ACR Meeting Abstracts

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Abstracts tagged "Psoriatic arthritis"

  • Abstract Number: 1815 • ACR Convergence 2023

    The Association of Body Mass Index with SARS-CoV-2 Infection (COVID-19) in Patients with Inflammatory Arthritis on Biologic Disease Modifying Anti-Rheumatic Drugs: Results from the Singapore National Biologics Register

    Preeti Dhanasekaran1, Margaret Ma2, Manjari Lahiri2, Li Wearn Koh3, Stanley Angkodjojo4, Andrew Yu Keat Khor5, James Jiaqi Liu6, Stephanie Wong7 and Siaw Ing Yeo6, 1National University of Singapore, Singapore, Singapore, 2National University Hospital, Singapore, Singapore, 3Tan Tock Seng Hospital, Braddell Heights, Singapore, 4Sengkang General Hospital / Singhealth, Singapore, Singapore, 5Changi General Hospital, Singapore, Singapore, 6Singapore General Hospital, Singapore, Singapore, 7Tan Tock Seng Hospital, Singapore, Singapore

    Background/Purpose: To determine the association of body mass index (BMI) with incident COVID-19 infection in patients with inflammatory arthritis (IA) using biologic disease-modifying anti-rheumatic drugs…
  • Abstract Number: 2236 • ACR Convergence 2023

    Guselkumab Provides Rapid Clinically Meaningful Improvements in Clinical and Patient Reported Outcomes and Sustained Disease Control of Psoriatic Arthritis

    Jeffrey R Curtis1, Atul Deodhar2, Enrique Soriano3, Emmanouil Rampakakis4, May Shawi5, Natalie shiff6, Marcie Strauss7, Chenglong Han8, William R Tillett9 and Dafna Gladman10, 1Division of Clinical Immunology and Rheumatology, University of Alabama, Birmingham, AL, 2Division of Arthritis and Rheumatic Disease, Oregon Health & Science University, Portland, OR, 3Rheumatology Section, Internal Medicine Services, Hospital Italiano de Buenos Aires, and University Institute Hospital Italiano de Buenos Aires, Buenos Aires, Argentina, 4McGill University, Department of Pediatrics / JSS Medical Research, Scientific Affairs, Montreal, QC, Canada, 5Immunology, Janssen Research & Development, LLC, Titusville, NJ, 6Immunology, Janssen Scientific Affairs, LLC / Adjunct, Community Health and Epidemiology, University of Saskatchewan, Horsham, PA, 7MEDASOURCE, Medical Group, Indianapolis, IN, 8Immunology, Janssen Global Services, LLC, Malvern, PA, 9Department of Rheumatology, Royal National Hospital for Rheumatic Diseases, Bath, United Kingdom, 10Schroeder Arthritis Institute, Krembil Research Institute, Toronto Western Hospital, Department of Medicine, University of Toronto, Toronto, ON, Canada

    Background/Purpose: Guselkumab (GUS) has demonstrated robust efficacy across key PsA domains at Week (W) 24, with effects sustained or further enhanced through 2 years. Timing…
  • Abstract Number: 2252 • ACR Convergence 2023

    Bimekizumab Maintained Efficacy Responses Through 52 Weeks in Patients with Psoriatic Arthritis and Inadequate Response or Intolerance to TNF-α Inhibitors Who Were Responders at Week 16: Results from a Phase 3, Randomized Study

    William R Tillett1, Joseph Merola2, Yoshiya Tanaka3, Ennio G Favalli4, Dennis McGonagle5, Diamant Thaçi6, Jessica A Walsh7, Barbara Ink8, Rajan Bajracharya8, Jason Coarse9 and Christopher T Ritchlin10, 1Department of Rheumatology, Royal National Hospital for Rheumatic Diseases, Bath, United Kingdom, 2Harvard Medical School, Brigham and Women's Hospital, Newton, MA, 3University of Occupational and Environmental Health, Kitakyushu, Japan, 4ASST Gaetano Pini-CTO, University of Milan, Department of Rheumatology, Milan, Italy, 5Leeds Biomedical Research Centre, University of Leeds, Leeds, United Kingdom, 6Institute and Comprehensive Center for Inflammation Medicine, University of Lübeck, Lübeck, Germany, 7Salt Lake City Veterans Affairs Health and University of Utah Health, Division of Rheumatology, Salt Lake City, UT, 8UCB Pharma, Slough, United Kingdom, 9UCB Pharma, Morrisville, NC, 10University of Rochester Medical School, Rochester, NY

