ACR Meeting Abstracts

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Abstracts tagged "Psoriatic arthritis"

  • Abstract Number: 0401 • ACR Convergence 2022

    Direct to Patient Screening of Psoriatic Arthritis: Clinical Findings and Outcomes of Patient-Driven Rheumatology Referrals

    Megan Meier1 and Jessica Walsh2, 1University of Utah, North Salt Lake, UT, 2University of Utah, Salt Lake City, UT

    Background/Purpose: Diagnostic delays are common with psoriatic arthritis (PsA), and screening surveys for identifying at-risk patients are infrequently used in busy clinical practices. We previously…
  • Abstract Number: 1007 • ACR Convergence 2022

    Metabolic Disorders and Abnormal Dietary Patterns and Their Association with Psoriatic Arthritis Activity: The Dietary Intervention in PsA (DIPSA) Study

    Lihi Eder1, Charlene Compher2, Helen Emanoilidis3, Ryan F. Quinn2, Dafna Gladman4, Vinod Chandran5, Jose Scher6 and Alexis Ogdie7, 1Women’s College Research Institute, Department of Medicine, University of Toronto, Toronto, ON, Canada, 2University of Pennsylvania, Philadelphia, PA, 3Women's College Hospital, Toronto, ON, Canada, 4Toronto Western Hospital, Schroeder Arthritis Institute, Toronto, ON, Canada, 5Departments of Medicine and Laboratory Medicine and Pathobiology, University of Toronto/ Schroeder Arthritis Institute, Krembil Research Institute, University Health Network, Toronto, ON, Canada, 6New York University School of Medicine, New York, NY, 7Department of Medicine, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA

    Background/Purpose: Psoriatic Arthritis (PsA) is associated with obesity and its related metabolic abnormalities. The role of diet as an adjunct therapy in PsA remains unclear.…
  • Abstract Number: 1038 • ACR Convergence 2022

    Genetic and Molecular Distinctions Between Axial Psoriatic Arthritis and Ankylosing Spondylitis

    Arthur Kavanaugh1, Xenofon Baraliakos2, Sheng Gao3, Warner Chen3, Kristen Sweet3, Soumya Chakravarty4, Qingxuan Song3, May Shawi5, Frank Behrens6 and Proton Rahman7, 1University of California San Diego, San Diego, CA, USA, San Diego, CA, 2Rheumazentrum Ruhrgebiet Herne, Herne, Germany, 3Janssen Research and Development, LLC, Spring House, PA, 4Janssen Scientific Affairs, LLC; Drexel University College of Medicine, Villanova, PA, 5Immunology Global Medical Affairs, Janssen Pharmaceutical Companies of Johnson & Johnson, Horsham, PA, 6Rheumatology University Hospital & Fraunhofer Institute Translational Medicine and Pharmacology, Goethe-University Frankfurt, Frankfurt Am Main, Germany, 7Memorial University, St. John's, NL, Canada

    Background/Purpose: Despite overlapping symptoms, axial psoriatic arthritis (axPsA) and ankylosing spondylitis (AS) may be distinct disorders with differing clinical manifestations, genetic associations, and radiographic findings.1…
  • Abstract Number: 1234 • ACR Convergence 2022

    Characterizing Imaging Phenotypes in PsA: The Effect of Age and Sex

    Lihi Eder1 and Kangping Cui2, 1Women’s College Research Institute, Department of Medicine, University of Toronto, Toronto, ON, Canada, 2University of Toronto, Toronto, ON, Canada

    Background/Purpose: Musculoskeletal ultrasound (MSK-US) provides valuable information on disease phenotype in psoriatic arthritis (PsA). While age and sex are important determinants of health, limited information…
  • Abstract Number: 1497 • ACR Convergence 2022

    How Does Time to Diagnosis and Gender Affect Treatment Outcomes in Patients with Ankylosing Spondylitis or Psoriatic Arthritis? – Real World Data from a German Observational Study with Secukinumab

