Abstracts tagged "psoriatic arthritis and signal transduction"

Abstract Number: 1678 • ACR/ARHP Annual Meeting 2016
JAK STAT Kinase Cascade Regulates the IL-23/IL-17 Cytokine Axis in Psoriatic Arthritis
Siba P. Raychaudhuri¹ and Smriti K. Raychaudhuri², ¹Davis, CA, ²Rheumatology/Immunology, VA Sacramento Medical Center, Davis, CA
Background/Purpose: Aberrant activation of IL-23/IL-17 cytokine axis is a dominant pathology in the psoriatic disease. IL-23 regulates expansion/maintenance/functional maturation of Th17 cells. Th17 cells along…