    Background/Purpose: PsA is a chronic disease affecting multiple domains; however, patients (pts) can experience loss of response with long-term therapy.1 Therefore, maintaining long-term treatment responses…
  • Abstract Number: 0327 • ACR Convergence 2023

    Self-management Strategies and Self-efficacy in Patients Living with Inflammatory Arthritis: Findings from a Quality Improvement Project in a Tertiary Centre

    Saadia Sasha Ali1, Karafotias Ioasaf2, Bechman Katie3, Andrew Rutherford4, Sophia Steer3 and Elena Nikiphorou3, 1King's College Hospital, Epsom, United Kingdom, 2King's College Hospital, London, United Kingdom, 3King's College London, London, United Kingdom, 4King's College Hospital, London, United Kingdom

    Background/Purpose: The 2021 EULAR guidelines on self-management have made recommendations (rec) to aid with the implementation of self-management strategies in inflammatory arthritis (IA) (1). Their…
  • Abstract Number: 0492 • ACR Convergence 2023

    Axial Spondyloarthritis in Patients with Late-Onset Chronic Low Back Pain (Older Than 45 Years). Axial Spa or Psoriatic Disease with Axial Involvement?

    rodrigo garcía salinas1, Gisel Reyes2, Rosario Jaldín Céspedes2, Felica Almada2 and Sebastián Juan Magri3, 1Arthritis and Spondyloarthritis Unit, Hospital Italiano de La Plata, National University of La Plata, La Plata, Argentina, 2Hospital Italiano de La Plata, La Plata, Argentina, 3Hospital Italiano La Plata, Melchor Romero, Argentina

    Background/Purpose: It is known that patients diagnosed with axSpA do not subsequently meet the classification criteria. The Objectives are: To estimate the diagnostic prevalence of…
  • Abstract Number: 0508 • ACR Convergence 2023

    Assessment of Pain Outcomes in a Phase 2 Trial of a Selective, Allosteric Tyrosine Kinase 2 Inhibitor, Deucravacitinib, in Patients with Active PsA

    Philip J. Mease1, Lihi Eder2, Alexis R Ogdie3, Atul Deodhar4, Subhashis Banerjee5, Miroslawa Nowak5, Jiyoon Choi6, Thomas Lehman7 and Vibeke Strand8, 1Swedish Medical Center/Providence St. Joseph Health and University of Washington School of Medicine, Seattle, WA, 2Women’s College Research Institute, Division of Rheumatology, University of Toronto, Toronto, ON, Canada, 3University of Pennsylvania, Philadelphia, PA, 4Division of Arthritis and Rheumatic Disease, Oregon Health & Science University, Portland, OR, 5Bristol Myers Squibb, Princeton, NJ, 6Bristol Myers Squibb, Lawrenceville, NJ, 7Bristol Myers Squibb, Philadelphia, PA, 8Stanford University, Palo Alto, CA

    Background/Purpose: Pain is commonly cited by patients with PsA as affecting their daily activities and quality of life and may differ by sex1. In addition…
  • Abstract Number: 0981 • ACR Convergence 2023

    Time Trends in Overall Infection Risk in Patients with Inflammatory Arthritides Treated with Tumor Necrosis Factor Inhibitors

    Aron Hjalti Bjornsson1, Telma Thrastardottir2, Bjorn Gudbjornsson3 and Thorvardur Love4, 1Landspitali University Hospital and the University of Iceland, Reykjavík, Iceland, 2University of Iceland, Reykjavik, Iceland, 3Centre for Rheumatology Research, University Hospital, Reykjavik, Iceland, 4Landspitali University Hospital and the University of Iceland, Reykjavik, Iceland

