

    Background/Purpose: Despite overlapping symptoms, axial psoriatic arthritis (axPsA) and ankylosing spondylitis (AS) may be distinct disorders with differing clinical manifestations, genetic associations, and radiographic findings.1…
  • Abstract Number: 1234 • ACR Convergence 2022

    Characterizing Imaging Phenotypes in PsA: The Effect of Age and Sex

    Lihi Eder1 and Kangping Cui2, 1Women’s College Research Institute, Department of Medicine, University of Toronto, Toronto, ON, Canada, 2University of Toronto, Toronto, ON, Canada

    Background/Purpose: Musculoskeletal ultrasound (MSK-US) provides valuable information on disease phenotype in psoriatic arthritis (PsA). While age and sex are important determinants of health, limited information…
  • Abstract Number: 1497 • ACR Convergence 2022

    How Does Time to Diagnosis and Gender Affect Treatment Outcomes in Patients with Ankylosing Spondylitis or Psoriatic Arthritis? – Real World Data from a German Observational Study with Secukinumab

    Karolina Benesova1, Oliver Hansen2, Uta Kiltz3, Jan Brandt-Juergens4, Peter Kästner5, Elke Riechers6, Daniel Peterlik7, Christina Budden7, Annika Boas7, Stefanie Welle7 and Hans-Peter Tony8, 1University Hospital Heidelberg, Heidelberg, Germany, 2Medizinische Abteilung V - Rheumatologie, Universitätsklinikum, Heidelberg, Germany, 3Rheumazentrum Ruhrgebiet, Herne, Germany, 4Rheumatologische Schwerpunktpraxis, Berlin, Germany, 5Ambulantes Rheumazentrum, Medizinisches Versorgungszentrum, Erfurt, Germany, 6Medizinische Hochschule Hannover, Hannover, Germany, 7Novartis Pharma GmbH, Nürnberg, Germany, 8Medizinische Klinik II - Rheumatologie/Immunologie, Universitätsklinikum Würzburg, Würzburg, Germany

    Background/Purpose: In both, ankylosing spondylitis (AS) and psoriatic arthritis (PsA), women typically have a longer delay in diagnosis.1,2 There is scientific evidence that prognosis for…
  • Abstract Number: 1602 • ACR Convergence 2022

    Fibroblast Activation Protein (FAP) PET-CT for Depicting Inflammatory Joint Damage in Patients with Psoriatic Arthritis

    Simon Rauber1, Hashem Mohammadian2, Chrstian Schmidkonz3, Armin Atzinger3, Maria Gabriella Raimondo1, Hannah Labinsky4, Christoph Treutlein2, Johannes Knitza1, Simone Maschauer2, Frank Roemer5, Olaf Prante2, Torsten Kuwert3, Juan Canete6, Georg Schett7 and Andreas Ramming1, 1Department of Internal Medicine 3 – Rheumatology and Immunology, Friedrich-Alexander-University Erlangen-Nürnberg and Universitätsklinikum Erlangen, 91054 Erlangen, Germany; Deutsches Zentrum Immuntherapie, Friedrich-Alexander-UniversityErlangen-Nürnberg and Universitätsklinikum Erlangen, Erlangen, Germany, 2Friedrich-Alexander-University (FAU) Erlangen-Nürnberg, Erlangen, Germany, 3Friedrich-Alexander University (FAU) Erlangen-Nuremberg, Erlangen, Germany, 4Department of Internal Medicine 3 - Rheumatology and Immunology, Friedrich-Alexander-University Erlangen-Nürnberg and Universitätsklinikum Erlangen, 91054 Erlangen, Germany; Deutsches Zentrum Immuntherapie, Friedrich-Alexander-University Erlangen-Nürnberg and Universitätsklinikum Erlangen, Erlangen, Germany, 5Friedrich-Alexander University Erlangen Nürnberg, Erlangen, Germany, 6Unidad de Artritis Hospital Clinic, Barcelona, Spain, 7Universitätsklinikum Erlangen, Erlangen, Germany

    Background/Purpose: Psoriatic arthritis (PsA) is characterized by substantial mesenchymal tissue activation in the context of inflammation leading to structural damage. Measuring mesenchymal tissue activation in…
  • Abstract Number: 2113 • ACR Convergence 2022

    Improvement in Key PsA Core Domains with Guselkumab Treatment in an Enriched Population of ACR20 Non-Responders at Week 24: Post Hoc Analysis of Two Phase 3 Studies

