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Abstracts tagged "psoriatic arthritis and synovitis"

  • Abstract Number: 642 • 2017 ACR/ARHP Annual Meeting

    Downstream Effects of Apremilast in Human Arthritic Ex Vivo Models

    Tue Wenzel Kragstrup1,2, Søren Lomholt2, Morten Aagaard Nielsen2, Line Dam Heftdal2, Peter H. Schafer3 and Bent Deleuran2,4, 1Randers Regional Hospital, Randers, Denmark, 2Department of Biomedicine, Aarhus University, Aarhus, Denmark, 3Department of Translational Development, Celgene Corporation, Summit, NJ, 4Department of Rheumatology, Aarhus University Hospital, Aarhus, Denmark

    Background/Purpose: Apremilast (Otezla) is a PDE4 inhibitor approved for the treatment of psoriasis and psoriatic arthritis, but the mechanisms of action of apremilast are not…
  • Abstract Number: 1578 • 2014 ACR/ARHP Annual Meeting

    Abatacept Improves Synovitis As Assessed By Magnetic Resonance Imaging (MRI) in Psoriatic Arthritis – Preliminary Analysis from a Single Centre, Placebo-Controlled, Crossover Study

    Agnes Szentpetery1, Eric J. Heffernan2, Muhammad Haroon3, Phil Gallagher1, Anne-Marie Baker1, Martina Cooney1 and Oliver FitzGerald1, 1Rheumatology, St. Vincent's University Hospital, Dublin, Ireland, 2Radiology, St. Vincent's University Hospital, Dublin, Ireland, 3Newmarket On Fergus, Cork University Hospital, Cork, Ireland

    Background/Purpose Abatacept is a soluble, fully human fusion protein which selectively inhibits T-cell activation via the CD80/CD86:CD28 co-stimulation pathway and decreases serum levels of inflammatory…
  • Abstract Number: 1183 • 2014 ACR/ARHP Annual Meeting

    Validation of the Omeract Psoriatic Arthritis Magnetic Resonance Imaging Score for the Hand and Foot in a Randomized Placebo-Controlled Trial

    Daniel Malm1, P. Bird2, Frédérique Gandjbakhch3, Philip J. Mease4, Pernille Bøyesen5, Mikkel Østergaard6, Charles G. Peterfy7 and Philip G. Conaghan8, 1Center for Rheumatology and Spinal Diseases, Copenhagen University Hospital at Glostrup, Glostrup, Denmark, 2Combined Rheumatology Practice, Sydney, Australia, 3Service de Rhumatologie, Groupe Hospitalier Pitie Salpetriere, Paris, France, 4Swedish Medical Center and University of Washington, Seattle, WA, 5Department of Rheumatology, Diakonhjemmet Hospital, Oslo, Norway, 6Center for Rheumatology and Spine Diseases, Glostrup Hospital, Copenhagen Center for Arthritis Research, Center for Rheumatology and Spine Diseases, Glostrup Hospital, Glostrup, Denmark, 7Spire Sciences LLC, Boca Raton, FL, 8Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds and NIHR Leeds Musculoskeletal Biomedical Research Unit, Chapel Allerton Hospital, Leeds, United Kingdom

    Background/Purpose The joint involvement in psoriatic arthritis (PsA) is heterogeneous, and inflammation is seen in both axial and peripheral joints, including the small joints of…
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ACR Pediatric Rheumatology Symposium 2020

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