    Background/Purpose: Infections are a known complication of disease-modifying therapy in rheumatic patients but have also been associated with the diseases being treated. Biosimilars have increased…
  • Abstract Number: 1414 • ACR Convergence 2023

    Effects of Apremilast on Changes in Cardiometabolic Parameters by Diabetes and Obesity Status in Patients with Psoriatic Arthritis

    Philip J. Mease1, Dafna Gladman2, Iain McInnes3, Sue Cheng4, Stephen Colgan5, Yuri Klyachkin6, Lichen Teng7 and Nehal Mehta8, 1Swedish Medical Center/Providence St. Joseph Health and University of Washington School of Medicine, Seattle, WA, 2Schroeder Arthritis Institute, Krembil Research Institute, Toronto Western Hospital, Department of Medicine, University of Toronto, Toronto, ON, Canada, 3University of Glasgow, Glasgow, United Kingdom, 4Amgen, Inc., Bradenton, FL, 5Amgen, Inc., Halton Hills, ON, Canada, 6Amgen, Inc., Lexington, KY, 7Amgen, Inc., Thousand Oaks, CA, 8George Washington University School of Medicine, Washington, DC

    Background/Purpose: The prevalence of cardiometabolic diseases including obesity and diabetes is higher in patients with psoriatic arthritis (PsA) than those without PsA. Apremilast (APR) is…
  • Abstract Number: 1431 • ACR Convergence 2023

    Izokibep, a Unique IL-17A Inhibitor, Improves Patient-Reported Outcomes in Patients with Active Psoriatic Arthritis up to Week 46 – Phase 2 RCT Results

    Peter C. Taylor1, Kurt de Vlam2, Philip J. Mease3, Paul M. Peloso4, Dieter Wetzel5, Apinya Lertratanakul6, Nikolai Brun7, Brian Wiens8, Jan Brandt-Juergens9, Edit Drescher10, Eva Dokoupilova11, Anna Rowińska-Osuch12, Nadia Abdel-Kader Martin13 and Frank Behrens14, 1Nuffield Department of Orthopedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, Oxford, United Kingdom, 2University Hospitals Leuven, Leuven, Belgium, 3Swedish Medical Center/Providence St. Joseph Health and University of Washington School of Medicine, Seattle, WA, 4ACELYRIN, INC., Naples, FL, 5toclinco GmbH, Freiburg im Breisgau, Germany, 6ACELYRIN, Chicago, IL, 7Affibody AB, Solna, Sweden, 8ACELYRIN, Inc., Half Moon Bay, CA, 9rheumatologische Schwerpunktpraxis, Berlin, Germany, 10Csolnoky Ferenc Hospital / Vital Medical Center Private Clinci, Veszprém, Hungary, 11Masaryk University, Faculty of Pharmacy, Department of Pharmaceutical Technology; MEDICAL PLUS sro, Brno, Czech Republic, 12ETG Warszawa, Warsaw, Poland, 13Hospital Quironsalud Infanta Luisa, Sevilla, Spain, 14Goethe University, Division of Rheumatology, University Hospital and Fraunhofer Institute for Translational Medicine & Pharmacology, Frankfurt, Germany

    Background/Purpose: Izokibep is a novel small protein IL-17A inhibitor, unique for its high IL-17A binding affinity, a small size at 18.6 kD and albumin binding…
  • Abstract Number: 1651 • ACR Convergence 2023

    Beneficial Effect of Temporary Methotrexate Interruption on B and T Cell Responses upon SARSCoV-2 Vaccination in Patients with Rheumatoid Arthritis or Psoriatic Arthritis

    Esther Vicente Rabaneda1, Pedro Martínez-Fleta2, Ana Triguero-Martínez2, Emilia Roy3, Miren Uriarte-Ecenarro4, Francisco Gutiérrez-Rodríguez4, Patricia Quiroga4, Ana Romero4, Nuria Montes2, Laura Esparcia Pinedo2, María Aranzazu Alfranca2, Rosario Garcia-Vicuna5, Francisco Sánchez-Madrid2, Isidoro González-Álvaro4 and Santos Castañeda5, 1Rheumatology, Hospital Universitario de La Princesa, Madrid, Spain, 2Division of Immunology, Hospital Universitario de La Princesa, Madrid, Spain, 3Division of Internal Medicine, Hospital Universitario de La Princesa, Madrid, Spain, 4Division of Rheumatology, Hospital Universitario de La Princesa, IIS-Princesa, Madrid, Spain, 5Hospital Universitario de la Princesa, Madrid, Spain