    Dennis McGonagle1, Derek Haaland2, Philip Helliwell3, A. Marilise Marrache4, May Shawi5, Emmanouil Rampakakis6, Peter Nash7, Fedra Irazoque Palazuelos8 and Arthur Kavanaugh9, 1Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds; National Institute for Health Research, Leeds Biomedical Research Centre, Leeds Teaching Hospitals NHS Trust, Leeds, United Kingdom, 2The Waterside Clinic, Oro Medonte, ON, Canada, 3Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, Leeds, United Kingdom, 4Janssen Inc., Dollard-des-Ormeaux, QC, Canada, 5Immunology Global Medical Affairs, Janssen Pharmaceutical Companies of Johnson & Johnson, Horsham, PA, 6McGill University, Department of Pediatrics and JSS Medical Research, Montréal, QC, Canada, 7School of Medicine, Griffith University, Sunshine Coast, Australia, 8Angeles Mocel Hospital; Universidad Autónoma de México, Ciudad de México, Mexico, 9University of California San Diego, La Jolla, CA

    Background/Purpose: Despite available PsA treatments, a portion of PsA patients (pts) does not achieve improvements in PsA signs and symptoms according to ACR response criteria.…
  • Abstract Number: 2130 • ACR Convergence 2022

    Apremilast in Bio-Naïve Patients with Early Psoriatic Arthritis: A National, Real-Life, Multicenter, Non-Interventional, Prospective, 52-week Cohort Study

    Petros P. Sfikakis1, Dimitrios Vassilopoulos2, Gkikas Katsifis3, Georgios Vosvotekas4, Theodoros Dimitroulas5, Argyro Repa6, Grigorios Sakellariou7, THEODORA SIMOPOULOU8, Athanasios Georgountzos9, Andreas Bounas10, Panagiotis Georgiou11, Evangelia Mole12, Evangelia Kataxaki13, Stamatis Nick Liossis14, Evangelos Theodorou15, Christina Antoniadou16, EVANGELOS THEOTIKOS17, PANAYIOTIS VLACHOYIANNOPOULOS18, THEODORA MARKATSELI19, Angeliki Kekki20, NIKOLAOS ANTONAKOPOULOS21 and Dimitrios Boumpas22, 1Joint Academic Rheumatology Program, National and Kapodistrian University of Athens, School of Medicine, Athens, Greece, 2Clinical Immunology-Rheumatology Unit, 2nd Department of Internal Medicine and Laboratory, National and Kapodistrian University of Athens, School of Medicine, Hippokration General Hospital, Athens, Greece, 3Naval Hospital of Athens, Athens, Greece, 4Euromedica General Clinic of Thessaloniki, Thessaloniki, Greece, Thessaloniki, Greece, 54th Department of Internal medicine, Hippokration Hospital, School of medicine, Aristotle University of Thessaloniki, Thessaloniki, Greece, Thessaloniki, Greece, 6Rheumatology, Clinical Immunology and Allergy, University of Crete School of Medicine, Heraklion, Crete, Greece, 7Department of Rheumatology, 424 General Army Hospital, Thessaloniki, Greece, Thessaloniki, Greece, 8Clinic of Rheumatology and Clinical Immunology, University Hospital of Larissa, Larissa, Greece, Larissa, Larisa, Greece, 9General Hospital of Athens G. Gennimatas, Athens, Greece, 10Olympion private General Clinic of Patras, Patras, Greece;, Patra, Akhaia, Greece, 11Rheumatology Unit, Agios Andreas Hospital, Patras, Greece, PATRA, Akhaia, Greece, 12Department of Rheumatology, KAT General Hospital of Attica, Athens, Greece, 13Rheumatology Unit, Thriasio General Hospital of Elefsina, Magoula, Greece, 14Division of Rheumatology, Department of Internal Medicine, Patras University Hospital, University of Patras Medical School, Patras, Greece, Patras, Akhaia, Greece, 15Rheumatology Clinic 251 Hellenic Air Force Hospital, Athens, Greece, 16First Department of Internal Medicine, University Hospital of Alexandroupolis, Democritus University of Thrace, Alexandroupolis, Greece, 17Rheumatology Department, Asklepieion Voulas General Hospital, Athens, Greece, 18Department of Pathophysiology, Medical School, National and Kapodistrian University of Athens, Athens, Greece, 19Rheumatology Clinic, Department of Internal Medicine, Medical School, University of Ioannina, Ioannina, Greece, 20Genesis Pharma SA, Halandri, Greece, 21Genesis Pharma SA, Chalandri, Greece, 224th Department of Internal Medicine, "Attikon" University Hospital, Athens, Joint Academic Rheumatology Program, Medical School, National and Kapodistrian University of Athens, Athens, Greece

    Background/Purpose: Apremilast is a targeted synthetic disease-modifying anti-rheumatic drug (tsDMARD) approved for psoriatic arthritis (PsA). Few clinical studies assessing treatment regimens in PsA have focused…
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All abstracts accepted to ACR Convergence are under media embargo once the ACR has notified presenters of their abstract’s acceptance. They may be presented at other meetings or published as manuscripts after this time but should not be discussed in non-scholarly venues or outlets. The following embargo policies are strictly enforced by the ACR.

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