    Karolina Benesova1, Oliver Hansen2, Uta Kiltz3, Jan Brandt-Juergens4, Peter Kästner5, Elke Riechers6, Daniel Peterlik7, Christina Budden7, Annika Boas7, Stefanie Welle7 and Hans-Peter Tony8, 1University Hospital Heidelberg, Heidelberg, Germany, 2Medizinische Abteilung V - Rheumatologie, Universitätsklinikum, Heidelberg, Germany, 3Rheumazentrum Ruhrgebiet, Herne, Germany, 4Rheumatologische Schwerpunktpraxis, Berlin, Germany, 5Ambulantes Rheumazentrum, Medizinisches Versorgungszentrum, Erfurt, Germany, 6Medizinische Hochschule Hannover, Hannover, Germany, 7Novartis Pharma GmbH, Nürnberg, Germany, 8Medizinische Klinik II - Rheumatologie/Immunologie, Universitätsklinikum Würzburg, Würzburg, Germany

    Background/Purpose: In both, ankylosing spondylitis (AS) and psoriatic arthritis (PsA), women typically have a longer delay in diagnosis.1,2 There is scientific evidence that prognosis for…
  • Abstract Number: 1602 • ACR Convergence 2022

    Fibroblast Activation Protein (FAP) PET-CT for Depicting Inflammatory Joint Damage in Patients with Psoriatic Arthritis

    Simon Rauber1, Hashem Mohammadian2, Chrstian Schmidkonz3, Armin Atzinger3, Maria Gabriella Raimondo1, Hannah Labinsky4, Christoph Treutlein2, Johannes Knitza1, Simone Maschauer2, Frank Roemer5, Olaf Prante2, Torsten Kuwert3, Juan Canete6, Georg Schett7 and Andreas Ramming1, 1Department of Internal Medicine 3 – Rheumatology and Immunology, Friedrich-Alexander-University Erlangen-Nürnberg and Universitätsklinikum Erlangen, 91054 Erlangen, Germany; Deutsches Zentrum Immuntherapie, Friedrich-Alexander-UniversityErlangen-Nürnberg and Universitätsklinikum Erlangen, Erlangen, Germany, 2Friedrich-Alexander-University (FAU) Erlangen-Nürnberg, Erlangen, Germany, 3Friedrich-Alexander University (FAU) Erlangen-Nuremberg, Erlangen, Germany, 4Department of Internal Medicine 3 - Rheumatology and Immunology, Friedrich-Alexander-University Erlangen-Nürnberg and Universitätsklinikum Erlangen, 91054 Erlangen, Germany; Deutsches Zentrum Immuntherapie, Friedrich-Alexander-University Erlangen-Nürnberg and Universitätsklinikum Erlangen, Erlangen, Germany, 5Friedrich-Alexander University Erlangen Nürnberg, Erlangen, Germany, 6Unidad de Artritis Hospital Clinic, Barcelona, Spain, 7Universitätsklinikum Erlangen, Erlangen, Germany

    Background/Purpose: Psoriatic arthritis (PsA) is characterized by substantial mesenchymal tissue activation in the context of inflammation leading to structural damage. Measuring mesenchymal tissue activation in…
  • Abstract Number: 2113 • ACR Convergence 2022

    Improvement in Key PsA Core Domains with Guselkumab Treatment in an Enriched Population of ACR20 Non-Responders at Week 24: Post Hoc Analysis of Two Phase 3 Studies