    Background/Purpose: Previous published works have raised the concern that methotrexate (MTX) might have a negative effect on immune response upon vaccine administration. At the beginning…
  • Abstract Number: 1860 • ACR Convergence 2023

    Evaluation of the Receipt of Adequate Pharmacological and Psychological Treatment for Incident Depression and Anxiety in Individuals Living with Inflammatory Arthritis

    Alyssa Howren1, Eric Sayre2, J. Antonio Avina-Zubieta3, Joseph Puyat1, Deborah Da Costa4, Hui Xie5, Amit Gupta1 and Mary De Vera1, 1University of British Columbia, Vancouver, BC, Canada, 2British Columbia Centre on Substance Use, Vancouver, BC, Canada, 3Arthritis Research Canada, Vancouver, BC, Canada, 4McGill University, Pointe-Claire, QC, Canada, 5Simon Fraser University, Richmond, BC, Canada

    Background/Purpose: To describe patterns of pharmacological and psychological treatment and evaluate the receipt of minimally adequate treatment for incident depression and anxiety in individuals with…
  • Abstract Number: 2237 • ACR Convergence 2023

    Upadacitinib in Refractory Psoriatic Arthritis. Multicenter Study of 134 Patients in Clinical Practice

    Eva Galindez-Agirregoikoa1, Diana Prieto-Peña2, Maria Luz Garcia Vivar1, Lucia Vega-Alvarez1, Cristina Vergara3, Irati Urionaguena4, Consuelo Ramos-Giráldez5, Raquel Almodovar6, Beatriz Joven Ibáñez7, Rosario Garcia-Vicuna8, Vega Jovani9, Teresa González10, Àngels Martínez-Ferrer11, Ana Urruticoechea Arana12, Bryan Josue Flores Robles13, Cristina Campos Fernández14, Lilian Maria Lopez Nunez15, Joaquin Maria Belzunegui Otano16, Marina Pavia Pascual17, Esteban Rubio18, Angel Ramos-Calvo19, Noemi Busquets20, Ana Pérez Gómez21, Francisco Miguel Ortiz Sanjuan22, Rafael Benito Melero-Gonzalez23, Cristina Macía24, María Ángeles Puche Larrubia25, Jose Antonio Pinto Tasende26, Cristina Fernandez27, Maria Paz Martinez-Vidal28, Jaime Calvo- Alén29, Emma Beltran-Catalan30, Mireia Moreno31, Silvia Pérez-Barrio32, iñigo Gorostiza Hormaeche1 and Ricardo Blanco33, 1Basurto University Hospital, Bilbao, Spain, 2Hospital Universitario Marqués de Valdecilla, Santander, Spain, 3Hospital Universitario Infanta Sofía, Madrid, Spain, 4GALDAKAO-USANSOLO UNIVERSITY HOSPITAL, GERNIKA-LUMO, Spain, 5Rheumatology Department Hospital Universitario Virgen de Valme, Sevilla, Spain, 6Alcorcón Foundation University Hospital, Madrid, Spain, 7Hospital Universitario 12 de Octubre, Madrid, Spain, 8Hospital Universitario de la Princesa, Madrid, Spain, 9Department of Rheumatology, Hospital General Universitario Dr. Balmis, Alicante, Spain, 10Hospital General Universitario Gregorio Marañón, Madrid, Spain, 11Hospital Universitario Dr Peset Valéncia, Valéncia, Spain, 12Hospital Can Misses, Ibiza, Spain, 13Hospital Universitario San Pedro, Logroño, Spain, 14Hospital General Universitario Valencia, Valencia, Spain, 15Son llatzer, Palmanyola, Spain, 16University Hospital Donostia, Donostia-San Sebasti, Spain, 17Hospital Universitario Puerta de Hierro Majadahonda, Madrid, Spain, 18Servicio Andaluz Salud, Sevilla, Spain, 19Complejo Hospitalario de Soria, Soria, Spain, 20HOSP. GENERAL DE GRANOLLERS, GRANOLLERS, Spain, 21Rheumatology, Hospital Principe de Asturias, Alcalá de Henares, Spain, 22Hospital Universitario y Politecnico La Fe, Valencia, Spain, 23CHU Vigo, O Carballino, Spain, 24Hospital Universitario Ramón y Cajal, Madrid, Spain, 25Department of Rheumatology, Reina Sofia University Hospital, Cordoba, Spain, 26Rheumatology department, Complexo Hospitalario Universitario A Coruña (CHUAC). Instituto de Investigación Biomédica A Coruña (INIBIC), A Coruña, Spain, 27Hospital Universitario San Juan de Alicante, Alicante, Spain, 28Hospital Universitario San Juan Alicante, Alicante, Spain, 29Rheumatology, Bioaraba Research Unit, Hospital Universitario Araba, Vitoria, Spain, 30HOSPITAL DEL MAR, Barcelona, Spain, 31Parc Tauli Hospital Universitari, I3PT(UAB), Barcelona, Spain, 32Hospital Universitario de Basurto, Bilbao, Spain, 33Hospital Universitario Marqués de Valdecilla, IDIVAL, Santander, Spain

    Background/Purpose: The EMA authorized Upadacitinib (UPA) in PsA in January 2021. UPA has shown efficacy in PsA refractory to anti-TNF in a clinical trial (RCT).…
  • Abstract Number: 2253 • ACR Convergence 2023

    Deucravacitinib, an Oral, Allosteric, Selective Tyrosine Kinase 2 Inhibitor, in Patients with Plaque Psoriasis Who Screened Positive for Psoriatic Arthritis in POETYK PSO-1 and POETYK PSO-2: Effect on Joint Pain and Peripheral Joint Disease vs Placebo and Apremilast

    Joseph Merola1, Philip J. Mease2, April W. Armstrong3, Vibeke Strand4, Thomas Lehman5, Jiyoon Choi6, Brandon Becker6, Yichen Zhong7, Matthew J. Colombo7, Diamant Thaçi8, Androniki Bili7 and Alice B. Gottlieb9, 1Harvard Medical School, Brigham and Women's Hospital, Newton, MA, 2Swedish Medical Center/Providence St. Joseph Health and University of Washington School of Medicine, Seattle, WA, 3Keck School of Medicine of University of Southern California, Los Angeles, CA, 4Stanford University, Portola Valley, CA, 5Bristol Myers Squibb, Philadelphia, PA, 6Bristol Myers Squibb, Lawrenceville, NJ, 7Bristol Myers Squibb, Princeton, NJ, 8Institute and Comprehensive Center for Inflammation Medicine, University of Lübeck, Lübeck, Germany, 9Icahn School of Medicine at Mount Sinai, New York, NY

    Background/Purpose: As 41% of patients with psoriasis may be undiagnosed for psoriatic arthritis, treatments must relieve both dermatologic and musculoskeletal symptoms. Deucravacitinib (DEUC), an oral,…
  • Abstract Number: 0338 • ACR Convergence 2023

    Comparative Disease Burden in Patients with Rheumatoid Arthritis, Psoriatic Arthritis or Ankylosing Spondylitis: Data from COVAD Patient-reported E-survey