    Dennis McGonagle1, Derek Haaland2, Philip Helliwell3, A. Marilise Marrache4, May Shawi5, Emmanouil Rampakakis6, Peter Nash7, Fedra Irazoque Palazuelos8 and Arthur Kavanaugh9, 1Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds; National Institute for Health Research, Leeds Biomedical Research Centre, Leeds Teaching Hospitals NHS Trust, Leeds, United Kingdom, 2The Waterside Clinic, Oro Medonte, ON, Canada, 3Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, Leeds, United Kingdom, 4Janssen Inc., Dollard-des-Ormeaux, QC, Canada, 5Immunology Global Medical Affairs, Janssen Pharmaceutical Companies of Johnson & Johnson, Horsham, PA, 6McGill University, Department of Pediatrics and JSS Medical Research, Montréal, QC, Canada, 7School of Medicine, Griffith University, Sunshine Coast, Australia, 8Angeles Mocel Hospital; Universidad Autónoma de México, Ciudad de México, Mexico, 9University of California San Diego, La Jolla, CA

    Background/Purpose: Despite available PsA treatments, a portion of PsA patients (pts) does not achieve improvements in PsA signs and symptoms according to ACR response criteria.…
  • Abstract Number: 2130 • ACR Convergence 2022

    Apremilast in Bio-Naïve Patients with Early Psoriatic Arthritis: A National, Real-Life, Multicenter, Non-Interventional, Prospective, 52-week Cohort Study

    Petros P. Sfikakis1, Dimitrios Vassilopoulos2, Gkikas Katsifis3, Georgios Vosvotekas4, Theodoros Dimitroulas5, Argyro Repa6, Grigorios Sakellariou7, THEODORA SIMOPOULOU8, Athanasios Georgountzos9, Andreas Bounas10, Panagiotis Georgiou11, Evangelia Mole12, Evangelia Kataxaki13, Stamatis Nick Liossis14, Evangelos Theodorou15, Christina Antoniadou16, EVANGELOS THEOTIKOS17, PANAYIOTIS VLACHOYIANNOPOULOS18, THEODORA MARKATSELI19, Angeliki Kekki20, NIKOLAOS ANTONAKOPOULOS21 and Dimitrios Boumpas22, 1Joint Academic Rheumatology Program, National and Kapodistrian University of Athens, School of Medicine, Athens, Greece, 2Clinical Immunology-Rheumatology Unit, 2nd Department of Internal Medicine and Laboratory, National and Kapodistrian University of Athens, School of Medicine, Hippokration General Hospital, Athens, Greece, 3Naval Hospital of Athens, Athens, Greece, 4Euromedica General Clinic of Thessaloniki, Thessaloniki, Greece, Thessaloniki, Greece, 54th Department of Internal medicine, Hippokration Hospital, School of medicine, Aristotle University of Thessaloniki, Thessaloniki, Greece, Thessaloniki, Greece, 6Rheumatology, Clinical Immunology and Allergy, University of Crete School of Medicine, Heraklion, Crete, Greece, 7Department of Rheumatology, 424 General Army Hospital, Thessaloniki, Greece, Thessaloniki, Greece, 8Clinic of Rheumatology and Clinical Immunology, University Hospital of Larissa, Larissa, Greece, Larissa, Larisa, Greece, 9General Hospital of Athens G. Gennimatas, Athens, Greece, 10Olympion private General Clinic of Patras, Patras, Greece;, Patra, Akhaia, Greece, 11Rheumatology Unit, Agios Andreas Hospital, Patras, Greece, PATRA, Akhaia, Greece, 12Department of Rheumatology, KAT General Hospital of Attica, Athens, Greece, 13Rheumatology Unit, Thriasio General Hospital of Elefsina, Magoula, Greece, 14Division of Rheumatology, Department of Internal Medicine, Patras University Hospital, University of Patras Medical School, Patras, Greece, Patras, Akhaia, Greece, 15Rheumatology Clinic 251 Hellenic Air Force Hospital, Athens, Greece, 16First Department of Internal Medicine, University Hospital of Alexandroupolis, Democritus University of Thrace, Alexandroupolis, Greece, 17Rheumatology Department, Asklepieion Voulas General Hospital, Athens, Greece, 18Department of Pathophysiology, Medical School, National and Kapodistrian University of Athens, Athens, Greece, 19Rheumatology Clinic, Department of Internal Medicine, Medical School, University of Ioannina, Ioannina, Greece, 20Genesis Pharma SA, Halandri, Greece, 21Genesis Pharma SA, Chalandri, Greece, 224th Department of Internal Medicine, "Attikon" University Hospital, Athens, Joint Academic Rheumatology Program, Medical School, National and Kapodistrian University of Athens, Athens, Greece