    Diego Benavent1, Marco Fornaro2, Florenzo Iannone3, Lorenzo Cavagna4, Masataka Kuwana5, Naveen R6, Vishwesh Agarwal7, Jessica Day8, Mrudula Joshi9, Sreoshy Saha10, Kshitij Jagtap11, Wanruchada Katchamart12, Phonpen Akarawatcharangura Goo13, Binit Vaidya14, Tsvetelina Velikova15, Parikshit Sen16, Samuel Shinjo17, Ai Lyn Tan18, Nelly Ziade19, Marcin Milchert20, Abraham Edgar Gracia-Ramos21, Carlo Caballero22, Hector Chinoy23, Vikas Agarwal6, Rohit Aggarwal24, Latika Gupta25 and Vincenzo Venerito26, 1Hospital la Paz, Madrid, Spain, 2University of Bari, Grottaglie, Italy, 3Rheumatology Unit, Department of Precision and Regenerative Medicine and Ionian Area, University of Bari "Aldo Moro", Bari, Italy, 4Fondazione IRCCS Policlinico San Matteo, Pavia, Italy, 5Nippon Medical School Graduate School of Medicine, Tokyo, Japan, 6Sanjay Gandhi Postgraduate Institute of Medical Sciences (SGPGIMS), Lucknow, India, 7Mahatma Gandhi Missions Medical College, Lucknow, India, 8Walter and Eliza Hall Institute, Melbourne, Australia, 9Byramjee Jeejeebhoy Government Medical College and Sassoon General Hospitals, Pune, India, 10Mymensingh Medical College, Faridpur, Bangladesh, 11Seth Gordhandhas Sunderdas Medical College and King Edwards Memorial Hospital, Mumbai, India, 12Mahidol University, Bangkok, Thailand, 13Department of Medicine, Queen Savang Vadhana Memorial Hospital, Chonburi, Thailand, 14National Center for Rheumatic Diseases (NCRD), Ratopul, Kathmandu, Nepal., Kathmandu, India, 15Department of Clinical Immunology, Medical Faculty, University Hospital "Lozenetz", Sofia University St. Kliment Ohridski, Sofia, Bulgaria, 16Maulana Azad Medical College, 2-Bahadurshah Zafar Marg, New Delhi, Delhi-110002, India., Dalhi, India, 17Faculdade de Medicina FMUSP, Universidade de Sao Paulo, São Paulo, Brazil, 18University of Leeds, Leeds, United Kingdom, 19Saint-Joseph University, Beirut, Lebanon, 20Department of Internal Medicine, Rheumatology, Diabetology, Geriatrics and Clinical Immunology, Pomeranian Medical University in Szczecin, Szczecin, Poland, 21Department of Internal Medicine, General Hospital, National Medical Center "La Raza", Instituto Mexicano del Seguro Social, Av. Jacaranda S/N, Col. La Raza, Del. Azcapotzalco, C.P. 02990, Mexico City, Mexico, 22Universidad del Norte, Barranquilla, Colombia, 23The University of Manchester, Sale, United Kingdom, 24University of Pittsburgh, Pittsburgh, PA, 25Royal Wolverhampton Trust, Wolverhampton/University of Manchester, United Kingdom, 26Rheumatology Department, Università degli Studi di Bari, Bari, Italy

    Background/Purpose: Rheumatoid arthritis (RA) and spondyloarthritis (SpA), including either Psoriatic Arthritis (PsA) and Ankylosing Spondylitis (AS), are some of the most commonly diagnosed autoimmune rheumatic…
  • Abstract Number: 0493 • ACR Convergence 2023

    Axial Disease Activity in Psoriatic Arthritis Is Higher in Patients with Carotid Plaque

    Rosa Arvizu-Rivera1, Valeria Gonzalez-Gonzalez2, Dionicio A. Galarza-Delgado3, Iris Colunga3, José Ramón Azpiri-López3, Victor Beltran4, Angel Arias Peralta5 and Jesus Alberto Cardenas-De la Garza6, 1Hospital Universitario "Dr. José Eleuterio Gonzalez", Escobedo, Mexico, 2Universidad Autónoma de Nuevo León, Monterrey, Mexico, 3Hospital Universitario UANL, Monterrey, Mexico, 4Rheumatology Service Hospital Universitario "Dr. José Eleuterio González", Monterrey, Mexico, 5Medicine Faculty, Universidad Autonoma De Nuevo Leon, Monterrey, Mexico, 6Hospital Universitario "Dr. José Eleuterio González", San Nicolas, Mexico

    Background/Purpose: Approximately half of the patients with psoriatic arthritis (PsA) present with axial disease. Previously, it was reported that PsA-patients with axial involvement present a…
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