    Background/Purpose: Apremilast is a targeted synthetic disease-modifying anti-rheumatic drug (tsDMARD) approved for psoriatic arthritis (PsA). Few clinical studies assessing treatment regimens in PsA have focused…
  • Abstract Number: 2146 • ACR Convergence 2022

    Efficacy of Upadacitinib in Patients with Psoriatic Arthritis and Prior Exposure to Anti-TNF Therapy in the SELECT-PsA 2 Trial Through 2 Years

    Philip J Mease1, Rodrigo Luppino Assad2, Shigeyoshi Tsuji3, Pascal Richette4, Arathi Setty5, Erin McDearmon-Blondell6, Tianming Gao5, Sandra Ciecinski6 and Filip Van den bosch7, 1Swedish Medical Center/Providence St. Joseph Health, Seattle, WA, 2Department of Internal Medicine, Ribeirão Preto Medical School, University of São Paulo, São Paulo, Brazil, 3Department of Orthopaedics and Rheumatology, Nippon Life Hospital, Osaka, Japan, 4Department of Rheumatology, Hôpital Lariboisière, Assistance Publique-Hôpitaux de Paris, Paris, France, 5AbbVie, Inc., North Chicago, IL, 6AbbVie, Inc., Mettawa, IL, 7Department of Internal Medicine and Paediatrics, Ghent University and VIB Centre for Inflammation Research, Ghent, Belgium

    Background/Purpose: Patients with psoriatic arthritis (PsA) who experience anti-TNF failure and switch to another TNF inhibitor as second- or third-line therapy typically show poorer responses…
  • Abstract Number: 0198 • ACR Convergence 2022

    Patient Perspectives on Janus Kinase Inhibitor Use in the Treatment of Inflammatory Arthritis

    Savia de Souza1, Andrew Bassett2, Ruth Williams2 and Elena Nikiphorou3, 1Independent, London, United Kingdom, 2King's College London, London, United Kingdom, 3Leiden University Medical Center & King's College London, London, United Kingdom

    Background/Purpose: Janus kinase inhibitors (JAKi) have relatively recently been licensed to treat inflammatory arthritis (IA); specifically rheumatoid arthritis (RA) and psoriatic arthritis (PsA). They differ…
  • Abstract Number: 0402 • ACR Convergence 2022

    Opioid Use and Healthcare Utilization in Adults with PsA and AS

    Alexis Ogdie1, Sofia Pedro2, Jean Liew3 and Kaleb Michaud4, 1Department of Medicine, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, 2Forward, The National Databank for Rheumatic Diseases, Wichita, KS, 3Boston University, Boston, MA, 4University of Nebraska Medical Center, Omaha, NE

    Background/Purpose: Opioid use among individuals with spondyloarthritis is common, reported to be ~20-30% in some cohorts. Data on whether this subset of patients have higher…
  • Abstract Number: 1012 • ACR Convergence 2022

    Comparison of Sacroiliac CT Findings in Patients with and Without Psoriatic Arthritis: Results of the CASIPSA Study

    Olivier Fakih1, Andre Ramon2, Clément Prati1, Paul Ornetti3, Daniel Wendling4 and Frank Verhoeven1, 1Service de rhumatologie, CHU de Besançon, Besançon, France, 2University Hospital of DIJON, Rheumatology, Dijon, France, 3Service de rhumatologie, CHU de Dijon, Dijon, France, 4CHU, University Teaching Hospital, Besançon, France

    Background/Purpose: Psoriatic arthritis (PsA) is an inflammatory arthritis associated with various rheumatological manifestations, such as arthritis or enthesitis, predominantly in the peripheral skeleton. However, the…
  • Abstract Number: 1039 • ACR Convergence 2022

    Differential Retention of Adalimumab and Etanercept Biosimilars Compared to Originator Treatments: Results of a Retrospective French Multicentre Study

    Guillaume LARID1, Guy Baudens2, Alexis DANDURAND1, Pascal COQUERELLE3, Vincent Goeb4, Marie-Hélène Guyot5, Laurent Marguerie6, Frédéric MAURY7, Viellard Eric8, Eric Houvenagel9, Jean Hugues SALMON10, René-Marc Flipo11 and elisabeth gervais1, 1CHU Poitiers, Poitiers, France, 2Private practice, Valenciennes, France, 3CH Béthune, Béthune, France, 4CHU Amiens, Amiens, France, 5Private practice, Roubaix, France, 6Institut Calot, Berck-Sur-Mer, France, 7Private practice, Béthune, France, 8Private practice, St. Malo, France, 9Groupement Hospitalier de l'Institut Catholique de Lille, Lomme, France, 10Reims University Hospital, Reims, France, 11CHU Lille, Boulogne-Billancourt, France

    Background/Purpose: Studies have demonstrated equivalence in term of efficacy and safety of biosimilars (bsDMARDs) compared to the originals treatments (boDMARDs) and in switching situation. Less…
  • Abstract Number: 1235 • ACR Convergence 2022

    Fibroblast Activation in Psoriasis Patients Assessed by 68Ga-FAPI-04 PET-CT Is Associated with Progression to Psoriatic Arthritis

    Filippo Fagni1, David Simon2, Arnd Kleyer2, Koray Tascilar2, Jule Taubmann3, Sara Bayat1, Ioanna Minopoulou3, Melek Yalcin Mutlu3, Armin Atzinger4, Torsten Kuwert4, Georg Schett5 and Chrstian Schmidkonz4, 1University Hospital Erlangen; Department of Internal Medicine 3 - Rheumatology and Immunology, Erlangen, Germany, 2Department of Internal Medicine 3 – Rheumatology and Immunology, Friedrich-Alexander-University Erlangen-Nürnberg and Universitätsklinikum Erlangen, 91054 Erlangen, Germany; Deutsches Zentrum Immuntherapie, Friedrich-Alexander-UniversityErlangen-Nürnberg and Universitätsklinikum Erlangen, Erlangen, Germany, 3University Hospital Erlangen, Department of Internal Medicine 3 - Rheumatology and Immunology, Erlangen, Germany, 4Friedrich-Alexander University (FAU) Erlangen-Nuremberg, Erlangen, Germany, 5Universitätsklinikum Erlangen, Erlangen, Germany

    Background/Purpose: Prevalence of subclinical inflammatory lesions is high in patients with cutaneous psoriasis and constitutes a -risk constellation for the development of psoriatic arthritis (PsA)1.…
  • Abstract Number: 1498 • ACR Convergence 2022

    The Association Between Sonographic Enthesitis with Sonographic Synovitis and Tenosynovitis in Psoriatic Arthritis

    gavriel Balulu1, Victoria Furer1, Jonathan Wollman2, David Levartovsky1, Valerie Aloush1, Ofir Elalouf1, Hagit Sarbagil-Maman3, Liran Mendel2, Sara Borok1, Daphna Paran1, Ori Elkayam3 and Ari Polachek1, 1Tel Aviv Medical Center, Tel Aviv, Israel, 2Department of Rheumatology, Tel Aviv Sourasky Medical Center, Tel Aviv University, Tel Aviv, Israel, 3Tel Aviv Sourasky Medical Center, Tel Aviv, Israel

    Background/Purpose: Enthesitis is considered a hallmark of psoriatic arthritis (PsA). Ultrasound (US) is considered a more accurate tool for the assessment of enthesitis compared to…
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